Research Article of Journal of Herbal Medicine Research
Intrinsic activity of aqueous leaf extract of Cymbopogon citratus against plasmodium-mediated tropical disease
Prof. Dr. Maher ALMOKDAD
Department of Medical Biochemistry, Faculty of Medicine, Gaziantep University Gaziantep, Turkey.
Mail address: Üniversite Bulvarı 27310 Şehitkamil, Gaziantep, Turkey.
Diabetes mellitus (DM) is one of the most common metabolic disorders that causes micro- and macro-vascular complication. The aim of this study was to evaluate The effects of cinnamon on fasting blood glucose (FBG), triglyceride (TG), total cholesterol (TC), and low density lipoprotein (LDL) in Syrian individuals with type 2 diabetes mellitus (T2DM). A total of 90 patients with type 2 diabetes (T2D), were randomized into two groups: one for placebo and one for treatment with cinnamon powder (Cinnamomum cassia), in daily amounts of 2 grams. We measured the patients’ blood glucose and lipid levels under fasting conditions at the beginning of the study, and again at 30 days, the end of treatment. The mean value of FBG level on the starting day before cinnamon intake was found to be 176.8 ± 9.6 mg/dl, and the mean values for lipids were TG 183.5 ± 15.5 mg/dl, TC 209.4 ± 7.8 mg/dl and LDL 119.4 ± 5.8 mg/dl. When diabetic patients were treated with the dose of 2 g cinnamon for 30 days, their mean FBG level dropped to 147.4 ± 8.9 mg/dl, TG 135.7 ± 9.6 mg/dl, TC 149.3 ± 8.6 mg/dl and LDL to 74 ± 6.2 mg/dl. No significant changes were noted in the placebo groups. The results of this study indicate that intake of 2 grams of cinnamon per day reduces serum glucose, TG, TC, and LDL and thus reducing the risk of diabetic complications.
Keywords: type 2 diabetes mellitus; fasting blood glucose; lipids; cinnamon