American Journal of Microbiology and Immunology


Review Article of American Journal of Microbiology and Immunology Review on Plants Therapeutic Effects against Gastrointestinal Microbes Abdallah, M.S 1&.,Rusea, G2., Mustafa, M.2 and Nallapan, M2. 1.Desert research monitoring and control centre, Yobe State University, Damaturu, Nigeria. 2.Department of Biology, Universiti Putra Malaysia, Serdang 43400, Selangor Malaysia. Plants play a vital role in many health care systems, be it rural or an urban community. Plants became familiar as medicine due to the ancient ideologies and believes. Several plants parts of plants served as medicines to so many ailments including gastrointestinal ailments, due to the fact that their active ingredients are powerful against the microbes. Most of the microbes identified were gram negative bacteria as well as some gram positive. Some of the principal antibacterial components of plants were recommended being polar compounds. While most of the acknowledged components with antimicrobial activity extracted from plants were aromatic or saturated organic compounds which were more soluble in polar solvents such as water and methanol. As such plants materials in one way or the other are very active when dealing with microbes due to their active ingredients. Keywords: Ailments, compounds, Gastrointestinal, microbes and plants ...


Research Article of American Journal of Microbiology and Immunology Oedematous skin disease (OSD) transmission among buffaloes Arafa M.I. 1; Hamouda S.M. 1; Rateb H.Z. 2 ; Abdel-Hafeez.M.M*1.; and Aamer.A.A. 2 1Animal Health Research Institute, Egypt, Assiut Lab. 2Dep. of Ani. Med. Faculty of Vet. Med. Ass. Univ. During buffaloe OSD spread in a village affiliating to Assiut Governorate-Egypt, 44 buffaloe cows hosted and owned sporadically were subjected to the study. From 43 buffaloe cows (had closed lesions either edematous or nodular) and a buffaloe cow (had open ulcerative lesion), Corynebacterium pseudotuberculosis equi (C. ps. equi) as 72% and Corynebacterium pseudotuberculosis ovis (C. ps. ovis) as 28% were isolated and identified. Blood sucking insects hosted on the infected buffaloe cows (22) louse fly (Hippobosca equine) and 20 Haematopinus eurysternus lice were included during the study where both C. ps. equi and C. ps. ovis were isolated from Hippobosca equina ( H equina) but failed to isolate any biovar of C. ps. from Haematopinus eurysternus lice (H. eur.). Moreover, C. ps. equi was isolated from two H equina pupae – lab deposited – as well as a H equina second generation fly concluding that there is endosymbiosis nature of C. ps. limited only to H. equina fly which can transmit vertically. Keywords: Buffaloes, oedematous skin disease, Corynebacterium pseudotuberculosis, Hippobosca equina ...


Review Article of American Journal of Microbiology and Immunology Epidemiological Profile Of Patients With Rheumatic Mitral Valvopathy Limacedo Firmino da Silva1 Isabel Cristina Pinheiro da Fonseca1 David Emanuel Vilar de Oliveira Gomes2 Bárbara Talita Tenório da Silva2 Ana Cecília Souza de Amorim3 Cristie Aline Santos de Araujo3 Background: Rheumatic fever (RF) is a systemic, autoimmune and inflammatory, non-suppurative disease in genetically predisposed individuals with cardiac repercussions between 25-45 years old. It is estimated that 500,000 cases are 21,000 cases diagnosed in Latin America, accounting for 70% of cases of valvular disease in Brazil, predominantly in the northeast and southeast regions of the country. Commonly associated with underdeveloped regions and urban agglomerations, the predominance of this condition will be due to sociodemographic conditions, due to this, variables such as: level of schooling, sanitary conditions, primary health care and nutritional status of the susceptible are relevant to justify the predominance in these areas. Objectives: To outline the epidemiological profile of patients with mitral valvular disease with rheumatic etiology. Methodology: This is a descriptive-exploratory integrative review. The searches were carried out through electronic database PUBMED / MEDLINE and the Virtual Health Library (VHL) from August to September 2018. Of the 62 articles found, only 14 articles were selected because they were able to answer the guiding question: what sociodemographic characteristics are determinant for Streptococcus pyogenes infection? Results: The prevalence of pyogenes streptococcal infection in underdeveloped countries is due to poor sanitary conditions and poor access to primary health care that poorer areas face in the face of social inequality, which is indicated by the level of illiteracy, unemployment and lack of which contribute to the susceptibility to group A streptococcal infection. Conclusion: Social inequality is the determining factor for the prevalence of rheumatic fever in underdeveloped countries, further studies are required that encompass ...

The effect of Transfer Factor as Immunotherapy comparing with the effect of BCG in Mice challenged with Mycobacterium tuberculosis

Research Article of American Journal of Microbiology and Immunology The effect of Transfer Factor as Immunotherapy comparing with the effect of BCG in Mice challenged with Mycobacterium tuberculosis Jamal Bayed Salim.1,Ahmed K. Bolad2, Hamid Suliman A..2 andss Mujeeb A.Kabbashi3 1- Department of Medical Microbiology, Faculty of Medicine and health Sciences, University of Kassala, Kassala, Sudan 2- Al- Neelain University, Faculty of Medicine 2- University of Khartoum, Faculty of Medicine 3-Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, University of Sciences &Technology, Khartoum, Sudan Background: Transfer Factor (TF) is an immune modulator which stimulates the cellular arm of the immune system (killer lymphocytes), activates immune cytokine synthesis and regulates immune function (Lawrence, 1955).TF is very effective in those diseases in which CMI plays a relevant role in protection and control of the disease, such as intracellular bacterial diseases (tuberculosis). ( Estrada Parra, et al1955). TF are low molecular weight products from immune cells that are able to transmit the ability to express delayed-type hypersensitivity (DTH) and cell mediated immunity (CMI) from sensitized donors to non immune recipients (Kirkpatrick, 2000). Objectives: The aim of this experimental study is to determine the protective efficacy of transfer factor (TF)  as immunotherapy for mice in comparison to BCG. Materials and methods: A total number of 102 mice were examined  for their immunopotency and protective efficacy of Transfer factor (TF)  comparing to the protective efficacy  of BCG single and second repeated dose against challenge dose of M. tuberculosis (107 CFU) . A number of 20 mice were immunize with the attenuated strain of M. bovis, Bacillus Calmette-Guérin (BCG). After 21 days of BCG spleens of 10 tuberculous mice were removed aseptically for the preparation of TF. To evaluate the effect of TF 3 groups of inbred BALB/c male mice were injected with TF and challenged with virulent M ...

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American Journal of Microbiology and Immunology