AJG (2018), Vol. 1, Issue 01

  • Selection of Reference Genes in Vitis Vinifera Inoculated With Xanthomonas Campestris

    Selection of Reference Genes in Vitis Vinifera Inoculated With Xanthomonas Campestris Silva, J.B.1, Oliveira Silva, R.L.O2, Araújo, A.C.C3, Oliveira, M.F4, Moura, M.T5, Benko-Iseppon, A.M6 1,3,4 Mestranda do Programa de Pós-Graduação em Ciências Biológicas – UFPE; 2Pós-Doutoranda do Departamento de Ciências Biológicas da UFPE, 5Pós-Doutorando do Departamento de Ciências Veterinárias da UFRPE, 6Docente/Pesquisadora do Departamento de Genética da UFPE Introduction: The selection of reference genes (RGs) is considered as one of the most critical steps for RT-qPCR since these genes must…

  • Main Differences Between Diabetes Mellitus Types 1 and 2 in Relation to Genetic Factors

    Main Differences Between Diabetes Mellitus Types 1 and 2 in Relation to Genetic Factors Silva F.F.L.1; Silva K.S.2 1Biólogo – UFPE; Cursando Especialização em Genética e Biologia Molecular Humana – UFPE; 2Enfermeira – UFPE. Especialista em Educação (UFPE) e Enfermagem do Trabalho (JOAQUIM NABUCO). Introduction:Diabetes mellitus type 1 (DM1) and 2 (DM2), are responsible for more than 95% of the world cases. Being autoimmune DM1, characterized by the destruction of the pancreatic beta cells through the lymphocytes of the body,…

  • Validation of the Conventional PCR technique for diagnosis of AML with NPM1 gene mutation

    Validation of the Conventional PCR technique for diagnosis of AML with NPM1 gene mutation Nascimento L.S.F1; Melo A.S2; Araújo A.R.L3 1Student of Biomedicine – UFPE; 2Researcher from Laboratório central/ CB – UFPE; 3Professor/Researcher from Department of Biophysics – UFPE. Introduction: NPM1 gene mutations are the most frequent mutations in adults with acute myeloid leukemia (AML) they are found in 30% of adult de novo AML and in 60% of AML with normal karyotype. Because its clinical relevancy the European Leukemianet…

  • Genetic Analysis of the Clinical Manifestations of Lipofuscinosis (Batten Syndrome)

    Genetic Analysis of the Clinical Manifestations of Lipofuscinosis (Batten Syndrome) Cursino G.T¹, Donato H.M.G², Luis J.M.S³, Ferreira K.M.L.M4, Soares T.A.B5, Souza M.B.R6 1,2,3,4,5Medical Student – UNICAP; 6Teacher/Researcher of Dept. of Biological Sciences and Health – UNICAP Introduction: Neuronal Ceroid Lipofuscinosis (NCL) is a group of neurodegenerative genetic diseases characterized by the accumulation of lipid pigment in neuronal lysosomes and other tissues. Batten syndrome (BS) is the juvenile form of this group, beginning in childhood, with its primary symptomatology manifested between…

  • Genetic Analysis of Clinical Manifestations of Friedreich Ataxia

    Genetic Analysis of Clinical Manifestations of Friedreich Ataxia Cursino G.T¹, Donato H.M.G², Luis J.M.S³, Ferreira K.M.L.M4, Soares T.A.B5, Souza M.B.R6 1,2,3,4,5Medical Student – UNICAP; 6Teacher/Researcher of Dept. of Biological Sciences and Health – UNICAP Introduction:Friedreich’s ataxia (FA), an autosomal neurodegenerative disorder, conditions a destruction of nerve cells during the progression of the disease, affecting cardiac, bone and pancreatic cells. It has as main symptoms walking difficulty, progressing to changes in limb sensitivity, speech problems, atypical ocular movements, heart disease and…