Welcome Dr Rodrigues to International Journal of Food and Nutrition Research

Dr Rodney Alexandre Ferreira Rodrigues
Universidade Estadual de Campinas, Centro Pluridisciplinar de Pesquisas Químicas e Biológicas

Biography & Research Interest

Welcome Dr Rodney Alexandre Ferreira Rodrigues to Join the Editorial Board of International Journal of Food and Nutrition Research.

Bachelor at Pharmacy at Sao Paulo University (1986), Master/ PhD at Food Technology at Campinas State University (1999/2004). Has experience in Chemistry, focusing on Chemistry of the Natural Products, acting on the following subjects: phytochemistry, medicinal plants, extration and microencapsulation.

Research Projects
2015 – Present
Development and evaluation of topical formulations for oral mucositis treatment containing Spilanthol Description: Spilanthol or afinin is an alkylamide found in herbs, among them, Spilanthes acmella (L.) L., and have several pharmacological properties such as anti-inflammatory, anesthetic and antioxidant activities. These properties may be of great interest in the treatment of oral mucositis, a typical side effect due to the treatment of cancer patients undergoing radiation and chemotherapy. The aim of this work is to obtain oral formulations to combat mucositis, with the incorporation of spilanthol obtained by supercritical extraction and evaluate their antiinflammatory activity through experimental models. For this purpose different bioadhesives will be selected to choose the most suitable for oral use, with properties such as flexibility, elasticity, color, taste and controlled release of spilanthol, that can bring comfort to the patient by avoiding the frequent change. Experiments in vitro and also anti-inflammatory and antinociceptive activities in vivo models of paw edema induced by carrageenan and gastrointestinal mucositis with subsequent histopathological analysis will also be performed. Participant Students: Specialization ( 1) / Master’s (1) Ph.D. ( 1) . Sponsor: FAPESP Fundação de Amparo à Pesquisa do Estado de São Paulo

2013 – 2015
Sisal waste and microorganisms for management panama disease and nematoses culture of banana Description: Project proposes the development of Trichoderma formulations, rhizobacteria and liquid waste sisal formulations (Agave sisalana) for ill-Panama control and nematoses banana .
2012 – 2014
Polymeric microparticles containing essential oil of Eucalyptus: analytical development for quantification of the major component Description: Essential oils are one of natural products being volatile substances extracted from plants, and some have been recognized as potential alternatives to synthetic commercial products as they are generally recognized as safe by the US FDA, and are used in many products such as artificial flavorings, fragrances formulations and expectorants, decongestants, external analgesics and antiseptics. Generally obtained by steam distillation , can suffer different decomposition processes during storage or handling. Thus, this protection is crucial to maintain their therapeutic action. This protection can be obtained through the formation of microparticles, whose production involves the use of polymers that minimize the deteriorative reactions. Eucalyptus is certainly the most widely planted kind in the world. In trade there are three most common species: E. citriodora, E. Eucaliptus. The citronellal is the main component of E. citriodora oil, since the 1,8-cineole is the major compound of E. globulus. The large production of eucalyptus in Brazil today is focused on the wood industry, but the discovery of alternative sources of use of essential oils of certain species could boost the market or indicate a more profitable exploitation of this activity with the creation of new jobs. .

2012 – 2014
Nigeria antimalarial formulations: Transdermal delivery of artemether-based combination drug through patches and clinical evaluation of its efficacy and safety in treating uncomplicated malaria produced from A. annua crops Description: Malaria has been and remains one of the greatest sources of misery known to man. It is a serious disease caused by the parasite Plasmodium falciparum, and threatens about 3.2 billion people in 107 countries in different parts of the world even though the worst prevalence is seen in sub-Saharan Africa, where it is the highest cause of morbidity and mortality accounting for over a million deaths each year. Unfortunately, more than 90% of these cases are children under 5 years (WHO). Transdermal therapeutic patches impregnated with only a little quantity of artemether were shown in these investigations to be very effective in the treatment of uncomplicated malaria in animal models. The studies demonstrated that, usually, a single patch (containing 10% of the amount of artemether required in oral medication), which only needs to be affixed to the skin of the animal for 5 days is adequate for complete clearance of parasitaemia in mice infected with Plasmodium without side effects. Building on the successes of these preliminary studies, our interest in the project proposed herein is to investigate the use of transdermal patches to deliver artemether and study the pharmacodynamic responses in vivo in humans. Participant Students: Specialization ( 1) / Professional Master Studies ( 1) / Ph.D. ( 1) . Sponsor: CNPq Conselho Nacional de Desenvolvimento Científico e Tecnológico .

2012 – 2014
Nanostructured lipid systems (liposomes and nanoemulsions) encapsulating the essential oil of oregano (Origanum vulgare): production, characterization and microbial activity.

2011 – 2013
Review monographs medicinal plants and interlaboratory evaluation for the Brazilian Pharmacopeia. 2011 – 2013 Microparticles of cashew gum and essential oils of Cordia verbenacea d. c. and Achyrocline satureioides (LAM.) D. C: anti-inflammatory evaluation and analytical development for quantification of ±-humulene, ±-pinene and (-)- trans-caryophyllene Description: Cashew gum represents an abundant raw material in Brazil, a raw material able to replace the traditionally Arabic gum from Africa. To analyze the constituents of the oils in the microparticles will be held release polymeric complex which can be done in water once the gum is soluble, and using the gas chromatography ionization detector flame (GC / FID) via headspace in a sealed bottle, the method should be validated. It will also assessed the stability of the original material, and this after microparticulation, keeping them in climate camera with controlled temperature and humidity, along with monitoring of anti-inflammatory activity during the course of time. It is expected to decreased deterioration of oil constituents exposed to external agents and cited the extension of the biological action of the microparticles.


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