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Introduction: Removal of the 3rd lower molars is nowadays a routine procedure in dentistry, but it is an action that can be damaged in the inferior alveolar (NAI) and lingual nerves, which are in association with the roots of the 3rd molars. Objective: To analyze causes, predisposing factors, symptomatology and treatment of NAI and Lingual paresthesia. Methodology: An integrative review was performed on the MEDLINE, LILACS and SCIELO databases, using the descriptors: Exodontia, Molares, Paresthesia. The inclusion criteria were: articles in Portuguese or English and published between 2013 and 2017. Result and Discussion: There were 637 articles related to the topic, 32 selected and 5 used as theoretical reference. Paresthesia is characterized by sensory loss of the affected nerve, resulting from iatrogenic injury or bacterial infections. The predisposing factors for this lesion range from the patient’s age, tooth root development, operator ability and teeth impaction. Weeks after surgery, the patient may report symptomatology related to NAI paresthesia as loss of lip sensitivity and on the affected side, altered sensitivity to cold, heat, pain, numbness, tingling and “pinching”. There may also be symptoms related to Lingual Nerve paresthesia as a burning sensation in the tongue, changes in taste and constant nibbling on the tongue. The treatment results from the regeneration of the injured nerve fibers. It usually does not require any iatrogenic intervention. However, it is used drugs (Cortisone and Vitamin B1), low intensity laser and microsurgeries for axonal regeneration. Conclusion: The frequency of 3rd molar extraction leads to a higher number of postoperative complications. Therefore, paraesthesia arises from lack of surgical planning, technical inability and incorrect instrumentation. Thus, detailed evaluations of complementary imaging (panoramic radiography and computed tomography) are of paramount importance, as well as prophylactic measures such as correct diagnosis, anatomical and technical knowledge of the professional, and adequate…

Introduction: When treating a diabetic patient, it is important to consider a number of factors, such as the patient’s blood glucose behavior and rate. Objectives: To approach as situations and behaviors of the dental surgeon towards the diabetic and to explain actions that will lead to success without patient care. Methodology: A bibliographic review was done in the virtual libraries SCIELO and PubMed, use the articles: “Diabetes and Dentistry” and “Conduct of diabetics in dentistry”. It was used as inclusion criteria for published articles from 2013 to 2017, in the Portuguese and English languages, which relate diabetes to dentistry and conduct of the dental surgeon. Results and Discussion: The survey resulted in 3,011 articles, 18 of which were separated by presenting a greater relation with the subject, but only five attendants to the inclusion criteria. The most common clinical sign in diabetic patients is hypoglycaemia, causing pallor, cold sweat, drowsiness, headache and others. In case of unconsciousness or dental surgeon, administer ampoule with 10 ml of 25% glucose solution intravenously. Hyperglycemic patients show signs and symptoms characteristic of metabolic ketoacidosis, such as the presence of a hetero-oesthetic should be referred to the doctor. The dentist should suspect undiagnosed cases, ask about polyphagia, polydipsia, polyuria, and weight loss. If so, refer to laboratory tests and doctor. Controlled diabetics may be treated in a similar manner to the non-diabetic patient. Prioritize short appointments early in the morning after a meal. Normal diet is advised in the diet. An antibiotic prophylaxis for certain passages can be made. Oppose the blocking anesthesia, avoiding solutions with vasoconstrictor based on adrenaline, because we promote the breakdown of glycogen into glucose, causing hyperglycemia. Conclusion: The dental surgeon must know the systemic associations of diabetics in order to serve them more safely in all clinical procedures.

This paper examined the nature of trade relations between the Benin Kingdom and the Dutch between 1593 and 1741. It documented and analysed the features of Benin-Dutch trade; the major items of trade and means of exchange; as well as the terms of the Dutch-Benin Trade Treaty of 1715. The paper further interrogated the causes of the breakdown of trade relations between the two countries in 1741. Data for the study was obtained extensively through archival materials as primary sources; and books, newspapers, articles, theses, dissertations and journals as secondary sources. The paper found out that trade was the hallmark of Benin-Europeans’ relations between the 1440s and 1741. It observed that the trade contact between Benin and the Dutch started around 1593 and declined around 1741. It concluded that the trade relations brought mutual benefits to both parties: great prosperity and fame to the Benin kingdom; and economic buoyancy to the Dutch.

Introduction:Acute kidney injury (AKI) may predispose the onset of chronic kidney disease (CKD) and hypertension through changes in renal NADPH oxidase and renal fibrosis. Objectives: To investigate, in rats, whether AKI induces later renal fibrosis through NADPH oxidase activation. Methodology: This protocol was approved by the Committee of Ethics in Animal Experimentation of UFPE (nº 23076.060473/2014-91). Male Wistar rats (120 days-old; n=8) were submitted to AKI through bilateral renal ischemia-reperfusion injury (IR; 45 min ischemia followed by 30 days of reperfusion). One group (n=8) was submitted to IR in the presence of oral apocynin administration (100 mg/kg) 24 hours before and after IR, to inhibit NADPH oxidase activity, while other (n=8), received daily oral treatment with apocynin (100 mg/kg) 24 hours after reperfusion until the end of experiment. These groups were compared to a control group submitted to simulation of IR procedure. Thirty days after reperfusion, it was evaluated creatinine clearance (ClCreat) and systolic blood pressure (SBP), as well as kidney collection, to evaluate lipid peroxidation, NADPH oxidase activity and collagen deposition. Statistical analysis was performed using one-way ANOVA followed by Newman-Keuls test (P

Introduction:The Extended Alternative Communication ¬ (EAC) brings together other forms of communication, as well as oral language, such as use of gestures, sign language, facial expressions, use of alphabet boards or pictographic symbols, to the use of more sophisticated systems such as recorded or synthesized voice communicators and computers. The causes that make communication of elderly patients impossible through speech are the most diverse. This difficulty in oral language expression can compromise the relationship between the patient and the staff such as the patient and its family, resulting in frustrated, nervous, anxious, agitated and depressed patients. Objetives: Report the Alternative Extended Communication method and their contributions to the process of internalization of elderly patients unable to communicate through speech. Methodology: For this study, the database Pub Med was consulted such as selected review articles from the entrance of the terms: extended alternative communication, speech therapy, critical elderly patients. Results and Discussion: It was found that, patients admitted to the ICU experience a big potential traumatic experience and many develop serious emotional problems. These experiences come with a psychological suffering and which has a harmful effect on the overall rehabilitation of the patient. EAC is a clinical and educational practice where the speech therapist tries to compensate and to facilitate for losses and disabilities of the individuals with severe disturbances of expressive communication and / or comprehension disorders. It provides a significant gain for the team and the family with the understanding of what happens in terms of communication and consequently the reduction of anxiety and s¬tress, avoiding frustrating situations for the patient. Conclusion: The theoretical aspects presented in this work, lead us to conclude that it is of utmost importance to the implementation of a larger communication system and alternative critical elderly patients hospitalized, noting that long-term treatment would be…

Introduction: Research on the relationship between spirituality and health seeks to understand how religious beliefs and behaviors relate to or interfere with health. Spirituality as a coping strategy promotes meaning and ordering of life and suffering. Religious activity is an effective element, both to help maintain healthy stress and to improve the quality of life. The exercise of faith and the practice of religiosity are strategies, often used by mothers of hospitalized babies, as a way of dealing with a long period of hospitalization and feelings of guilt, anger, anxiety, fear, sadness and impotence. Objectives: Looking for new ways of thinking about the practice of caring for humanization, in a more integrated vision of the human being, group activities were carried out aiming at the expression and elaboration of feelings with the objective of stimulating faith and spirituality as a strategy of enfretamento in the hospital context. Methodology: Weekly conversation with mothers, caregivers and relatives of infants admitted to the Neonatal ICU and the Kangaroo Intermediate Care Unit were conducted. We used dynamics, musicality, reading of texts for reflection and prayer. Results: From January 2015 to October 2017, 125 wheels took place, in which topics such as peace, friendship, trust, joy, gratitude, fear, hope, forgiveness and perseverance were addressed. The talk wheels were attended by several professionals, including psychologists, physiotherapists, speech therapists, occupational therapists, nursing staff and hygienists. On average, five professionals and 15 mothers and / or accompanying persons participated per wheel. Conclusion: It was noticed that this activity promoted the strengthening of the participants’ faith, improved interpersonal relationships between the mothers and the mothers with the team, as well as facilitated the resolution of conflicts and promoted the capacity for empathy and mutual help.

Introduction:At the present time, a pathological profile is identified in the work environment, characterized by the prevalence of health problems marked by chronic diseases, which are added to mental and physical stress-related impairments. In the hospital context, the Intensive Care Unit is perceived by the team that acts as one of the most aggressive, tense and traumatizing environments. In the Maternity School Januário Cicco (MSJC), the Neonatal Intensive Care Unit (NICU) is the sector with the highest sickness absenteeism due to illness, which results in the reduction of the team and, consequently, overloading of tasks. Nursing technicians are exposed to the intensive emergency, to the sound of the sterilizers, besides the demands and collections of the patients, relatives and doctors. The physical and mental exhaustion that affects these workers demanded of the institution strategies that could promote health and quality of life at work. Objectives: The activities aim to improve the level of motivation of nursing technicians, promote the integration of the multiprofessional team, provide a space for listening and acceptance of feelings, improve the communication channels of the sector and the organizational climate, reduce absenteeism, as well as contribute quality of life at work. Methodology: Since June of this year, group activities have been held monthly for 2 hours, conducted by the multiprofessional team of the MSJC (psychologist, social worker, occupational therapist, nurses, pediatrician and physical education professional) using musicalization, work gymnastics, dynamics, relaxation techniques, acupuncture and dramatization. Results: At each meeting, an average of 30 nursing technicians participated. There was an improvement in motivation and organizational climate, reduction of sick leave, greater interaction among the team, as well as improvement of communication channels in the sector. Conclusion: The activities developed have made it possible to improve the quality of life in the work of NICU nursing technicians.

Introduction:Although the main task of the voice is communication, in modern society a third of the population depends on the voice as a primary instrument in their work. Among these professionals, the teacher can be highlighted as the voice professional with the highest occurrence of dysphonia. Objective: This article aims to analyze the perception of teachers about the vocal health workshop in a private school in the city of João Pessoa. Methodology: An exploratory research was conducted, with a sample of 7 teachers. A questionnaire was used as instrument, and a descriptive analysis was performed through SPSS software. The project was approved by the Ethics Committee of UNIPE with the approval number 1.829.531. Results and Discussion: The sample was 100% composed of women, ranging in age from 27 to over 50, with up to 20 years teaching. Among the participants, 57.1% said they had already lost their voice during work. Conclusion: It was concluded that through the vocal health workshop they were able to know the importance of care with the voice, but not all of them changed their habits towards the necessary care. It was also noticed that all of the participants presented symptoms for prolonged use of the voice, although they do not keep the exercises as part of their daily life. This signals for the importance of actions towards health promotion and prevention of these professionals.

Introduction: The selection of reference genes (RGs) is considered as one of the most critical steps for RT-qPCR since these genes must show stable expression under varying experimental conditions, cell types, and developmental stages, among other factors. Despite the fact that there are publications for this topic in the grapevine, the majority of them are based on cultivars infected by fungi or subject to abiotic stress. To our knowledge, there is no study investigating the selection of RGs in vine affected by X. campestris. Objective: To select for suitable RGs for gene expression normalization of RNA-Seq expression data from two V. vinifera cultivars with contrasting phenotypes for resistance to this pathogen. Methodology: A search in the literature for publications that selected explicitly for RGs in grapevine was performed, further including those articles using conditions of biotic (preferentially) or abiotic stress. After an initial prospection, the retrieved primers sequences were evaluated by an in silico PCR assay using the Primer-BLAST software at NCBI aiming to align the sequences in the V. vinifera genome and its specific amplification, thus confirming, therefore, gene annotation. Finally, the RGs were tested by both conventional PCR and RT-qPCR and using a negative control (NTC) reaction each tested primer pair. Results and Discussion: From 14 RGs selected, nine (CYP, VATP16, EF1α, TRU5, TCPB, TIF-GTP, GAPDH, ACT, and 60SRP) met the criteria all the criteria described above and its sequences were sent for primer synthesis. The detection by both conventional PCR and RT-qPCR confirmed the amplification of all tested RGs. However, under the RT-qPCR, it was possible to not unspecific amplification on NTC of two RGs (CYP and VATP16), therefore confirming the resolution of the assay. Conclusion: A selection of putative candidate RGs was carried out by showing satisfactory results on initial tests on both convencional PCR and…

Introduction: NPM1 gene mutations are the most frequent mutations in adults with acute myeloid leukemia (AML) they are found in 30% of adult de novo AML and in 60% of AML with normal karyotype. Because its clinical relevancy the European Leukemianet group recommends the research of NPM1 mutations at diagnosis to better stratify the risk of patients with AML. The current methodologies used to detect these mutations – Sanger sequence and fragment analysis- are expensive, therefore, there is the necessity of the development of new and cheapest methodologies for implementation in a routine diagnosis for patients with AML, mainly thinking of development countries. Objectives: To validate the technique of PCR followed by electrophoresis on agarose gel to detect mutations in NPM1 gene in patients with AML. Methodology: 196 patients with de novo AML were analyzed. Conventional PCR was made and the products of its amplification were seen by electrophoresis on agarose gel with 4%. The gold standard used for comparisons was the fragment analysis by the MEGABACE 1000 equipment (GE Healthcare- Amersham). Results and Discussion: 19,4% of the patients were mutated (38 of 196 patients) and 80,6% were normal (158 of 196 patients). All mutations were insertions of 4 base pair. The conventional PCR technique revealed a sensibility and specificity of 100% showing to be a sensitive, simple and economic method which can be used as an alternative to others more expansive methodologies that also need a more specialized professional to the diagnostic routine of patients with AML. Conclusions: This study proposes a faster, economic and sensitive technique to detect mutations on NPM1 gene in a routine diagnostic of patients with AML.