American Journal of Basic and Applied Sciences


Optimization of overhaul of EMU Based on Planning Model

Research Article of American Journal of Basic and Applied Sciences Optimization of overhaul of EMU Based on Planning Model Yu Cao1*, Hairui Zhang1, Zhong Zheng2 1College of Science, China Three Gorges University, Yichang, 443002, China. 2College of Electrical Engineering & New Energy, China Three Gorges University, Yichang 443002, China. With the speed increase of the railway and the construction of the passenger dedicated line, the application efficiency and maintenance quality of the EMU, as the main means of transport of the passenger dedicated line, are directly related to the safe operation of the passenger dedicated line. Therefore, it is very necessary to carry out high-efficiency and high-quality maintenance work for EMU. In this paper, the maintenance problem of EMU is studied. According to the different maintenance process of EMU under different conditions, a mixed nonlinear programming model is established, and the software is used to solve the shortest total time of maintenance of all EMU is 541 min. The model provides a reference for the optimization of maintenance of EMU in actual production and life, and is helpful to improve the maintenance efficiency of EMU. Keywords:Overhaul of EMU; Mixed nonlinear programming model; Genetic algorithm ...

COMPLIANCE AND DOSAGE FORM PREFERENCE IN IRON/ FOLIC ACID SUPPLEMENTATION IN ANTENATAL CARE MOTHERS

Research Article of American Journal of Basic and Applied Sciences COMPLIANCE AND DOSAGE FORM PREFERENCE IN IRON/ FOLIC ACID SUPPLEMENTATION IN ANTENATAL CARE MOTHERS, AYDER COMPREHENSIVE SPECIALIZED HOSPITAL, NORTHERN ETHIOPIA: A CROSS SECTIONAL STUDY Teshome Abegaz, Arega Gashaw School of Public health, Mekelle University Background: Globally, iron deficiency anaemia is one of the major health problems of pregnant women. Less than one percent took iron supplements during their last pregnancy, and the major problem with iron-folate supplementation during pregnancy is non-compliance. Objective: The aim of this study is to assess prevalence of Compliance and Dosage Form Preference in Iron folic acid supplementation (IFAS) in Antenatal Care (ANC) visit others, Ayder Comprehensive Specialized Hospital, Ethiopia. Methods: A cross sectional study was conducted at Ayder comprehensive specialized hospital antenatal care from Oct.2018 – Feb.2019. Result: The total number of study participants was 278 and 172 (63.3 %) were in compliance with iron / folic acid supplementation. The five associated variables indicated significant association at 95% confidence interval for compliance to iron/folic acid supplementation was, age less than 28 years AOR=.044, [.015-.128] , a monthly income AOR=10.304, [3.220-32.970] family size AOR=.144 [.036-.565], four and more ANC visits AOR=4.193, [1.689-10.411, first trimesters and second trimester AOR=21.168, [6.297-71.158] and AOR=4.458, [1.592-12.485] , AOR=4.193, [1.689-10.411] all with p value < 0.05. Conclusion: In this study, compliance with prenatal iron folate supplementation remains very poor as 63.3%. Mother’s age, monthly income, number of ANC visits, family size and trimesters have been found to be significantly correlated with compliance during pregnancy with prenatal iron foliate supplementation. Therefore, during the ANC visit health workers and health extension workers must regularly advise on IFAS benefits to strengthen adherence to IFAS during current and future pregnancies. For the implementation and refinement of iron supplementation program strategies and acceptable dosage forms, more ...

Using Multi-constraint Integer Nonlinear Optimization Model to Select Generator

Research Article of American Journal of Basic and Applied Sciences Using Multi-constraint Integer Nonlinear Optimization Model to Select Generator Rui Yan1*, Zihan Hu1, Cheng Li1, Lijuan Li2, Rao Fu1 1College of Hydraulic & Environmental Engineering, China Three Gorges University, Yichang, 443002, China. 2College of Medicine, China Three Gorges University, Yichang, 443002, China. This paper studies the power generation plan when the power is cut off within a week in the factory. Considering various factors that affect the cost, it comprehensively analyzes the possibility of opening the plan and the influence of three kinds of costs on the total cost, and establishes a multi-constraint integer nonlinear optimization model. In order to minimize the total cost of a week, a minimum model of fixed cost, marginal cost and start-up cost was established, and a seven-day minimum cost scheme was obtained by means of dynamic programming.After changing the output power of the generator, the constraint conditions of the output power are adjusted based on the model of the above problems, and a new model of electricity demand and generation is obtained.In this paper, the model is extended to other problems of continuous segmentation, and the improvement can be generalized to solve such problems. Keywords: Multi-constrained integer nonlinear combination optimization method; Start-up cost; Power dispatch;lingo ...

DRUG INDUCED HEPATOTOXICITY AMONG TB AND TB/HIV CO-INFECTED PATIENTS

Research Article of American Journal of Basic and Applied Sciences DRUG INDUCED HEPATOTOXICITY AMONG TB AND TB/HIV CO-INFECTED PATIENTS IN AYDER COMPREHENSIVE SPECIALIZED HOSPITAL, TIGRAY, ETHIOPIA Arega Gashaw and Afewerk Tesfay School of Pharmacy, Mekelle University Background: Drug-induced hepatotoxicity is the most prevalent side effect that lead to the failure of new drug candidates or withdrawal from the market and is a significant clinical problem that contributes more than 50% of acute liver failure. Objective: The objective of this study is to assess the prevalence and associated risk factors of drug-induced hepatotoxicity among TB or TB/HIV co-infected patients in ACSH, Mekelle, Ethiopia. Method: A retrospective cross sectional method was conducted in ACSH on the prevalence and associated risk factors of drug-induced hepatotoxicity among TB or TB/HIV co-infected patients from January to April 2019 E.C. Result: Out of 164 participants, 16 of them had developed hepatotoxicity. After bivariate logistic regression analysis, Predictor variables with p-value < 0.25 by bivariate analysis were analysed using multivariable logistic regression analysis and Art regimen [AOR=0.038, (CI95%) (0.002-0.846); p=0.038], CD4 count less than 50 [AOR=0.031, (CI95%) (0.00-0.64); p=0.08] and disseminated of TB [AOR=0.042, (CI95%) (0.001-0.88); p=0.030] as independent predictors of drug induced hepatotoxicity. Conclusion: The prevalence of DIH was 9.8 %. Results suggest that in the presence of disseminated pulmonary TB and CD4 count in HIV positive patients and those who are on Efavirenz based ART medication should be closely monitored for the occurrence of hepatotoxicity to prevent morbidity and mortality. Keywords: Tuberculosis, Drug induced hepatotoxicity, Risk factor, CD4, ART ...

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American Journal of Basic and Applied Sciences

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