Most Cited

  • Single Oral Dose of Ivermectin as a New Therapeutic Trial for Contacts of Patients with Scabies

    Background: Scabies is one of the common epidemic and endemic diseases worldwide. Many topical therapeutic modalities for scabies are available. Topical ivermectin has been used effectively in treatment of scabies but there is no oral effective therapy that prevents contacts to get scabies. Objective: To evaluate the effectiveness of oral ivermectin in prevention of scabies contacts to get scabies. Patients and Methods: The study is a single-blinded therapeutic study that was conducted in the Center of Dermatology, Baghdad Teaching Hospital, Baghdad, Iraq during the period from April 2018 through October 2019.Two hundred sixty healthy scabies contacts were included in this study, their ages ranged from 5-60 years with a mean ± SD of 19.3± 1.9 years. All these contacts were screened for active scabies and they were all free. The contacts of scabies were treated by ivermectin tablet 200 microgram per kg as a single dose after 2 hours from dinner. They were seen regularly after 4 weeks to be re-examined and to record any scabies and drug side effects. Results: The response after four weeks of single dose therapy of healthy contacts showed that 245 (94%) from 260 were free of scabies and only 15(6%) contacts showed infection with scabies and this was statistically significant Chi-square (c2= 148, P-value less than 0.00000001. No any side effects were noticed in any treated contacts. Conclusion: Oral single ivermectin dose is an effective therapy to prevent scabies contacts to get infection. It an easy method of prevention which is very useful in condition of scabies outbreaks and epidemics to stop the rapid spread of the disease.

  • Keratosis Pilaris Rubra Totalis: Clinical and Histopathological Study with New insights

    Background: Keratosis pilaris rubra (KPR) is a common but unrecognized follicular keratinizatioin. It is a common skin problem among Iraqi population and most cases were misdiagnosed as dermatitis as there are few reports in medical literature. Objective: To do full clinical and histopathological evaluation of KPR in Iraqi population. Patients and Methods: This is case descriptive, clinico-histopathological outpatient based study. It was done in the Center of Dermatology and Venereology, Baghdad Teaching Hospital, Medical City, Iraq during the period from March 2016 to October 2017. Sixty patients were enrolled in this study. History and dermatological examination were carried out for all patients. Skin biopsy was done for 10 patients for histopathological study using Hematoxylin and Eosin stain. Results: A total of the 60 patients were diagnosed as KPR during the study period. Thirty nine (65%) males and 21 (35%) females. The age at onset of disease ranged from since birth to 8 (2.9± 2.17) years . Facial involvement included the cheeks in 60 (100%) patients. Other sites of involvement included the arms where the lateral aspects involved in 60 (100%) patients and the medial aspect 11 (18.3%), thighs including the buttocks in 51 (85%), trunk 25 (41.6%), legs 22 (36.6%) and the neck 15 (25%).The rash was erythematous all over but most obvious on the sides of face presenting as red, rough face. Histopathological evaluation showed follicular plugging in (100%) with dilatation of both superficial and deep vascular plexus in (75%) of cases. Limitation: The main limitation of this study was the lack of follow up data related to the subject of the study. Conclusion: KPR is a common condition among Iraqi population and this study is the largest study carried out all over the world. As most areas of body are involved, the name keratosis pilaris rubra totalis is…

  • Polypoid Collagenous Colitis: A Microscopic Colitis with a Macroscopic Appearance

    Collagenous colitis is a type of microscopic colitis which was originally named based on specific histologic features and the lack of macroscopic abnormalities in the colon. However, there are reports in the literature that describe various macroscopic findings on colonoscopy in patients with histologically confirmed microscopic colitis. We report a case of collagenous colitis that was characterized by a diffusely polypoid colonic mucosa on gross examination of a right hemicolectomy specimen that was performed for a benign neoplasm in a 72 year old man. It is important for endoscopists to be aware of the various macroscopic abnormalities that may be present in this “microscopic” disease.

  • 2019 Coronavirus Disease (COVID-19) Outbreak: A Review Article

    In December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 infections occurred in Wuhan, Hubei Province, China and spread across China and beyond. On February 12, 2020, WHO officially named the disease caused by the novel coronavirus as Coronavirus Disease 2019(COVID-19). The COVID-19 is a respiratory illness caused by a coronavirus and pandemic is now a major global health threat. Coronaviruses (CoV) belong to the genus Coronavirus with its high mutation rate in the Corona viridae. This review focuses to have a preliminary opinion about the disease, the ways of treatment, and prevention in this early stage of COVID-19 outbreak.

  • UPPER GASTROINTESTINAL ENDOSCOPY IN IDO-EKITI, NIGERIA: A FOUR-YEAR REVIEW

    Background: Upper gastrointestinal complaints are common, and the underlying diseases varies widely. Upper gastrointestinal endoscopy is the gold standard investigation for upper gastrointestinal symptoms. It helps in the proper diagnosis and the appropriate management of the underlying lesions. Aim: To determine the characteristics of the patients undergoing upper gastrointestinal endoscopy in a rural community in south-western Nigeria. Methods: This was a retrospective cohort study of all patients who had upper gastrointestinal endoscopy between February 2016 and February 2020 (a period of 4 years). The Age, Gender, Indication and the Endoscopy findings were obtained from the Endoscopy Register. A total of 181 upper gastrointestinal endoscopies had been performed over the period. The data obtained was analyzed using the Statistical Package for the Social Sciences (SPSS) version 21.0. Descriptive statistics used included frequency tables, means and standard deviations. Results: A total number of 181 Oesophagogastroduodenoscopies (OGDs) were performed during the period under review, out of which 95 (52.5%) were males and 86 (47.5%) were females with a male to female ratio of 1.1 to 1. The age range of the patients was 9 to 89 years with a mean(±SD) of 52.4(±1.69) and median of 52.0 years. The highest number of OGDs were performed on individuals within the age bracket of 50-59 years whom were mostly females. Dyspepsia constituted the commonest indication for OGD (51.9%) followed by symptoms of upper gastrointestinal bleeding (haematemesis/melaena) 16.0%, unexplained persistent vomiting 6.6% and clinical suspicion of a gastric tumour 5.5%. The commonest endoscopic abnormality detected from this study was Gastritis 28.2% followed by Gastric erosions 12.2%, Duodenal ulcers 8.8%, Gastric tumours 8.3% and Oesophagitis 7.2%. Normal endoscopy findings were found in 24.9% of the patients. Gastritis was also the commonest endoscopic finding (constituting 40.4%) in patients who had OGD done on account of dyspepsia followed by Duodenal…

  • A Preliminary Study on Constructing the Bed Sounding Data from DEM

    Accurate riverbed information, including riverbed shape, sounding data and elevation data, is needed to simulate the process of flooding in flooded areas by using two-dimensional hydrodynamic model. DEM data is an important feature reflecting topographic changes and plays an important role in hydrological model analysis.However, in the plain area where DEM elevation changes are very small, the extraction and simulation of river network are of low accuracy in the process of hydrologic analysis, and there are great errors in watershed division. Taking the Mihe river basin, shouguang city, shandong province as the research object, based on WMS to abnormal proofreading is smoothing the center line of the river, get in line with the physical meaning of vector river network, the inversion to the original elevation data (DEM), and on this basis, with the river elevation information center line interpolation, construct a sounding data of river model, provide technical support for the two-dimensional hydrodynamic model.

  • Oral Ivermectin should be considered as a Magic Therapy for Scabies with 98% Cure

    Background: Scabies is one of the commonest endemic pruritic diseases all over the worldwide. Many topical therapeutic options for scabies are available, but none of them could be accepted by many patients as all of them need covering the whole body by ointment overnight. Accordingly patients are looking for safe oral therapy like many other diseases. Objective: To assess the effectiveness of oral ivermectin in the treatment of scabies. Patients and Methods: This single, blinded, therapeutic work was conducted in the Center of Dermatology and Venereology, Baghdad Teaching Hospital, Baghdad, Iraq during the period from April 2018 through October 2019. Fifty of patients with scabies were involved in this study. All socio-demographic data that related to the disease were obtained from each patient. History and clinical examination was done for each case to establish the diagnosis. Fifty patients treated by ivermectin tablet 200 microgram per kg as a single dose on empty stomach and repeated after one week. The patients were seen regularly every 2 weeks for 4 weeks duration after stopping therapy, to re-asses cure and to report any local or systemic side effects. Results: A total of 50 patients were included in this study, 21 (42%) males and 29 (58%) females. The ages of males ranged from 5-47 with a mean 20.90±13.034 years; while the age range of females ranged from 3-67 (30.69±18.766) years. At the end of four weeks after stopping therapy , the response to treatment was as follows: Response in 49 (98%) patients and no response in 1 (2%) patients. No cutaneous or systemic side effects were noticed in any patients, while the recurrence or relapse rate was documented in 2 (4%) patients. Conclusion: Oral ivermectin had achieved cure of scabies in 98% of patients, hence it should be considered as a mass treatment in…

  • A Paradigm Synthesis Of The Relevance Of Fieldwork In Geographic Research

    This paper examined the concept of fieldwork and its relevance in geographic studies. In particular, the paper evaluates the pros and cons of fieldwork, and gave reasons why fieldwork is important in geographic research. It was further reiterated that like the laboratory of pure sciences, the field is the laboratory of the geographers as well as other related earth science disciplines because it affords the researcher the opportunity to collect first-hand data and relevant information that may eventually assist in carrying out a reliable research. The stages, benefits and the different approaches to fieldwork are examined. Constraints associated with fieldwork and solutions are provided. It was re-emphasized that although fieldwork is capital intensive and time consuming, early preparations together with a well-articulated aim and objectives, scope and methodology will eventually ensure a successful fieldwork. As a proof of concept, an evaluation of the empirical field studies of Charles Darwin that involved detailed fieldwork in its execution reaffirmed that the field remains a major source of data for any successful geographic research.

  • SPATIAL TEMPORAL ANALYSIS OF RURAL CRIME HOT SPOT ZONE USING GIS: A PART OF COIMBATORE

    Spatio-temporal analysis is one of the suitable method in crime analysis. It is ability to visualize the spatial patterns and control emotionally over a time-ordered sequence of spatial variation. It has been involved the spatial modeling and models of location- allocation, spatial interaction, spatial choice with search, spatial optimization and space-time. Spatio-Temporal Analysis of Crime (STAC) is a powerful tool to identify the crime patterns and detect the crime hot clusters in identifying the hotspot areas. The aim of the objective study is to analyze the spatial effects based on space and time difference among the divisions (space and time) and rate of change. The different types of crime occurrence data were collected from fourteen rural police jurisdiction (2003-2006) in Coimbatore district, TamilNadu. For this analysis, crime occurrence data were used through ArcGIS 10.2 version. The study was analyzed the random walk incidences, and moving path of the peak incidences which are effective models used for entire surrounding area. The study was concluded that spatial-temporal dimension of crime in rural police jurisdictions and explaining how these outcomes used to assist the advance development of crime prevention strategies.

  • Ganglion Impar block through Transsacrococcygeal Approach For Management Of Chronic Perineal Pain

    The ganglion Impar is an unpaired sympathetic structure located at the level of the Sacrococcygeal joint. The modified technique replaced the previously using technique of the Impar block via the horizontal approach through the anococcygeal ligament. Modified technique of Ganglion Impar block through transsacroccygeal approach is easy to perform and give maximum pain relief with margin of safety. Aims and objectives To study, 1) Ease and complications of Impar block through trans- sacrococcygeal approach 2) The analgesic efficacy of Impar block, 3) Duration of analgesic effect of Impar block Method In this retrospective study,15 patients who had chronic perineal pain had given ganglion Impar block.., The ganglion Impar block was given through trans-sacrococcygeal approach, After written and informed consent, patient was asked to lie down on his abdomen, facing down with a pillow under the pelvis to help flatten out the lower lumber spine’s natural curvature. Skin was infiltrate with local anaesthetic, after proper aseptic precautions. The needle is advanced under fluoroscopy guidance until correct needle placement is obtained. Once position is confirmed, therapeutic block is performed with administration of 2ml of 100% absolute alcohol after confirming 50% reduction in VAS from baseline with diagnostic block (0.125% Bupivacaine 5 ml). Attempts of procedure were recorded in all patients. VAS was assessed after 12 and 24 hours. Patients were discharged after 24 hours, asked to report every week and whenever VAS is more than 4 for 3 months Result Fifteen patients with advanced cancer with perineal pain who were not responding to pharmacotherapy treatment received a neurolytic ganglion Impar block through trans-sacrococcygeal approach. Thirteen Patients were not needed any medication. Two patients were needed Tab Morphine after 2 weeks of block. All the blocks were effective without any adverse events. All the patients had significant pain relief during 3 months follow…