Prevalence and Associated Factors of Antiepileptic Drugnonadherence Among Epileptic Patients Attending at Out Patient Departement of Dilla University Referral Hospital, Dilla,gedeo,snnpr, Southern Ethiopia


Prevalence and Associated Factors of Antiepileptic Drugnonadherence Among Epileptic Patients Attending at Out Patient Departement of Dilla University Referral Hospital, Dilla,gedeo,snnpr, Southern Ethiopia


Maregu Shegaw (BSC) 1, Reta kassa (BSC, MPH )2, Yigrem ali (BSC, MSc)3, Negatu Addissu (BSC, MSc)4

1Depratment of Psychiatry, college of health sciences and Medicine , Dilla University,Ethiopia.
2Depratment of public health, college of health and Medical sciences, Dilla University , Ethiopia.
3Department of psychiatry, college of health sciences and Medicine , Dilla University,Ethiopia
4 Department of Pharmacy, college of health sciences and medicine, Dilla University, Ethiopia


International Journal of Bioscience and Medicine

Background: Antiepileptic drugs are effective in the treatment of epilepsy, but poor adherence to medication is major problem to sustained remission and to functional restoration. Poor adherence to treatment is one of many reasons for pharmacological treatment failure and seizure recurrence. Even though there were studies on the magnitude and associated factors of Antiepileptic drugs non-adherence, there is a shortage of published information regarding the prevalence and associated factors of Antiepileptic drugs none-adherence in Ethiopia.

Objective: To assess prevalence and associated factors of antiepileptic drug none-adherence among epileptic patients attending at Dilla University Referral Hospital

Methods: Institutional based cross sectional study design was conducted at Dilla University Referral Hospital from March to May, 2016. A total of 265 individuals was selected by simplerandom sampling method and interviewed by using structured questionnaire. 8 itemMorisky Medication Adherence Scalewas used to assess the prevalence of antiepileptic drug non adherence. Data was coded and exported to SPSS version 20 for analysis.

Results: The prevalence of Antiepileptic’s drug none-adherence in this study was 38.1% and getting medication by payment [AOR2.009, 95%,CI:1.044, 3.868], Patients who did not got health information about(their illness, duration of treatment and drug side effect) [AOR=0.319,95%,CI:0.184,0.534],  poor social support [AOR=3.06, 95%, CI: 1.47-6.37], skip dose [AOR=2.462,95%,CI:1.375,4.407], patients who were on treatment for 2-5 years [AOR=1.48, 95%, CI: 0.722,3.035]  were found to be  significantly associated (p.

Conclusion: The prevalence of antiepileptic drug none-adherence among patients with epilepsy disorder was found 38.1%. Getting medication by payment, did not receive health information about (the illness, duration of treatment, medication side effect), skip dose, on treatment for 2-5 years, and poor social support were found to be the independent predictor of antiepileptic drug none-adherence.


Keywords:  Antiepileptic Drugs, prevalence, epileptic patients, Ethiopia

Free Full-text PDF