Research Article of Journal of Stroke Research
Histopathological Changes Of Cerebral Vessels Secondary To Drug Abuse
Zogopoulos Panagiotis, Theocharis Stamatios, Kotakidis Nikolaos, Patsouris Efstratios, Agapitos Emmanouel
First Department of Pathology, Medical School, National and Kapodistrian University of Athens, Greece
Drug abuse has been associated with a number of cerebrovascular adverse effects, such as hemorrhagic and ischemic stroke. Heroin, cocaine and amphetamines are the most commonly abused substances but a systematic pathology study of their effects on human cerebral vessels has not been conducted to date. We present a post-mortem, comparative, pathology study on the brains of drug addicts and healthy controls. The aim of this study was to determine the pathological changes of the vascular lumen, vascular wall and perivascular areas observed in the post-mortem brain of drug addicts compared to those of non-drug addicts healthy controls.
Keywords: drug abuse, vascular changes, brain, pathology