Concentration of Calcium and Phosphate Serum Following Administration of Zinc in Friesian Holstein Bulls

Concentration of Calcium and Phosphate Serum Following Administration of Zinc in Friesian Holstein Bulls

Sus Derthi Widhyari1, Setyo Widodo1, Agus Wijaya1, Anita Esfandiari1, Retno Wulansari1, Arief Purwo Mihardi1, Lina Maylina1, Helni Novitri2 

1 Faculty of Veterinary Medicine, Bogor Agricultural University,Bogor, Indonesia
2 Student at Faculty of Veterinary Medicine, Bogor Agricultural University,Bogor, Indonesia

International Journal of Animal ResearchMinerals play an important role in bulls as they function to form mucles of and maintain the quality of sperm. Zn mineral in the diet will also affect the levels of calcium and phosphorus in the blood. The objective of this study was to determine the effect of Zn supplementation on the levels of calcium and phosphate serum in Friesian Holstein bulls. This study used ten Friesian Holstein bulls, 16-18 months old and divided into two groups, consisting of five bulls each, i.e. with no added Zn (control) and 60 ppm of Zn supplementation, respectively. Zinc was administered daily for four months. Blood samples were taken before treatment and after the four- month treatment for the examination of calcium and phosphate levels. The result showed that 60 ppm Zn supplementation was not significantly different (p>0.05) on the blood calcium and phosphate levels. However, the calcium level tends to increase while that of phosphate tends to decrease.

Keywords: calcium, Friesian Holstein bulls, phosphorus, Zn

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How to cite this article:
Sus Derthi Widhyari, Setyo Widodo, Agus Wijaya, Anita Esfandiari, Retno Wulansari, Arief Purwo Mihardi, Lina Maylina, Helni Novitri. Concentration of Calcium and Phosphate Serum Following Administration of Zinc in Friesian Holstein Bulls. International Journal of Animal Research, 2018; 2:18. DOI: 10.28933/ijar-2017-19-1901


[1] Azizzadeh, M., Mohri, M., Seifi, H. A. 2005. Effect of oral zinc supplementation on hematology, serum biochemistry, performance and health in neonatal dairy calves. Comp Clin Path. 14: 67-71.
[2] Crenshaw, T. D., Rortvedt, L. A., Hassen, Z. 2011. Triennial Growth Symposium: A novel pathway for vitamin D-mediated phosphate homeostasis: Implications for skeleton growth and mineralization. J. Anim Sci. 89: 1957-1964.
[3] Daghash and Mousa. 2002. Zinc sulfate supplementation to buffalo calves diet and its relation to digentibility, rectal temperature, growth and some blood constituents under hot climatic conditions. Buffalo J. 18:83100
[4] Goff, J. P. 2000. Pathophysiology of calcium and phosphorus disorders. Veterinary Clinics of North America Food Animal Practice. 16: 319-337.
[5] Hadley, K. B., Newman, S. M., Hunt, J. R. 2010. Dietary zinc reduces osteoclast resorption activities and increases markers of osteoblast differentiation, matrix maturation and mineralization in the long bone of growing rats. Journal of Nutrition Biochemistry. 21: 297-303.
[6] Katsumata, S., Masuyama, R., Uehara, M., Suzuki, K. 2005. High-phosphorus diet stimulates receptor activator of nuclear factor-êB ligand mRNA expression by increasing parathyroid hormone secretion in rats. British Journal of Nutrition. 94: 666-674.
[7] Knowlton, K. F and Herbein, J. H. 2002. Phosphorus partitioning during early lactation in dairy cows fed diets varying in phosphorus content. J. Dairy Sci. 85: 1227-1236.
[8] National Research Council. 2001. Nutrient Requirement of Dairy Cattle. Washington (US): National Academi Press.
[9] Nurlena. 2005. Tampilan kalsium dan fosfor darah, produksi susu, ion kalium, dan jumlah bakteri susu sapi perah Friesian Holstein akibat pemberian areas sauropus androgynus (L) Merr (KATU) [tesis]. Semarang (ID): Program Pascasarjana Universitas Diponegoro.
[10]. Scaletti RW, Trammell DS, Smith BA, Harmon RJ. 2003. Role of dietary copper in enhancing resistance to escherichia coli mastitis. J. Dairy Sci. 86: 1240-1249.
[11] Suprijati. 2013. Seng organik sebagai imbuhan pakan ruminansia. Wartazoa. 23: 142-157.
[12] Tasse AM dan Auza FA. 2014. Konsentrasi asam lemak tidak teresterifikasi (nonesterified fatty acid, NEFA), albumin, kalsium dan fosfor dalam plasma sebagai indikator status nutrisi sapi perah laktasi. JITRO. 1: 70-78.
[13] Triphan J, Aumuller G, Brandenburger T, Wilhelm B. 2007. Localization and regulation of plasma membran Ca2+-ATPase in bovine spermatozoa. Eur J Cell Biol. 86: 265-273.
[14] Wong WY, Flik G, Groenen PM, Swinkels DW, Thomas CM, Peereboom JH, Merkus HM, Theunissen. 2001. The impact of calcium, magnesium, zinc, and cooper in blood and seminal plasma on semen parameters in men. Reproductive Toxicology. 15: 131-136.
[15] Wu Z, Satter LD, Blohowiak AJ, Stauffacher RH, Wilson JH. 2001. Milk production, estimated phosphorus exretion and bone characteeristics of dairy cow fed different amounts of phosphorus for two or three years. J.Dairy Sci. 84: 1738-1748.
[16] Young CH, Cooper TG. 2008. Potassium channels involved in human sperm volume regulation, quantitative studies et the protein and mRNA level. Molecular Reproduction and Development. 75: 650-668.