Research Article of American Journal of Clinical Research and Reviews
Effect of Malaria Parasite on Platelet Among Pregnant Women in Owerri, Imo State Nigeria
1L. N. Allison ,2 I. Mgbemena,3A. N.C. Amadi, 4M. N.Ezike, 1 A.A. Ukoma, 1 D.O. Iwu
1Department of Biology, Federal University of Technology, Owerri , Nigeria
2Department of Biotechnology, Federal University of Technology, Owerri Imo state, Nigeria
3Department of Zoology, Michael Okpara Federal University of Agriculture Umudike Umuahia, Abia state
4Department of Animal and Environmental Biology,Imo state University Owerri.
Malaria is a formidable global parasitic infection that presents a major health challenge in Tropical countries especially among pregnant women and children. It has a profound alteration or reduction effects on hematological parameters such as platelets in pregnant women. The study was carried out to determine the effects of Plasmodium falciparum on platelets of pregnant women in Owerri, Imo state Nigeria. A total of one hundred and fifty (150) blood samples of pregnant women were collected at Holy Rosary hospital Emekuku in owerri. The blood samples were screened for malaria infection using thick and thin Giemsa blood films. Results showed that 50 (33.33%) were positive for malaria parasite showing significant signs, with visible fever accompanying the infections. Normal platelet number ranges from 150 X 109/L; 400 X 109/L. The association of hematological parameters and diagnosis of malaria infection among people living in malaria endemic areas were retrieved. The most commonly changed parameters are platelet count. Presence of thrombocytopenia in pregnant women from endemic areas was useful as supportive diagnostic criteria for malaria in cases with low levels of parasite number. Therefore, when used with other clinical and microscopy parameters, it can significantly improve malaria diagnosis and timely treatment for malaria infection.
Keywords: Malaria Parasite, Platelet, Pregnant Women, Owerri, Imo State, Nigeria
How to cite this article:
Allison et al., Effect of Malaria Parasite on Platelet Among Pregnant Women in Owerri, Imo State Nigeria. American Journal of Clinical Research and Reviews, 2017; 1:6.
1 Afolabi, (2002). Malaria caused by a single protozoan parasite, by bite of Anopheles. Bio Natl. Tech 10:3-7.
2 Dacie, JV., Lewis, SM., (1991)) ‘Practical Haematological. 5th Edition Churchill Livingstone. Edinburg.
3 Ejezie, M., Michael, O., Clifford, I., (1991) ‘Roll Back Malaria (RBM) programs cause morbidity, resistance, mortality and hindrance to economic development’ Bio. Sci. 19.
4 Essien, EM., (1987). The circulating platelet in acute malaria infection. British journal of haemtology; 72:589-590.
5 Famomdu, AA., Elasoji, SO., (2007) Induced platelet aggregation in sickle cell anaemia. Journal of medical laboratory science.; 6:39-41.
6 Federal Ministry of Health doc. 2000.
7 Fernando, Lozanta, L., Indianzy, Q., (2010). ‘Studies comparing cognitive abilities and functions before and after treatment for severe malaria illness. B.Tech. 33-44.
8 Nneji, Magnus, Q., Alexzander, B., Lewis, I., (2009). Pregnant women at the highest risk of malaria. Science 104:8-11.
9 Riley, and Stewart, (2013) Chronic-infection without severe disease can occur in an immune-deficiency syndrome. Transm 14:14-17.
10 Rogerson, I., Vkymazac, V., Wickyson, Q., (2007). ‘Effects on haematological parameters that is platelet in pregnant women’. Medline 10:89-93.
11 Smith, (1996). ‘Low human immunity or changes in hormonal profiles increase malaria transmission in pregnant women’, B. Tech. 8:4-5.
12 Taylor, Kajfasz, Krafts, K., Hempelmann, E., Howith, (2012). ‘Bed-nets insecticides, Artemisinin-based combination therapies; Science 323: 141-144.
13 Taylor, Kajfsz, Krafts, K., Hempelmann, E., Howith, (2012). ‘Symptoms of malaria as loss of appetite, joint pain, Nausea. Jcoil. Pathology. 13-17.
14 WHO, (2012). Epidemiology and prevalence of malaria parasite study.
15 WHO, (2014). Estimated number of African death children A 437,000-789,000 as a malaria case.
16 WHO, (2012). ‘Evidence Review Group: Intermittent preventive treatment of malaria in pregnancy.
17 WHO, (2008). ‘Malaria as the biggest health burden in sub-Saharan Africa’.
18 WHO, (2006). Origin of malaria from the medevial Italian words.
19 WHO, (2014). Eradication, prevention, control measures of malaria parasite.
20 Wito, (2000). ‘Malaria as the biggest health burden in sub-saharan Africa’. Microbiology 14:103-105