The Relatıon Between Qualıtatıve And Qantıtatıve Parameters Of Freezıng And Walkıng In Idıopathıc Parkınson’s Dısease


The Relatıon Between Qualıtatıve And Qantıtatıve Parameters Of Freezıng And Walkıng In Idıopathıc Parkınson’s Dısease


Assistant Prof Feyzan CANKURTARAN1, Assistant Prof Murat GÜLTEKİN2, Prof Dr Ferhan SOYUER1, Prof Dr Meral MİRZA2, Assistant Prof Gözde ERTÜRK3

1Nuh Naci Yazgan University, Faculty of Health Sciences, Physical Therapy and Rehabilitation Department, Kayseri/TURKEY
2Erciyes University, School of Medicine, Department of Neurology, Kayseri/TURKEY
3 Erciyes University, School of Medicine, Department of Biostatistics, Kayseri/TURKEY


international journal of aging research

Purpose: Our study is planned for determining the relation of some qualitative and quantitative parameters of freezing phenomenon and walking in patients with Idiopathic Parkinson’s Disease (IPD). Methods: 87 patients (37 -%42.5 female, 50-%57.5 male) in ErciyesUniversity Faculty of Medicine Neurology Department involved in this study. Patients were evaluated by demographic data, Mini Mental State Examination (MMSE), Hoehn- Yahr Scale, the Unified Parkinson’s Disease Rating Scale (UPDRS), freezing, 6 meter walking time, step count, rotation and related to step parameters. Results: Hoehn- Yahr Scale for the involved patients between 1-3, 14 out of their was 1(%16.1) and 17 out of their was 3 (%19.5). Freezing phenomenon was determined in 34 (%39.1) of the patients. There were no statistically difference between freezing and non-freezing patients about age, gender, education, profession, marital status and MMSE (p>0.05). Statistically difference were obsorved between freezing and non-freezing groups about UPDRS, rotation time 360 degrees from right, rotation time 360 degrees from left, balance defect at 360 degrees right rotation, 6m walking time, step count, hesitating gait, arrhythmic stepping, opening arms outside while walking (p<0.05). Discussion: Our study showed freezing phenomenon effects some walking parameters for IPD. Effect of freezing phenomenon on postural instability and It’s effection balance should be investigated. Also exercise programmes in IPD with freezing phenomenon should focus on walking education.


Keywords:   Idiopathic Parkinson’s Disease, freezing, walking


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How to cite this article:
Feyzan CANKURTARAN, Murat GÜLTEKİN, Ferhan SOYUER, Meral MİRZA, Gözde ERTÜRK. The Relatıon Between Qualıtatıve And Qantıtatıve Parameters Of Freezıng And Walkıng In Idıopathıc Parkınson’s Dısease. International Journal of Aging Research, 2018, 1:7. DOI:10.28933/ijoar-2018-06-0701


References:

1. Gu Q, Huang P, Xuan M. Greater Loss of White Matter Integrity in Postural Instability and Gait Difficulty Subtype of Parkinson’s Disease. Can J Neurol Sci. 2014; 41: 763-768.
2. Jellinger KA. The pathomechanisms underlying Parkinson’s disease. Expert Rev. Neurother 2014; 14: 199–215.
3. Vaugoyeau M, Viel S, Assaıante C, Aamblard B, Azulay JP. Impaired vertical postural control and proprioceptive integration deficits in parkinson’s disease. Neuroscience. 2007;146: 852–863.
4. Bloem BR, Hausdorff JM, Visser JE, Giladi N. Falls and freezing of gait in Parkinson’s disease: a review of two interconnected, episodic phenomena. Movement Disord. 2004; 19: 871-884.
5. Peterson DS, King LA, Cohen RG, Horak FB. Cognitive Contributions to Freezing of Gait in Parkinson Disease: Implications for Physical Rehabilitation Phys Ther, 2016; May; 96: 659–670.
6. Zhang H, Yin X, Ouyang Z. A prospective study of freezing of gait with early Parkinson disease in Chinese patients. Medicine. 2016; 95:26-34.
7. Skripkina NA, Levin OS. Freezing of gait in patients with Parkinson’s disease. Zh Nevrol Psikhiatr Im S S Korsakova. 2014;6:41-48.
8. Young WR, Shreve L, Quinn EJ, Craig C, Bronte-Stewart H. Auditory cueing in Parkinson’s patients with freezing of gait.What matters most:Action-relevance or cue-continuity? Neuropsychologia. 2016; 87:54-62.
9. Nutt JG, Bloem BR, Giladi N, Hallett M, Horak FB, Nieuwboer A. Freezing of gait: moving forward on a mysterious clinical phenomenon. The Lancet Neurology. 2011;10:734-744.
10. Bloem BR, Housdorff JM, Visser JE, Gladi N. Falls and freezing of gait in Parkinson’s disease: a review of two interconnected, episodic phenomena. Movement Disorders. 2004;19:871-84.
11. Hoehn MM, Yahr MD. Parkinsonizm: onset, progression and mortality. Neurology 1967;17:427-42.
12. Goetz CG, Tilley BC, Shaftman SR. Movement Disorder Society UPDRS Revision Task Force. Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results. Movement Disord. 2008; 15:2129-2170.
13. Coste CA, Sijobert B, Pissard-Gibollet R, Pasquier M, Espiau B, Geny C. Detection of freezing of gait in Parkinson disease: preliminary results. Sensors (Basel). 2014;15;14:6819-6827.
14. Beaulne-Séguin Z, Nantel J. Conflicting and non-conflicting visual cues lead to error in gait initiation and gait inhibition in individuals with freezing of gait. Gait Posture 2016;49:443-447.
15. Lieberman A, Deep A, Dhall R, Tran A, Liu M. Early freezing of gait: Atypical versus typical Parkinson disoders. Parkinson’s disease. 2015; 2:1-5.
16. Vogler A, Janssens J, Nyffeler T, Bohlhalter S, Vanbellingen T. German Translation and Validation of the “ Freezing of Gait Questionnaire” in patients with Parkinson’s disease. Parkinson’s disease. 2015;1:1-5.
17. Tolleson CM, Dobolyi D, Romana OC. Dysrhythmia of Timed Movements in Parkinson’s disease and Freezing of Gait. Brain Res. 2015; 1624: 222–231.
18. Duncan RP, Leddy AL, Cavanaugh JT. Balance Differences in People with Parkinson Disease with and without Freezing of Gait. Gait Posture. 2015; 42: 306–309.
19. Moncini M, Carlson-Kuhta, Zampieri C, Nutt JG, Chiari L, Horak FB. Postural Sway as a marker of progression in Parkinson’s disease: A pilot longitudinal study. Gait Posture.2012; 36: 471-76.
20. Nonnekes J, Dam D, Nijhuis LB. Start React effects support different pathophysiological mechanisms underlying freezing of gait and postural instability in Parkinson’s disease. Plos One. 2015; 10:371-382.
21. Perez-Lloret S, Negre-Pages L, Damier P. Prevalence, determinants, and effect on quality of life of freezing of gait in Parkinson disease. JAMA Neurol. 2014; 1:884-890.
22. Hulbert S, Ashburn A, Robert L, Verheyden G. A narrative review of turning deficits in people with Parkinson’s disease. Disabil Rehabil, 2015; 37:1382-1389.
23. Akram S, Frank JS, Jog M. Parkinson’s disease and segmental coordination during turning: II. Walking turns. Can J Neurol Sci, 2013; 4:520-526.
24. Villadoniga M, San Millan A, Cabanes-Martinez L, Aviles-Olmos I, Del Alamo-De Pedro M, Regidor I. Quantitative gait analysis in patients with advanced Parkinson’s disease. Rev Neurol, 2016; 63:97-110.
25. Castagna A, Frittoli S, Ferrarin M et al. Quantitative gait analysis in parkinson’s disease: Possible role of dystonia. Movement Disord, 2016; 31:1720-1728.
26. Sofuwa O, Nieuwbaer A, Desloover K, Willems A, Chowet F, Jonkers L. Quantitative gait analysis in Parkinson’s disease: comparison with a healthy control group. Arch Phys Med and Rehab 2005; 86:1007-1013.