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The clitoris in the chromosomes, and immunity – an essay

Review article of Global Journal of Men’s Health The clitoris in the chromosomes, and immunity – an essay Florent Pirot Independent researcher. This paper underlines scientific arguments on the clitoris’ contribution to health and to immunity in particular. Sexology misses key elements that reduce the sexual abilities of men, and it tries to bridge the gap with simple arguments, chromosomal and biophysical. Keywords: Sexology, Public health, Immunity, Respiratory diseases ...

FOOT AND ANKLE CHARACTERISTICS IN GOUT: A SYSTEMATIC REVIEW

Review Article of American Journal of Orthopedic Research and Reviews Foot and Ankle Characteristics in Gout: A Systematic Review Kerry Bendell1 MSc, Brunilda Agalliu2 BSc(Hons), Simon Otter2,3* PhD 1Podiatry Department Sussex Community NHS Foundation Trust, Durrington Health Center, BN13 2RX 2School of Sport & Health Science, University of Brighton, 49 Darley Rd, Eastbourne, BN20 7UR, UK 3Centre for Regenerative Medicine and Devices, University of Brighton, Lewes Rd, Brighton, BN2 4AT Objectives: Gout has a predilection for the foot and ankle, but the impact of gout has limited presence in the literature. The aim of this systematic review was to synthesise existing literature which has investigated the characteristics of foot and ankle involvement in gout; identifying consensus and highlighting areas for further study. Methods: Studies were included if they were published in English and involved participants over 18 years of age with gout, and presented original findings relating to outcome measures associated with the foot and ankle. Methodological quality was assessed using a modified version of the Quality Index Tool. Results. Of 707 studies identified, 16 met the inclusion criteria and were included in this review. The mean (range) quality score was 68.1% (38.9%-88.9%). Compared to controls, participants with gout reported higher levels of activity limitation, foot-related pain and disability and walked more slowly. Plain radiography, dual-energy Computer Tomography and diagnostic ultrasound consistently demonstrated pathological features of gout in the first metatarsophalangeal joint and Achilles tendon. However, studies offered limited quality, particularly around recruitment strategies, validity and potential impact of confounding factors, making definitive statements difficult. Conclusions: This systematic review highlights the negative impact of gout on the structure and function of the foot and ankle causing significant impairment and disability. To effectively guide management, improvements in methodological quality are recommended. Keywords: Gout, Foot, Ankle ...

Cardiac Metastatic Involvement in Lung Cancer – Cardiac Metastatic Involvement

Case Report of International Journal of Case Reports Cardiac Metastatic Involvement in Lung Cancer - Cardiac Metastatic Involvement Miguel Borregón1*, Katherine Martínez2, Alba Ramos1, Irene Ramos1, Beatriz Berzal1, Manuel Mazariegos1, Margarita Díez1, Cristina Gómez1, Ana Belén Rupérez1, Irene Otero1, Ana Karina Santos1, Juan David Cárdenas1, Elia Martínez3 1Medical oncology service. Hospital Virgen de la Salud de Toledo, Spain; 2Medical oncology service. Hospital General de Segovia, Spain; 3Medical oncology service. Hospital Universitario de Fuenlabrada, Spain. Lung cancer is the second most common solid tumour and the first in mortality worldwide. Important progress has been reached in recent years in this pathology, focusing its treatment on histology, molecular biology and clinical presentation. Cardiac metastatic involvement consists in a severe clinical entity with increasing incidence due to better radiological techniques and longer survival of lung cancer. It requires special care and attention from many specialists. Clinical review about cardiac involvement secondary to lung cancer is provided, focused on its epidemiology, clinical presentation, diagnoses and treatment. Better understanding about cancer natural history is needed to offer the best treatment and care. Condensed abstract Cardiac metastatic involvement consists in a severe clinical entity with increasing incidence due to better radiological techniques and longer survival of lung cancer. It requires special care and attention from many specialists. Clinical review about cardiac involvement secondary to lung cancer is provided, focused on its epidemiology, clinical presentation, diagnoses and treatment. Keywords: Lung cancer, Heart metastases, Malignant pericardial effusion, Cardiac tamponade ...

Successful surgical management of chronic bilateral encapsulated seroma after node-negative breast cancer: A Case Report

Case Report of International Journal of Case Reports Successful surgical management of chronic bilateral encapsulated seroma after node-negative breast cancer: A Case Report Kjersti Fosheim1*, Sophie Bojesen2, Hannah Troestrup2 and Anne-Vibeke Laenkholm1 1Department of Surgical Pathology, Zealand University Hospital, Roskilde, Denmark. 2Department of Plastic Surgery, Zealand University Hospital, Roskilde, Denmark. Background: Chronic encapsulated seroma following breast cancer surgery is a rare entity, and management is challenging. We present clinical and pathologic findings in a patient with extensive history of bilateral refractory breast seroma successfully treated with capsulectomy. Case presentation: A 71-year-old woman with previous early BRCA2 associated, node-negative breast cancer, developed late onset seroma following endocrine therapy, unilateral breast-conserving surgery, and completion of adjuvant radiotherapy. Non-simultaneous bilateral mastectomy was later performed to treat infection and reduce risk of contralateral breast cancer. Each surgery was followed by chronic seroma. After six years of ineffective treatment attempts with repeated aspirations, the patient successfully underwent bilateral capsulectomy. She remains seroma-free nine months from time of capsulectomy. Conclusion: This is the first report of late onset bilateral encapsulated breast seroma following mastectomy without axillary dissection. When managing breast seroma refractory to conventional treatment encapsulated seroma and prompt capsulectomy should be considered. Keywords: Breast cancer, encapsulated seroma, capsulectomy, case report ...

Unexpected Combined Double Posterior and Anterior Approach to Treat Thoracic Disc Herniation: a Case Report

Case Report of International Journal of Case Reports Unexpected Combined Double Posterior and Anterior Approach to Treat Thoracic Disc Herniation: a Case Report MARÍA CARMEN VIEJOBUENO-MAYORDOMO M.D., ANA VERDEJO-GONZÁLEZ M.D., DAVID RUIZ PICAZO M.D., JOSÉ RAMÍREZ-VILLAESCUSA* Ph.D. DEPARTMENT OF ORTHOPAEDIC SURGERY, SPINE UNIT. COMPLEJO HOSPITALARIO UNIVERSITARIO DE ALBACETE, SPAIN. Introduction: Although frequently observed in magnetic resonance images, symptomatic thoracic disc herniations are rare. Surgical treatment is indicated when patients suffer from functional symptoms with no response to medical treatment, when neurologic symptoms appear or worsen or in the event of myelopathy. Posterolateral approaches are commonly accepted as the treatment for lateral and mediolateral disc herniations and non-calcified medial herniations. On the other hand, anterior approaches have been accepted to treat gigantic calcified medial disc herniations. Case presentation: This case report presents on a 57-year-old female patient suffering from thoracolumbar pain and impairment. The magnetic resonance study showed images compatible with a posteromedial T12-L1 disc herniation that, after medical treatment failure, required surgical treatment. Initially, a posterior approach was performed, resulting in the immediate postoperative period in motor and sensitive deficit of the lower left limb, so a surgical reintervention was performed using an anterior approach, obtaining good clinical and functional results. Conclusion: Thoracic disc herniations are uncommon. Surgical indication is decided in the presence of neurologic symptoms. Neurologic injury is a common complication due to the lesion’s characteristics and it can also be secondary to the surgical procedure. An adequate election of the surgical approach may minimize neurologic injuries. Keywords: Case Reports, Intervertebral Disc Degeneration, Orthopedic Procedures, Spinal Cord Injury, Spine ...

Celiac disease presenting as abnormal atrial rhythm resolving after gluten-free diet

Case Report of International Journal of Case Reports Celiac disease presenting as abnormal atrial rhythm resolving after gluten-free diet Moshe Rav-Acha1,3 MD, Eyal Shteyer2,3* MD 1Cardiology, Shaare Zedek Hospital, Hebrew University, Jerusalem; 2Pediatric Gastroenterology, Shaare Zedek Hospital, Hebrew University, Jerusalem; 3Faculty of Medicine, Hebrew University of Jerusalem, Israel. We describe a case of a teenager who presented with palpitations and abnormal low atrial rhythm. Celiac Disease (CD) serology, sent due to low ferritin, was positive and gastroscopy confirmed CD diagnosis. Both palpitations and abnormal rhythm resolved after gluten-free diet with normalization of CD serology. Keywords: celiac disease, arrhythmia, gluten-free diet ...