American Journal of Dermatological Research and Reviews


Management of Oro-Cutaneous Manifestations in Behçet disease and Recurrent Oral Aphthosis, review article

Review Article of American Journal of Dermatological Research and Reviews Management of Oro-Cutaneous Manifestations in Behçet disease and Recurrent Oral Aphthosis, review article Khalifa E. Sharquie1, Fatema A. Al-Jaralla2 1Department of Dermatology, College of Medicine, University of Baghdad. Iraqi and Arab Board for Dermatology & Venereology, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq. 2Department of Dermatology, College of Medicine, University of Baghdad, Baghdad, Iraq. Recurrent oral aphthosis is a major health problem affecting 20% of population. Its pathogenesis is not well elucidated, however, it’s considered as part of major criteria of Behçet disease. Many therapies advised to manage these ulcerations in both diseases and most of them are symptomatic, however, in the last decades; some of them have shown therapeutic as well as prophylactic roles. Herein, we review the different aspects of these therapies with emphasis on Iraqi experience. Keywords: Recurrent oral aphthosis, Behçet disease, Management ...

The Effectiveness of Cream of Centella asiatica Ethanol Extract in Chitosan Nanoparticles Compared with Centella asiatica Ethanol Extract Cream, Silver Sulfadiazine Cream, and Control on Superficial Dermal Burn Healing in Rats

Research Article of American Journal of Dermatological Research and Reviews The Effectiveness of Cream of Centella asiatica Ethanol Extract in Chitosan Nanoparticles Compared with Centella asiatica Ethanol Extract Cream, Silver Sulfadiazine Cream, and Control on Superficial Dermal Burn Healing in Rats Fifinela Raissa, Kusmarinah Bramono, Sondang P. Sirait, Lia Damayanti, Rafika Indah Paramita Dermatology and Venereology Study Program, Faculty of Medicine, Universitas Indonesia Introduction: Centella asiatica extract is known to promote wound healing. Nowadays nanotechnology, especially nanoparticle is used to increase the bioavailability of active ingredients into the skin, one of which is chitosan nanoparticle. However, the effectiveness of Centella asiatica ethanol extract in chitosan nanoparticle (CAEECN) towards superficial dermal burn healing is not fully understood. Aim: To determine the effectiveness of CAEECN cream compared to Centella asiatica ethanol extract (CAEE) cream, silver sulfadiazine (SSD) cream and control in superficial dermis burn healing in Sprague-Dawley rats. Materials and Methods: A total of 20 male Sprague-Dawley rats were divided into 4 groups. After anesthetizing, 4 superficial dermis burns were made on the back of each rat and was given 4 treatments (CAEECN, CAEE, SSD, and control) afterward. Each group was sacrificed separately (respectively on day 3rd, 7th, 14th, and 21st post-burn induction). Several evaluations were macroscopic (wound size), and microscopic parameters (reepithelialization ratio and distance, wound contraction index, wound size, and angiogenesis). Results: There was no significant difference in wound size between treatments on day 0, 3, 7, 14, and 21. But three active agents (CAEECN, CAEE, and SSD) treated group showed early decrease of wound size compare to control group on day-3. Microscopically, there were no significant differences in reepithelialization ratio and distance, wound contraction index, wound size, angiogenesis. Nevertheless, CAEECN treated group showed the smallest wound size on day-3 and highest angiogenesis on day 21. Conclusion: Effectiveness of CAEECN ...

Volumeplasty of bulky nose using heat dermabrasion as a minor therapy

Research Article of American Journal of Dermatological Research and Reviews Volumeplasty of bulky nose using heat dermabrasion as a minor therapy Khalifa E. Sharquie1, Fatema A. Al-Jaralla2 1Department of Dermatology, College of Medicine, University of Baghdad. Iraqi and Arab Board for Dermatology & Venereology, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq. 2Department of Dermatology, College of Medicine, University of Baghdad, Baghdad, Iraq Background: Ultrathick nasal skin and nodulation is one of the most daunting challenges in cosmetic nasal surgery. Rhinoplasty is a common surgical procedure to correct mostly gross abnormal nasal anatomical variation; however, many patients have minor bizarre shape or deformities that could not be well corrected by ordinary surgical procedures. So we should find other techniques to correct these unwanted or undesired nose shape abnormalities. Objective: The purpose of this article is to perform heat dermabrasion to reduce the size of bulky nose and to create new alar groove and to remove nose nodulations, acne or traumatic scarring. Patients and methods: In this study, we collected 40 patients with bulky nose during the period from 2009 through 2019; 21 females and 19 males and their ages ranged from 20-65 years. An Informed consent was taken from each patient before starting the study, after full explanation about the procedure. All patients had bulky nose, some had nodulation of nose and acne or traumatic scarring. Only one patient had history rhinophyma of several years duration. All patients were treated with heat dermabrasion using diathermy needle after local xylocaine anesthesia and patients were received topical antiseptic and oral antibiotics to be seen after 2 weeks. Then topical corticosteroid was used to prevent post-inflammatory pigmentation. Results:A total of 40 patients diagnosed with bulky nose were enrolled in this study; 21 (52.5%) patients were females and 19 (47.5%) were males.  Age of patients ...

Trichotillomania is chronic obsessive compulsive disease with a diagnostic hair loss patterns

Research Article of American Journal of Dermatological Research and Reviews Trichotillomania is chronic obsessive compulsive disease with a diagnostic hair loss patterns Khalifa E. Sharquie1, Fatema A. Al-Jaralla2 1Department of Dermatology, College of Medicine, University of Baghdad. Iraqi and Arab Board for Dermatology & Venereology, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq. 2Department of Dermatology, College of Medicine, University of Baghdad , Baghdad, Iraq. Background: Trichotillomania (TTM) is a common cause of childhood alopecia. It’s a traumatic alopecia and is defined as the irresistible urge to pull out the hair, accompanied by a sense of relief after the hair has been plucked. The condition maybe episodic and the chronic type is difficult to treat. There seem to be an increase in the prevalence of the condition probably due to the changing life style into a more stressful one. Objective: To do full evaluation of this disease and description of  hair loss patterns. Patients and methods: In this descriptive study, we collected patients with trichotillomania who had attended department of dermatology, college of medicine, university of Baghdad, Baghdad teaching hospital during the period from 2011 through 2019 where 114 cases of TTM were seen. The diagnosis was established on clinical basis after exclusion of other dermatological diseases and medical problems.Full history was taken from each patient including demographic data, presence of stressful life event as a triggering factor. Psycholgical assessment was carried out for each patient by experienced dermatologist as psychiatric referral was refused by all patients and their families.Full description of patterns of hair loss was carried out after exclusion of other causes of hair loss especially alopecia areata. Results: A total of 114 patients diagnosed with TTM were enrolled in this study,88 (77.19%) patients were females and 26 (22.8%) males with female to male ratio: 3.38:1 . Age of ...

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American Journal of Dermatological Research and Reviews (ISSN:2638-1893; DOI:10.28933/AJODRR) is a peer reviewed open access journal publishing research manuscripts, review articles, editorials, letters to the editor in Dermatological Research and Reviews (Indexing information).

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American Journal of Dermatological Research and Reviews

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