Review on the flow injection analysis (FIA)

Review on the flow injection analysis (FIA)

Abraha Gebregewergis

Ethiopian Institute of Agricultural Research, Kulumsa Agricultural Research Center

Flow injection analysis (FIA) is a simple and versatile analytical technology for automating wet chemical analysis, based on the physical and chemical manipulation of a dispersed sample zone formed from the injection of the sample into a flowing carrier stream and detection downstream.
Flow injection analysis is highly efficient technique for the automated analyses of samples. Unlike the centrifugal analyzer, in which the number of samples is limited by the transfer disk’s size, FIA allows for the rapid, sequential analysis of an unlimited number of samples. FIA is one example of a continuous-flow analyzer, in which we sequentially introduce samples at regular intervals into a liquid carrier stream that transports them to the detector.
The principle is similar to that of segmented flow analysis (SFA) but no air is injected into the sample or reagent streams. FIA is computer compatible and allows automated handling of sample and reagent solutions with a strict control of reaction conditions. FIA is an automated method of chemical analysis in which a sample is injected into a flowing carrier solution that mixes with reagents before reaching a detector.
Unlike chromatography, however, flow injection analysis is not a separation technique. Because all components in a sample move with the carrier stream’s flow rate, it is possible to introduce a second sample before the first sample reaches the detector. As a result, flow injection analysis is ideally suited for the rapid throughput of samples. FIA is a general solution-handling technique, applicable to a variety of tasks ranging from pH or conductivity measurement to colorimetry, titrations and enzymatic assays.

Keywords: Carrier; Detector; Diffusion; Dispersion; Flow injection; Versatile

Free Full-text PDF

How to cite this article:
Abraha Gebregewergis.Review on the flow injection analysis (FIA). American Journal of Scientific Research and Essays, 2021,6:4.

1. Christian, G. D. (1994). Analytical Chemistry, 5th ed.; John Wiley & Sons: New York, pp 593–600.
2. Karlberg, B.; Pacey, G. E.(1989). Flow Injection Analysis. A Practical Guide; Elsevier: Amsterdam.
3. Ruzicka, J.; Hansen, E. H. (1988). Flow Injection Analysis, 2nd ed., John Wiley & Sons: New York.
4. Skoog, D. A.; Holler, F. J.; Nieman, T. (1998). A Principles of Instrumental Analysis, 5th ed.; Saunders College: Philadelphia, pp 829–840.
5. Valcárcel, M.; Luque de Castro, M. D. (1987). Flow Injection Analysis: Principles and Practice, Ellis Horwood: Chichester, England.
6. Vander Linden, W. E. (1994). Pure and Applied Chemistry, 66, 2493.

Terms of Use/Privacy Policy/ Disclaimer/ Other Policies:
You agree that by using our site, you have read, understood, and agreed to be bound by all of our terms of use/privacy policy/ disclaimer/ other policies (click here for details)

CC BY 4.0
This work and its PDF file(s) are licensed under a Creative Commons Attribution 4.0 International License.