Synthesis of Bicyclic Adduct through Regioselective Baeyer-Villager oxidation

Synthesis of Bicyclic Adduct through Regioselective Baeyer-Villager oxidation

Bello Y. Makama* and Wahidullah Azizi

Division of Mathematics, Sciences & Technology, American University of Afghanistan, Darul-Amman, Kabul, Afghanistan

American journal of chemical research-2d-code

Baeyer-Villager oxidation reaction has become accepted as a right approach in the ring expansions for the preparation of both bicyclic and tricyclic lacotnes; however, successful application of the regioselective Bayer-Villager oxidation protocol to the synthesis of particularly congested scaffolds remains distinctly tricky. Herein the Baeyer–Villiger oxidation of Bicyclo[3.2.0]hept-3-ene-6-one is studied with oxygen insertion leading to the functionalized oxabicyclic adduct with complete regioselectivity.

Keywords: bicyclic adduct, regioselectivity, Bayer Villager oxidation, synthesis

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How to cite this article:
Bello Y. Makama and Wahidullah Azizi. Synthesis of Bicyclic Adduct through Regioselective Baeyer-Villager oxidation. American Journal of Chemical Research, 2018, 2:9. DOI: 10.28933/ajcr-2018-11-1208

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