American Journal of Dermatological Research and Reviews


Histomorphometric Evaluation Of The Effect Of Semi-Solid Formulation Of Conocarpus Erectus Leaves On Fibroblasts And Inflammatory Cells In The Process Of Tissue Remodeling

Research Article of American Journal of Dermatological Research and Reviews Histomorphometric Evaluation Of The Effect Of Semi-Solid Formulation Of Conocarpus Erectus Leaves On Fibroblasts And Inflammatory Cells In The Process Of Tissue Remodeling Aline Fernandes da Silva *; Mateus Porfírio Rodrigues ; Arthur Francisco Silva Santana ; Tatiane Bezerra de Oliveira ; Jéssica Andréia Pereira Barbosa ; Marllon Alex Nascimento Santana Introduction: The wound can be defined as a skin lesion caused by chemical, physical or biological factors leading to cutaneous discontinuity. Based on the healing process, the evolution of the wounds can be mentioned as acute and chronic. Healing is the tissue repair process coordinated by biochemical and histological factors to restore tissue integrity. Since ancient times, medicinal plants have been used as a therapeutic resource, contributing to the treatment and prevention of various diseases. The species Conocarpus erectus Linnaeus, popularly known as “mangue de botão”, is found in the mangrove and stands out for presenting analgesic, anticancer, antimicrobial and hepatoprotective properties. Objective: Evaluate the ability of semi-solid formulations of C. erectus leaves through the histomorphometry of fibroblasts and inflammatory cells in the tissue remodeling process of cutaneous wounds in Wistar rats. Methodology: For the evaluation of the cicatrizant activity were obtained formulations containing 10% of the hydroalcoholic extract of the dry and fresh leaves of C. erectus (FHFCS and FHFCF 10%, respectively), manipulated within the standards and quality control for medicaments in the Laboratory of Pharmacotoxicological Prospecting of Bioactive Products of Universidade Federal de Pernambuco. To evaluate the healing activity, excisional cutaneous wounds were surgically made in the dorsal midline of the cervical region of Wistar rats (n = 5), these were standardized (6 mm²) and performed with animals previously anesthetized, after tricotomy and adequate antisepsis. Then, the wounds were treated with daily topical application (± 95 mg) ...

Face Powders: Formulation Considerations

Review Article of American Journal of Dermatological Research and Reviews Face Powders: Formulation Considerations Abdul Kader Mohiuddin Dr. M. Nasirullah Memorial Trust, Tejgaon, Dhaka The face powder was demanded by many nations in the world in the beginning AD and in Asia white skin was believed to be the sign of aristocratism, membership of the elite, and yet, white color is the pure symbol of the internal beauty and nobility. In addition, some face powders are sold in varying specialty shades to suit different skin needs; for example, a face powder with a greenish tinge will minimize the appearance of redness, while a purple-tinted powder may help the appearance of sallow or yellow skin. There is a legitimate reason to use face powder, and the pharmacopeias prescribe them in the treatment of many skin affections. At all events the proper use of powder is beneficial, it lightly covers and unifies a complexion, hiding the ravages of time, improving even the beautiful face. Face powder comes in different shades to match varying skin tones, and it is a good idea to choose the skin tone that most closely matches the natural skin. This will help the makeup appear more natural; it should be virtually unnoticeable. It may be necessary to use different face powders for summer and winter, as the skin may become tanner in the summer, or drier and in need of extra moisture in the winter. They are of benefit in acne, freckles, sunburn and red nose. Beneath their attractive aspect and odor, face powders should be made by the perfumer to combine the qualities of an elegant cosmetic and therapeutic agent; they must primarily possess adherence, lightness and be transparent; secondly, they should be detergent and delicately absorbent in order to aid the natural functions of the skin, ...

Urbanization, Environmental Pollution & Skin Aging

Review Article of American Journal of Dermatological Research and Reviews Urbanization, Environmental Pollution & Skin Aging AK Mohiuddin Department of Pharmacy, World University of Bangladesh 151/8, Green Road, Dhanmondi, Dhaka – 1205, Bangladesh The skin aging process, which is prompted by environmental variables, is named untimely or extrinsic skin aging process and can be recognized from the sequentially (intrinsic) skin aging process by trademark skin aging signs. Albeit human skin goes about as a biological shield against pro-oxidative chemicals and physical air pollutants, prolonged or tedious presentation to abnormal amounts of these pollutants may have profound negative impacts on the skin. Sexual orientation contrasts in toxicity have been accounted for some substances. Youngsters are known to be increasingly defenseless against the antagonistic health impacts of air pollution. Environmental pollution by traffic is additionally connected with the event of indications of extrinsic skin aging. Heavy metals, for example, cadmium, lead and mercury are regular air pollutants that posture health hazards because of bioaccumulation. Ozone in the stratosphere has protective impacts by sifting solar UVR; be that as it may, in the troposphere ozone has toxic implications for skin. Because of scarcity of logical proof, there are no settled rules as of now accessible for protecting the skin against air pollution. Beside lessening presentation, potential protection techniques should concentrate on fixing the skin barrier, renewing antioxidant save, and diminishing inflammation brought about via air pollutants. Keywords: skin aging; particulate matter; Reactive Oxygen Species; collagen disruption; aryl-hydrocarbon receptor; photoaging ...

An Extensive Review on Sunscreen and Suntan Preparations

Review Article of American Journal of Dermatological Research and Reviews An Extensive Review on Sunscreen and Suntan Preparations AK Mohiuddin, Assistant Professor Department of Pharmacy, World University of Bangladesh 151/8, Green Road, Dhanmondi, Dhaka – 1205, Bangladesh The sunscreen industry is achieving remarkable worldwide prominence by responding to the growing need for skin protection with fast-paced innovation. Increased consumer awareness of the harmful effects of sunlight has fueled the demand for improved photo protection. The need for broad-spectrum protection from both UVA and UVB rays has inspired scientists worldwide to research new cosmetic formulations and delivery systems. More effective sunscreen actives, emollients and novel cosmetic and functional ingredients have been regularly added to the formulator’s repertoire. Creativity in innovation has been hindered only by regulatory agencies and patent restrictions worldwide. Familiarity with the current restrictive regulations and patent law infringements has become integral to any research effort attempting to provide improved protection to individuals affected by the sun’s damaging effects. The increasing incidence of skin cancers and photo damaging effects caused by ultraviolet radiation has increased the use of sun screening agents, which have shown beneficial effects in reducing the symptoms and reoccurrence of these problems. Unlike the situation in Europe where sunscreen ingredients are considered under cosmetics guidelines, the FDA is required to define sunscreens as drugs since they are advertised to prevent sunburn and, more recently, the risk of skin cancer. In the USA, the FDA has been regulating this industry since August 25, 1978, with the publication of the Advance Notice of Proposed Rulemaking. Sunscreens are considered drugs and cosmetics and therefore must be governed by the FDA-OTC monograph. With the variety of sunscreen agents used in cosmetic and UV protection products, Australia, Canada, and the European Union (EU) have also developed regulatory protocols on safe sunscreen ...

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American Journal of Dermatological Research and Reviews (ISSN:2638-1893; DOI:10.28933/AJODRR) is a peer reviewed open access journal publishing research manuscripts, review articles, editorials, letters to the editor in Dermatological Research and Reviews (Indexing information).

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American Journal of Dermatological Research and Reviews

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