American Journal of Cancer Research and Reviews


Review Article of American Journal of Cancer Research and Reviews BREAST CANCER – REVIEWS Effiong Edet Bassey Department of Applied Microbiology and Brewing, Nnamdi Azikiwe University, Awka-Nigeria Breast cancer is the type of cancer that affects the breast. It is the most common invasive cancer in women. The incidence of breast cancer varies greatly around the world. It is lowest in less-developed countries and greatest in the more-developed countries. Types of breast cancers, Ductal carcinoma begins in the milk duct and is the most common type, labular carcinoma starts in the lobules, invasive breast cancer start when cancer cells break out from inside the lobules or duct and invade nearby tissue increasing to other parts of the body, while non-invasive is when the cancer is still inside its place of origin and has not broken out the first symptoms of the breast cancer are usually an area of thickened tissue in the breast or a lump in the breast or in an armpit. The risk factors are, age, genetics, devise breast tissue eg Estrogen exposure and breast feeding, body weight, Alcohol consumption, Hormone treatment and radiation exposures. Diagnosis often occurs as a result of routine screening. Breast Examination, Imaging Tests, Biopsy, Radiation therapy, Sentinel node, Mastectomy and Lumpectomy. Treatment depends in types of breast cancer, stage of the cancer and sensitive of hormones: Eg Hormone blocking chemotherapy and surgery. Prevention based on avoiding excess alcohol, getting enough exercise, keeping healthy mess index and taking fresh fruits and vegetables. Good lifestyle is recommended E.g diet, exercise and weight loss recommend. Keywords:Breast, cancer, Risk factors, diagnosis, treatment ...

To Estimate the level of Oxidative stress parameter among Diabetic persons with Squamous cell carcinoma of oral cavity: A Case Control Study

Research Article of American Journal of Cancer Research and Reviews To Estimate the level of Oxidative stress parameter among Diabetic persons with Squamous cell carcinoma of oral cavity: A Case Control Study Shashidhar K.N, Harshith Gowda KB, Munilakshmi. U, Hemalatha. A, Vinay Babu. S Sri Devaraj Urs Medical College, Kolar, Karnataka, India Background: Diabetes mellitus and cancer share common modifiable and non- modifiable risk factors. Both conditions have a great impact on social and economic status of an individual and their families. Diabetes is rapidly becoming a common metabolic problem in rural populations. At the same time, the incidence of oral cancer has not decreased over the years despite exhaustive research and has become the most common cause of death. Oral cancer accounts for approximately 4-5% of all cancers in the world. Recent epidemiological studies have shown a strong link between diabetes and cancer. Objective: To Estimate the concentration of Oxidative stress markers among Diabetic persons with Squamous cell carcinoma of oral cavity .Materials and Methods: A Case Control study, conducted at Sri Devaraj Urs Medical College attached to Sri R.L. Jalappa Hospital a constituent of Sri Devaraj Urs Academy of Higher Education and Research, Kolar. A total of 60 subjects were included in the study and categorised into equal number of cases and controls. Diabetic and lipid profiles were estimated by enzymatic methods in Dry chemistry Autoanalyser, Vitros 5.1FS, HbA1c analysed by HPLC (BioRad D10 USA), Nitric Oxide, Malondialdehyde, and Vitamin C by spectrophotometer Perkin Elmer UV/ VIS Lambda-35 methods respectively. Results: Our patients were in the age group of 30- 80 years with a mean age of 52.62± 12.67. Diabetic profile and oxidant markers were significantly elevated in cases compared to controls. However, mean values of lipid profile and antioxidants were significantly reduced in cases with an exception ...

Recurrent gliomas- a short review of literature.

Review Article of American Journal of Cancer Research and Reviews Recurrent gliomas- a short review of literature. Dr. Sudeb Mukherjee MBBS. MD.(Medicine), DM-Post Doctorate Fellow-ICVS, IPGME&R, Kolkata-700020. Gliomas one of the commonest tumour account for 40-60% of all primary neoplasm of the central nervous system. Very little is known about pathological changes associated with recurrence of gliomas. Histlogical changes regarding this transformation also is not well documented. Effect of radiotherapy and chemotherapy which results in decrease in cellularity, fibrosis, thickening of vessels are also not well documented. Paired study combining both primary and recurrent gliomas are sparse. Several genetic alterations has been mentioned in the causation and pathophysiology of recurrent gliomas. Starting from overexpression to mutation of p53 to Epidermal Growth Factor(EGFR), platelet derived growth factor-α(PDGF-A),PTEN , MDM2 all have mentioned several studies. This review article describes every aspects of recurrent gliomas in short span. Keywords: Recurrent gliomas, EGFR( Epidermal Growth Factor), p 53, platelet derived growth factor-α(PDGF-A) ...

Trace Element Contents in Thyroid Cancer Investigated by Energy Dispersive X-Ray Fluorescent Analysis

Research Article of American Journal of Cancer Research and Reviews Trace Element Contents in Thyroid Cancer Investigated by Energy Dispersive X-Ray Fluorescent Analysis ZAICHICK Vladimir1 and ZAICHICK Sofia2 1 Radionuclide Diagnostics Department, Medical Radiological Research Centre, Russia 2 Laboratory of Dr. Gabriela Caraveo Piso, Feinberg School of Medicine, Northwestern University, USA Background: Thyroid cancer is an internationally important health problem. The aim of this exploratory study was to evaluate whether significant changes in the thyroid tissue levels of Br, Cu, Fe, Rb, Sr, and Zn exist in the malignantly transformed thyroid. Methods: Thyroid tissue levels of six trace elements (Br, Cu, Fe, Rb, Sr, and Zn) were prospectively evaluated in 41 patients with thyroid malignant tumors and 105 healthy inhabitants. Measurements were performed using 109Cd radionuclide-induced energy-dispersive X-ray fluorescent analysis Tissue samples were divided into two portions. One was used for morphological study while the other was intended for trace element analysis. Results: It was found that contents of Br, Cu, and Rb were significantly higher (approximately 10, 3.4, and 1.4 times, respectively) and content of Zn were slightly, but significantly, lower (25%) in cancerous tissues than in normal tissues. Conclusions: There are considerable changes in trace element contents in the malignantly transformed tissue of thyroid. Keywords: Thyroid malignant tumors - Intact thyroid - Trace elements - Energy-dispersive X-ray fluorescent analysis ...

Dr. Elsayed Ibrahim Elagamy
Professor of Immunology, Department of Applied Medical Sciences, College of Community (Unaizah), Qassim University, Kingdom of Saudi Arabia.

Dr. Indrasena R Kummetha
University of California San Diego (UCSD), Department of Pediatrics, 9500 Gilman Drive, MC 0762, BRF-11, Room NO:2220, San Diego, California, 92093, USA

Dr. Zhiqiang Hou
Senior Research Associate, Center for Alzheimer’s and Neurodegenerative Diseases, UT Southwestern Medical Center, Dallas, TX 75390

Dr. Nisar Haider Zaidi
MBBS, MS, MRCS (Glasgow), FICS, FACS. Department of surgery, King Abdulaziz University Hospital , POBox-80215 Jeddah 21589 , Saudi Arabia

Dr. Shahin Gavanji
Chairman of “WAMS National Council of Iran at World Academy of Medical Sciences (WAMS), Chairman WAMS Oncology Research Group of Iran, Young Researchers and Elite Club, Khorasgan Branch, Islamic Azad University, Khorasgan, Isfahan, Iran, Department of Biotechnology, Faculty of Advanced Sciences and Technologies, University of Isfahan, Isfahan, Iran.

Dr. Kabita Mishra
D.D.P.R.-Central Research Institute for Homoeopathy , (Ministry of A.Y.U.S.H., Government of India)

Dr. Prakash Prajapat
Assistant Professor, Department of Chemistry, Mehsana Urban Institute of Sciences, Ganpat University

Dr. Naoshad Muhammad
Department of Radiation Oncology, School of Medicine, Washington University in Saint Louis

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1.ZAICHICK Vladimir and ZAICHICK Sofia. Trace Element Contents in Thyroid Cancer Investigated by Energy Dispersive X-Ray Fluorescent Analysis. American Journal of Cancer Research and Reviews, 2018,2:5. DOI: 10.28933/ajocrr-2017-12-2801 
2.Kénémé Bineta; Ciss Daouda; Ka Sidy; Mbaye Fatimata; Dem Ahmadou; Sembène Mbacké. UTERINE FIBROIDS IN SENEGAL: POLYMORPHISM OF MED12 GENE AND CORRELATION WITH EPIDEMIOLOGICAL FACTORS. American Journal of Cancer Research and Reviews, 2018,2:4. DOI:10.28933/ajocrr-2017-12-2601 

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American Journal of Cancer Research and Reviews