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    Objective: To review articles and case reports on Prader-Willi Syndrome, observing its characteristics and relating its treatment to the various fields of health. Methodology: As a result of articles found in the following databases: PubMed, MedLine, SciELO and European journal of human genetic Results: SPW can be diagnosed in the neonatal period through genetic studies or physical characteristics, it is a disease that has no cure, but can be treated, preferably early, to ensure the greatest comfort to the patient during his life. Conclusion: Because it is a syndrome that affects the patient in behavioral, structural and intellectual environments, act jointly to ensure the well being of the individual with SPW.

  • Design of NSGA-III Tuned FPC for AMSS

    Airborne missile servo system (AMSS) is a complex time-varying nonlinear system and the design of which is a multi-objective optimization problem. Fuzzy PID controller (FPC) is demonstrated appropriate for complex time-varying nonlinear systems but the design of which needs a tedious trial and error process. Non-dominated Sorting Genetic Algorithm III (NSGA-III) is a multi-objective evolutionary algorithm with good generality and robustness which can do a big favor for parameter tuning of complex system. This paper develops NSGA-III for parameter tuning in design process of FPC. Resulting FPCs are tested with model of AMSS on simulink. For further comparison, performance of conventional PID controller and sectional PID controller which is widely used in the engineering are also shown. Comparison shows that NSGA-III tuned FPCs have the better performance in AMSS.


    Diabetes Mellitus it is a condition that can result from defects secretion and/or insulin action involving specific pathogenic processes. To analyze the profile of registered diabetic patients in the program “Here’s People’s Pharmacy” of a commercial drug store in the municipality of Paraná-RN, checking the type of diabetes mellitus that is more present, the most commonly used drugs and what other diseases are reported. Study applied, descriptive and quantitative and qualitative, with a questionnaire to registered diabetic patients in the program “Here’s People’s Pharmacy” in a drug store located in the city of Paraná-RN. The study sample was 50 people. Of the participants, 96 % had diabetes mellitus type 2. The use of medicines, metformin was the most used (52 %), followed by glibenclamide (46 %) and insulin (2 %). With regard to the presence of other diseases hypertension and high cholesterol prevailed about 20 % and 8 %, respectively. It is important the involvement of health professionals in the treatment of diabetes and other chronic diseases, however, it is essential that the patient is aware that the greater re-sponsibility and commitment are in himself, and ultimately with your family or caregiver.


    Introduction: Diabetes mellitus is considered a metabolic syndrome of multifactorial origin characterized by hyperglycemia and disorders in the metabolism of carbohydrates, proteins and fats that occurs when there is no insulin or when insulin does not perform its function properly. Diabetic foot injury is one of the most frequent implications of diabetes mellitus. It is associated with many factors, such as peripheral vascular disease and peripheral neuropathy, which in many cases may compromise the entire limb. In this context, the systematization of nursing care starts as a systematic method that makes it possible to identify and understand the needs of the patient. The application of the Systematization of Nursing Assistance brings benefits to the client, the institution, professionals and to nursing as a whole. Objectives: To verify the inference of the nursing diagnosis “Impaired skin integrity” and the use of the other steps of Nursing Care Systematization in the treatment of diabetic foot wound. Methods: This is an exploratory clinical study of the case-study type, carried out during the period of clinical nursing internship in a public hospital in the city of Recife-PE, from September 17 to October 11, 2018 Results: A 77-year-old male patient with diabetes mellitus, with MIE lesion and hallux amputation, fourth and fifth finger. During the aforementioned period, the data was collected through anamnesis, physical examination, records in the medical record and analysis of laboratory tests. In this way, it was possible to plan the Nursing Care Systematization and to apply the interventions for the diagnosis “Impaired skin integrity”, being: daily skin examination with image records and monitoring of wound healing, daily dressing with use of serum saline at 0.9%, Essential Fatty Acids (AGE) and Hydrogel in the necessary places, orientation on how to change the decubitus periodically and use of cushions in the regions, aiming…


    Introduction: The World Health Organization (2004)4, considers the alcoholic as an excessive drinker whose dependence on alcohol is accompanied by mental disorders, physical health, relationship with others and social and economic behavior.Objective: To identify the sociodemographic profile and the lifestyle of users of the Unified Health System (SUS) with diagnosis of alcoholism in the city of Vitória de Santo Antão, PE. Methodology: Cross-sectional, descriptive and quantitative study, performed in a Hospital Unit agreed with SUS, located in the city of Vitoria de Santo Antão, PE. Data were collected with patients admitted from September to November 2016, through of the questionnaires on the sociodemographic and lifestyle conditions of alcoholics. The data were statistically described. The research was approved by the Research Ethics Committee involving Human Beings of the Health Sciences Center – Federal University of Pernambuco (CAAE: 55297416.0.0000.5208). Results: Twenty-eight male patients aged 19-65 years old, were evaluated. It was observed that 93 % did not finish high school, 57 % with income of up to one minimum wage, 74 % unemployed and 70 % smokers. Conclusion: The present study verified a low socio-demographic condition and an unsatisfactory lifestyle in the population previously evaluated.

  • The Epidemiology of The Zika Virus And Microcephaly

    The development of strategies to manage the Zika virus epidemic constitutes a challenge for the scientific community. Develop tele-education actions in the field of human communication health with an emphasis on implications stemming from the Zika virus and microcephaly for professionals of the Family Health Strategy and students at the Federal University of Pernambuco. The experience of a set of three web conference seminars is described. The lectures addressed the epidemiology of the Zika virus and microcephaly, speech/hearing therapy, breastfeeding and feeding children with microcephaly. The mean number of connected points was 1.6 per session, with representatives of metropolitan Recife and the municipality of Lajedo. A total of 13 individuals participated in the action (three students and 10 healthcare professionals). All considered the topics interesting and relevant to the profession and all reported being satisfied with the experience. Web conference seminars can contribute to the creation of a dialog among different actors linked to health promotion actions with the aim of potentiating integral care, especially in response to current and future epidemics.


    Introduction: The brain is a seriously complex organ that controls and modulates bodily functions. However, it can be affected by vascular alterations, such as a stroke, which is characterized by the total or partial decrease of blood flow in a certain region of the brain, constituting one of the major causes of morbidity and mortality worldwide. The present study brings to the systematization of nursing care to a patient with sequelae of stroke. Objective: To describe the nursing interventions performed to a patient with a stroke sequelae during the period of the Nursing course at the Federal University of Pernambuco. Methods: An exploratory study of the case report, developed based on the steps of the nursing process, considering the results of laboratory tests and chart analysis, during the period of hospitalization in a public hospital in the city of Vitória de Santo Antão, in the period of May 2018. Results: In view of the clinical findings and after the history and elaboration of the nursing diagnoses were found, a nursing care plan was carried out with subsequent nursing interventions such as: checking of vital signs, cephalocaudal physical examination, daily dressing on pressure lesions, guidelines to the companion as to the importance of moving the decubitus, preserving the raised limbs on the bed, keeping the patient’s skin always hydrated, performing limb movements, intolerance of the patient. It was possible to perceive an improvement of the general picture of the client in question, after the nursing interventions were put into practice. Conclusion: It is concluded that nursing interventions, in the promotion of self-care and rehabilitation capacity, corroborate in the reduction of damages and disabilities, promoting a better quality of life for the patient with stroke sequelae and awareness of family members in the importance such care.

  • Issues Behind Choosing Alternative Measures to Cancer Care & Cure

    Regardless of extraordinary development, regular therapy misses the mark in cancer the board. There are two noteworthy obstacles in anticancer drug development: dose-limiting poisonous symptoms that diminish either drug viability or the QoL of patients and convoluted drug development forms that are exorbitant and tedious. Cancer patients are progressively searching out alternative medicine and may be hesitant to uncover its utilization to their oncology treatment doctors. Be that as it may, there is constrained accessible data on examples of use and viability of alternative medicine for patients with cancer. The cost of delivering cancer treatment is estimated to rise globally with a projected total spending of $458 billion by 2030 [1]. However, the financial burden stems from employment loss, cost of care even when patients don’t require chemotherapy, out of pocket costs’ opportunity costs of informal care time and can continue long after the death of the patient. As adjuvant therapy, numerous conventional medicines demonstrated adequacy against mind, head and neck, skin, bosom, liver, pancreas, kidney, bladder, prostate, colon and blood cancers. Chemotherapy and radiotherapy are still generally customary methodologies for treatment of patients harboring propelled cancer. Customary chemotherapy likewise connected with neuropathic pain, fatigue and sleep aggravation, anxiety and depression, mouth sores, nausea and vomiting, early satiety, alopecia, bone and muscle squandering. Worldwide, some 60%-80% people depend on alternative medicines, which is also true for nearly 40% to 70% European, 50% Italian, 40% Korean, 30% British and up to 87% of Australian cancer patients [2]. Use of unapproved/unlabeled/wrong herbal treatment is not uncommon and also drug interactions reported phyto-therapeutics in oncology. Futile medicine use reported in one-fifth of terminally ill cancer patients (statins and antidementia drugs in nearly 100% cases, antihypertensives and bisphosphonates in nearly 30% cases) [3,4]. So, Proper and up-to-date knowledge is necessary in using alternative treatment…

  • Analysis on the Growth Path of Silk Road Story and Creative Industry

    Exploring the growth path of Silk Road story and creative industry focuses on three dimensions: industrial thought, business model and product modality. The ideological construction path of Silk Road story and creative industry includes interpreting the culture of creative industry, positioning the goals of creative industry and reflecting the values of creative industry. The business model innovation path of Silk Road story and creative indu0stry focuses on the business model innovation the value appreciation of the whole industrial chain. The growth path of Silk Road story creative products should first focus on the classification and creation of creative products, then determine the development and design path of products.


    Purposes:To evaluate the efficiency of DAA (Direct Antiviral Agent), in particular sofosbuvir, ledipasvir in Hepatitis C treatment for patients with kidney transplants. Take note in the side effects and drug interactions during the treatment processes. Method:Intervention, prospective, cohort, case studies, non-randomized, open on to all kidney transplant cases with chronic Hepatitis C tested positive HCV RNA (+); the patients from the cases above had agreed to be the research’s subjects from 11/2015 to 8/2018 at Cho Ray hospital. Two regimens Sofosbuvir/Ribavirin and Sofosbuvir/Ledipasvir have been used for treatments, which depend on HCV genotype and liver cirrhosis levels. Results:In 440 patients who had been observed after kidney transplants, 44 cases anti HCV (+), 29 cases HCV RNA(+) and 4 cases HBV/HCV Confection. There were 15 cases with chronic Hepatitis C participated in study. Males made up 66.6% of the group with the average age 49± 7.06 yrs. There were 6.7% of them not taking full-course treatments. 80% of the patients were infected with only C virus, while 20% of the patients were co-infected with B and C virus. 40% of them had histories of previous blood transfusions. The ratio of patients with elevated liver enzymes was 33.3%. Genotype 1 (a and b) was 33.3%, genotype 2 was 6.7%, genotype 6 was 53.3% and 6.7% unidentifiable genotype. There were 2 cases which were treated with Sofosbuvir/Ribavirin regimen and 13 cases which were treated with Sofosbuvir/Ledipasvir regimen. Rapid virologic response (RVR) is 100%. Sustained virologic response (SVR) within 12 weeks and 24 weeks is 100%. Relapse ratio 0%. In regimen using Sofosbuvir / Ledipasvir, the side effects are mild and transient, including skin irritation, digestive disorders which account for 7.7%. In regimen using Sofosbuvir / Ribavirin, side effects including severe anemia, fatigue, loss of appetite related to Ribavirin occur in 50% of cases…