Oral Manifestations in Patients With Acquired Immunodeficiency Syndrome

Oral Manifestations in Patients With Acquired Immunodeficiency Syndrome

Santos, P. M. F.¹, Sales, F.G.M.¹, Teles, L.X.S.¹, Silva, N.C.¹, Vieira, A.C.B.¹, Arruda, H.S.A.²

1Estudantes do Curso de Odontologia – UFPE;
2Pesquisador do departamento de Embriologia/Histologia da UFPE

American Journal of Geographical Research and Reviews

Introduction: The Acquired Immunodeficiency Syndrome (AIDS) is an advanced clinical manifestation of human immunodeficiency virus (HIV) infection. It is characterized by host immunosuppression, manifested by a wide variety of clinical signs and symptoms, many of which are observed in the oral cavity. Objectives: The objective of this study was to evaluate oral manifestations among HIV positive patients and to identify factors associated with such manifestations. Methodology: This article was elaborated from a literature review, firstly, carrying out a bibliographical survey about the chosen theme from scientific articles, from 1990 to 2017 and then selecting the articles that fit the pre-established objectives. Results: Candidiasis and Periodontitis were the oral manifestations found more often. On the other hand, Leukoplasia, herpes and Kaposi’s sarcoma were not found as much as the others. In this analysis, there was a greater risk among patients with low schooling, smokers, with a longer time of HIV infection and higher viral load. Conclusion: The studies confirm the high prevalence of opportunistic oral manifestations due to the infection that compromises the immune system, which causes depletion in the immunological function of the oral mucosa, making it susceptible to several diseases.

Keywords: Immunity; Oral Manifestations; Acquired Immunodeficiency Syndrome

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How to cite this article:
Santos, P. M. F., Sales, F.G.M., Teles, L.X.S., Silva, N.C., Vieira, A.C.B., Arruda, H.S.A.Oral Manifestations in Patients With Acquired Immunodeficiency Syndrome. International Journal of Dental Research and Reviews, 2018, 1:2


1. CAVASSANI, V. G. S. Candidíase oral como marcador de prognóstico em pacientes portadores do HIV. Rev. Bras. Otorrinolaringol, São Paulo, v.68, n.5, 2002.
2. BUCZYNSKI, A. K.; CASTRO, G. F.; SOUZA, I. P. R. O impacto da saúde bucal na qualidade de vida de crianças infectadas pelo HIV: revisão de literatura. Associação Brasileira de Pós-graduação em Saúde Coletiva, Rio de Janeiro, v.13, n.6, p.1797-1805, 2008.
3. GASPARIN, A. B. et al. Prevalência e fatores associados às manifestações bucais em pacientes HIV positivos atendidos em cidade sul brasileira. Cad. Saúde Pública, Rio de Janeiro, v.25, n.6, P.1307-1315, 2009.
4. HOFER, F. D. Lesiones orales asociadas con la enfermedad del virus de inmunodeficiencia humana en pacientes adultos, una perspectiva clínica; Rev. chil. Infectol, Santiago, v.33 supl.1, 2016.
5. AXELL, T. et al. Revised classification of HIV – associated oral lesions. Brit den J, v.170, n.8, p. 305-6, 1991.
6. SOUZA, L. B. et al. Manifestações orais em pacientes com AIDS em uma população brasileira. Pesquisa Odontológica Brasileira, v.14, n.1, p.79-85, 2000.
7. GALLARDO-ROSALES, R. et al. Manifestaciones Orales en pacientes VIH/SIDA del Hospital Base de Valdivia en Chile. Rev. Ces Odont, Medellín, v.29, n.2, p.12-19, 2016.
8. MOTTA, W. K. S. et al. Aspectos demográficos e manifestações clínicas bucais de pacientes soropositivos para o HIV/Aids. Revista de Odontologia da Unesp, Sl, v.43, n.1, p.61-67, 2014.
9. BARONE, R. et al. Prevalence of oral lesions among HIV-infected intravenous drug abusers and other risk groups. Oral Surg, v.69, n.2, p.169-73,1990.
10. LIMA, O. C. C.; SILVEIRA, F. R. X. da; BIRMAN, E. G. Manifestações bucais de origem infecciosa em pacientesHIV-positivos ou com AIDS I: doenças fúngicas. Rev. ABO Nac, v.2, n.1, p.28-32,1994.
11. HIDRATA, C. H. et al. Oral manifestations in AIDS. Braz J Otorhinolaryngol. P. 81:120-3, 2015.
12. WILLIAMS, C. A. et al. HIV – associated periodontitis complicated by necrotizing stomatitis. Oral Surg, v.69, n.3, p.351-5, 1990.
13. EPSTEIN, J.; SCULLY, C. HIV infection: clinical features and treatment of thirty-three homossexual men with Kaposi’s sarcoma. Oral Surg, v.71, n.1, p. 38-41,1991.
14. LASKARIS, G. et al. Manifestações orais em pacientes com AIDS em uma população brasileira. Pesq Odont Bras, v. 14, n. 1, p. 79-85, jan./mar. 2000. signs and symptoms in 160 HIV – infected pa-tients. J Oral Pathol Med, v.21, p.120-3, 1992.
15. BASCONES, A.; SERRANO, C.; CAMPO, J. Manifestaciones de la infección por el virus de la inmunodeficiencia humana en la cavidad bucal Oral manifestations of HIV. Medicina Clínica, v.120, p.426-434, 2003.
16.URIZAR, J. M. A.; GOICOURIA, M. A. E.; VALLE, A. E. Síndrome de inmunodeficiencia adquirida: manifestaciones en la cavidad bucal, Med Oral Patol Oral Cir Bucal, Suppl: S148-57, 2004.
15. LOURENÇO, A. G. et al. Oral Candida spp carriage and periodontal diseases in HIV-infected patients in Ribeirão Preto, Brazil. Rev Inst Med Trop, p.59, 2017.
16. PAULIQUE, N. C. et al. Manifestações bucais de pacientes soropositivos para HIV/AIDS. Archives of Health Investigation, v.6, n.6, p.240-244, 2017.
17. CHAGAS, M. V.; SANTOS, L. O.; ONO, L. M. Manifestações Bucais de Pacientes HIV Atendidos na Fundação de Medicina Tropical do Amazonas (FMT-AM). Rev. Fac. Odontol. Porto Alegre, Manaus, v.50, n.3, p.10-13, 2009.
18. LIMA, O. C. C.; SILVEIRA, F. R. X. da; BIRMAN, E. G. Manifestações bucais de origem infecciosa em pacientes HIV-positivos ou com AIDS I: doenças fúngicas. Rev ABO Nac, v.2, n.1, p.28-32, 1994.
19. FEIGAL, D. et al. The prevalence of oral lesions in HIV – infected homossexual and bissexual men: three San Francisco epidemiological cohorts. AIDS, v.5, n.5, p.519-25, 1991.
20. MONIACI, D.; GRECO, D.; FLECCHIA, G.; RAITERI, R. O.; SINICCO, A. Epidemiology, clinical fea-tures and prognostic value of HIV-1 related oral lesions. J Oral Pathol Med, v.19, p.477-81, 1990.