Introduction. Kabuki syndrome is a rare congenital anomaly characterized by defects craniofacial, intellectual and cardiac. It has a clinical diagnosis and its main phenotypic characteristic observed is the facial dysmorphia, very similar to the makeup used by the Japanese theater actors Kabuki. This review aims to describe the characteristics of Kabuki Syndrome and its main implications. Methodology. A literature review was conducted with research on the following databases: PubMED, BVS and SCIELO. Five scientific papers and two dissertations were selected. Results. It is believed that the disease is related to a mutation of the MLL2 gene, which is responsible for coding the group of Tritorax proteins, which have as their main regular function and genetic expression. Conclusion. This disease is still poorly understood in the health not having a clarity about their phenotypic / genotypic relationship needing further studies on the subject.
Objective: To apply a health education action on the empty nest syndrome (SNV), verify its applicability in the quilombola community, as well as its peculiarities. Methodology: Conversation wheels were held in a quilombola community in the state of Alagoas, with a simplified approach taking into account the community’s lack and social inequality, using theatrical presentations, with the purpose of informing about the pathology, considering its signs and manifestations. Results: This action demonstrated in a population that is located in a quilombola community, distant from the city, making education, health and assistance very limited, so that it can lead to health education, it was very rewarding, where it was possible to pass the scientific knowledge and be able to enrich us with the knowledge of this community. Conclusion: It was notorious that the community understood and was told to identify themselves with the information about SNV. Considering the observations after the activities were carried out, the importance of health education in this community became evident, since, because it is a community far from society, with the media very limited, they are not aware of the news outside the community. It is evident that the Empty Nest Syndrome is a psychic and social problem. It is then the emergence of new strategies of care that can provide psychic and social support to this community, making it possible to avoid the loss of functionality and social isolation, factors prone to triggering suffering.
Introduction: Aase-Smith syndrome is a rare genetic disease characterized by anemia and skeletal deformities. The age at the start of symptoms is since birth and it´s commom in both sexes. * Show the syndrome problem in individuals, their clinical and behavioral characteristics. Contribute to a better understanding of the Aase Syndrome with syndromes that lead to similar symptoms. Methodology: This literature review on the syndrome was performed with research of information in published scientific articles. Result: Analyzed some common and rare symptoms, reports of observed cases of Aase-Smith syndrome, jointly with their respective symptoms and other syndromes, in addition whit the authors’ arguments in their articles that interpose, for example, about the genetic inheritance of the syndrome is dominant or recessive. Conclusion: The relationship between Aase syndrome and congenital hypoplasia anemia is not fully understood by the scientists and the syndrome represents a challenge in the approach to treatment, since this syndrome has no cure and does not present a standard treatment approach.
Introduction: The discovery of HIV compromises individuals in various areas of their lives, which can compromise their quality of life. Objectives: To investigate the topics covered in online journals about the factors that influence the quality of life of people living with HIV / AIDS. Methodology: Integrative Revision carried out in October 2018 in the Regional Portal of the Virtual Library (VHL), applying as descriptors “HIV”, “Acquired Immunodeficiency Syndrome”, “Quality of life” and using as a cutback the last 5 years, with a certain question The study sample consisted of 10 original articles, divided into three thematic categories: “alterations” and “quality of life” related to HIV / AIDS. bodily, clinical, emotional, “” social support, “” orientation about disease. Results: The study sample consisted of 10 original articles, divided into three thematic categories: “body, clinical, emotional,” “social support,” “orientation about the disease. Conclusion: The quality of life of individuals with HIV / AIDS reflects significantly in the maintenance of their well-being, which highlights the importance of attending to factors that may modify this situation and be able to go beyond the pathology.
Introduction: Dengue is the world’s most important arboviral disease in terms of number of people affected ans is transmitted by mosquitoes Aedes Aegypti. The main strategy for epidemic prevention and control is population behavior in the prevention and insecticide fumigation. Objective: The following study aims to describe the contributions of the population about prevention practice of dengue. Materials and Methods: This is a descriptive research. Studies of any design published from 2012 to 2016 available in english, portuguese and spanish were included. The survey was conducted in the Scientific Electronic Library Online (SciELO). Results and Discussion: Six articles were found that match the eligible criterias. In accord to them, it was realized that the Brazilian population has a slouch behavior in practice prevention of mosquito outbreaks, providing opportunities that the mosquito prolife, and not getting success in disease control. This may occur because of poor infrastructure conditions in most cities, as well as the lack of preventive actions both private and public initiative. Conclusion: It was clear that the Brazilian population needs to engage in preventive actions related to dengue, but also charge more effective action of public policies to assist them in combating the proliferation of the mosquito.
The yellow fever is treated of a disease infectious endemic sharp viral of origins in Africa and in areas in South America. According to OMS (World Organization of the Health), they are dear annually 200.000 cases of the disease. The etiological agent of the yellow fever belongs to the family Flaviridae and to the gender Flavirirus, which is the responsible for other diseases in the man. The treatment of the yellow fever is constituted with uses of painkillers and antitérmicos with attention specifies of acid acetilsalicílico and flowed in the pictures hemorrágicos. This work intended to accomplish a bibliographical revision on the yellow fever. Now there are several indicative factors of reurbanização of the disease, the incidence of the virus happens in endemic areas, infecting the man and his/her natural host
Study the Role of Combined M2-Pyruvate kinase, Calprotectin and Occult Blood Test as Fecal Biomarkers for Early Detection of Colorectal Cancer
Background and study aim: One of the main requirements of biomarkers for detecting CRC is that it must allow detection of the disease at earlier stages. The current study is designed to investigate the role of combined M2-Pyruvate kinase, Calprotectin, and Fecal occult blood test measurements as fecal diagnostic biomarkers for early detection of colorectal cancer. Patients & Methods: Total number of 72 subjects (48 patients and 24 healthy controls) were included in the study. Patients with cancer colon and patients with organic non-malignant colorectal lesions were recruited from Oncology and Gastroenterology Outpatient Clinics and Inpatient Department Menoufia University Hospital. Results: There was a highly significant difference between studied groups regarding age and gender (P> 0.001), cancer colon was higher among old age (mean ± SD is 58.96±6.3) and males (70.8%), There was a highly significant difference between studied groups regarding Hb, CRP and ESR (P >0.001); lowest Hb level was detected in cancer group (8.7±1.7). On the other hands highest CRP and ESR levels were in cancer group (7.29±4.47) and (14.71±6.19) respectively. There was a significant difference between studied groups regarding platelets (P >0.05); lowest platelet number was detected in cancer group (272.4±66.9). There was non-significant difference between studied groups regarding WBCs (P 0.001), There was a highly significant difference between studied groups regarding M2-Pyruvate kinase and Occult Blood (P >0.001), There was highly significant difference between M2-PK in cancer and control groups (p >0.001), There was significant difference between calprotectin in cancer and control groups (p >0.05), There was highly significant difference between occult blood in cancer and control groups (p >0.001), There was highly significant difference between Combined M2-PK and Calprotectin in cancer and control groups (p >0.001), There was highly significant difference between Combined M2-PK and Occult blood in cancer and control groups (p>0.001), There was…
Significance of nutritional treatment for patients with inflammatory bowel disease in the era of biologics
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease (CD), is a chronic gastrointestinal tract inflammatory disorder. Although its etiology remains unknown, it has been reported that nutrition is involved in the onset of IBD. Patients with IBD often experience malnutrition due to malabsorption and increased energy requirements. Malnutrition is a serious issue for patients with IBD, especially in young people. Growth retardation characterized by delayed skeletal maturation and onset of puberty is a representative complication. In addition, immunosuppression, osteoporosis, and sarcopenia are important issues. Functional foods and diets have been known to alleviate gastrointestinal inflammation by modulating inflammatory cytokines. Furthermore, appropriate nutritional treatment has been reported to be effective on the induction and maintenance of remission in patients with IBD, especially with CD. Conversely, there are negative reports regarding the efficacy of nutritional therapy in patients with IBD. Recently, various new therapeutic agents such as biologics have emerged as key drugs in IBD treatment. In this new era, the efficacy of nutritional treatment, including combination therapy with biologics, should be reconsidered to improve the quality of life in patients with IBD. In this review, the nutritional treatment for patients with IBD is reviewed, and the latest evidence is provided.
Libraries and Mobile Technologies: An Assessment of the Deployment of Mobile Technologies in Libraries
In this study, the researcher examined the views of library users and professional regarding the deployment of mobile technologies in libraries. The researcher tested five hypotheses to achieve the study objectives. The survey research design was used for the study. A total of 250 library users and 250 library professionals took part in the study. The questionnaire served as the instrument for data collection. Both descriptive and inferential statistics were used to analyse the results of the study. All the five assumptions were not supported (p>0.05). Therefore, the researchers conclude that both library users an professionals are aware of mobile technologies, ready to apply them in library services, and are influenced by perceived ease of use and perceived usefulness. The practical and theoretical implications of the results have been explored.
Promoting Library Services in the Social Media Era: Exploring Use, Objectives, Challenges and Perceived Influence
This study examined the use of mediated platforms for creating awareness regarding the services in libraries in Nigeria. The study was guided by five objectives. Descriptive survey was used as the design of the study. Both librarians (n=300) and library users (n=300) were sampled for the study. The questionnaire served as the instrument for data collection. Descriptive analysis like simple percentages, mean and standard deviation were used for the study. It was found that there is low extent of application of social media for the purposes of increasing public awareness of services in libraries. Also, seven objectives of applying social media to enhance awareness of services in libraries were found. Seven strategies for using social media to promote library services were also reported. Six obstacles to the use of social media to promote library services were also reported. The perceived influence of exposure to social media messages promoting library services were also reported. The implications of these results on library practice and scholarship have been explored. Based on the results of the study, the researchers recommends, among others, the utilization of social media to promote library services.