Introduction Crowned dens syndrome (CDS) is a rare clinical presentation of chondrocalcinosis or calcium pyrophosphate crystal deposition (CPPD) disease, characterized by fever, neck pain and stiffness, associated with increased biological markers of inflammation. Diagnosis is made mainly via imaging, and the best modality remains the magnetic resonance imaging (MRI) of the neck showing calcification and calcium pyrophosphate crystals deposition around the odontoid process (1). The aim of this report is to increase awareness of this rare and ill-known clinical tableau and to review its complications and the latest modalities of its diagnosis and treatment. Clinical case: An 83-year-old female patient presented to the emergency department (ED) of the Middle East Institute of Health (MEIH) with severe acute onset neck stiffness and pain of 10/10 intensity, radiating to the submandibular area and reaching the occipital part of the head, associated with nausea and 2 episodes of chills one day prior to presentation. Patient denied any recent history of trauma or surgery of the head and neck. Physical exam at that time was only remarkable for marked limitation of neck motion, and positive Kernig and Brudzinski signs. No skin changes, facial sinuses tenderness, cervical lymphadenopathies or neck swellings were noted. Vital signs at ED were within normal range except for a low grade fever. Laboratory work-up upon presentation showed hyperleukocytosis (WBC = 14000/mm3) with left shift and a C-reactive protein (CRP) of 189 mg/L (0-5 mg/L). Chest X-Ray only showed degenerative osteoarthritis of the thoracic spinal vertebrae. CT-scan of the brain without IV contrast done urgently showed no acute changes. As Clinical and biological features were suggestive of acute meningitis, cultures were taken including blood, urine and CSF fluid from lumbar puncture. The patient was admitted to the hospital for IV antibiotic treatment with a large spectrum carbapenem and close observation. On…
HPLC profiling, in vitro antisickling and antioxidant activities of phenolic compound extracts from black bean seeds (Phaseolus vulgarus L.) used in the management of sickle cell disease in the West Region of Cameroon
Natural molecules from food have been used to manage sickle cell crises. As a genetic blood disorder, treatment is complex and expensive. This study was carried out to establish the phenolic compounds profile of black bean seeds (Phaseolus vulgarus. L) commonly used by some families in the Western Region of Cameroon to manage sickle cell disease and to evaluate their in vitro antisickling, membrane stability and antioxidant properties. Free, bound and total phenolic contents were estimated to be 0.1±0; 0.108±0 and 0.212±0 mg EAG/g of sample respectively. Free phenolic compounds contain ferulic acid (0.013 μg/g), while bound phenolic compounds contain gallic acid (2.13 μg/g) and ferulic acid (0.037 μg/g). Free phenolic compounds had the higher rates of inhibition (82.26±2%), reversibility (69.86±3%) of sickling and the best effect on membrane stability of erythrocytes. Phenolic extracts from black bean seeds also showed a high global antioxidant activity with free phenolic compounds (28.42± 0 mgFeII/100g). Total phenolic compounds showed a better activity on DPPH radical with a IC50 of 2.42±1µg/µL while free phenolic compounds showed a better activity on scavenging hydroxyl radical with a IC50 of 1.5±0.5µg/µL. These results may justify the use of black bean seeds by sickle cell patients from Cameroon.
Digital games can help older adults to entertain themselves, socialize with others, engage their cognitive functions, and enhance emotional states. This study surveyed 463 older Canadian adults to identify the digital games they had played and investigate whether playing them was associated with perceived socioemotional and cognitive benefits. The most widely reported socioemotional benefits were developing self-confidence, dealing with loneliness, and connecting with family. The most widely reported cognitive benefits were focusing, memory improvement, improved reaction speed, and problem solving. In the socioemotional category, connecting with current friends and connecting with family were both associated with strategy games, while connecting with current friends was also associated with sport games. In the cognitive category, both problem solving and speed in reacting/responding were associated with arcade games. Results show that playing digital games has the potential to be an intervention tool to improve older adults’ wellbeing. Funding: This study was supported by the Social Sciences and Humanities Research Council of Canada (grant number 435-2012-0325) and AGE-WELL NCE Inc., a member of Canada’s Networks of Centres of Excellence (grant number CRP 2015-WP4.2).
Background: Aging as a natural physiological process is accompanied with nutritional and metabolic changes that is reflected by the anthropometric indices furthermore loss of muscular and fat masses rises. elderly individuals it is complex, and sometimes impossible, to measure standing height precisely because of standing straight difficulties arising from underlying mobility issues Anthropometric indices and measuring formulas are greatly trustworthy when compared with more sophisticated methodologies such as hydro densitometry, electronic bio impedance. Aim: To assess which one of the three anthropometric measures (demi-span, ulna length and knee height) is the most accurate for height estimation in Egyptian elderly males, and to provide a nationally representative regression equation for stature prediction that could be applied to Egyptian elderly males. Methodology: A cross sectional research study was conducted to estimate height in community dwelling Egyptian ambulant elderly males. The study sample consisted of 226 community dwelling elderly males. Results: The model for using knee height to estimate standing height of Egyptian elderly males [Height = 57.345 + 2.131 (Knee height in cm)], was found to be statistically significant reflecting 63.3% of standing height changes. [Table (5)] Besides there was strong statistically significant positive correlation between measured standing heights and study predicted standing heights (P value < 0.001). [Table (6)] Finally it was revealed and displayed that by using the study equation, there is no statistically significant difference between measured and predicted heights. Conclusions: In the current research study, knee height was found to be more accurate than demi-span and ulna length for estimating height of Egyptian elderly males.
A survey of South African plant species used for the treatment of “u wela” in Venda culture, Limpopo Province
Medicinal plants are widely recognized as the key component for critical human health, social and economic support. The current study was conducted to identify medicinal plants used by local people and traditional healers to treat “u wela” in Vhembe District, Limpopo, South Africa. A questionnaire was designed to gather information on the local names of plants, plant parts used and methods of preparation administered by the traditional healers. Plant species were collected based on indigenous knowledge of local traditional healers through the use of a questionnaire and personal interviews, and some were identified using literature and herbarium at the University of Limpopo. The study revealed that thirty-seven medicinal plants are used for treatment of “u wela” in the study area. The frequency index was calculated and the highest frequency was observed in Elaeodendron transvaalensis Jacq (47%) and the least were found in Albizia versicolor Welw. Ex Oliv (6%). Some medicinal uses of identified plants which have not been recorded in the consulted literature were documented. Noticeably, many of these plants were grown in the wild. Traditional healers use different plant part(s) for the treatment of various ailments. Roots (40%) were highly used followed by 20%, bark (13%) and leaves. The plant forms used were trees, (38%), shrubs, (3%), climbers, herbs and succulents (4.7%) belonged to the herbs and succulents. The results stipulated that a high population of people in the community still relied on traditional medicine for their primary health care.
Travel behavior characteristics in Nigeria’s most commercialized urban development: a Study of Eti-Osa Local Government, Lagos Nigeria
Globalisation has enhanced the rate of urbanisation and influenced the travel behaviour characteristics across the cities of the world. Remarkably, in the case of Nigeria, especially in the most commercialised local government area, the travel pattern seems erratic and unpredictable; problems associated with urban mobility include delay, traffic congestion, and chaotic trip pattern characteristics. In this regards, most related studies seems to be biased towards the developed economics urban metropolitan areas. Therefore this study intends to examine the travel behavior characteristics in Nigeria’s most commercialised local government area. The methodology involves both the qualitative and the quantitative methods. The data is analysed with descriptive, chi-square statistical and regression analytical techniques. The study reveals that socio-economic characteristics especially gender, and the female to be specific contributes more to the volume of trips in the study area than the men. In addition, it shows there is a significant relationship between the mode of transport and level of accessibility among the residents of policy.
The Role of Customary Conflict Resolution Mechanisms Among the Oromo: In Case of Dawo District of South West Shewa Zone
This study deals with the role of customary conflict resolution mechanisms in Oromia region with particular emphasis on Dawo district of south west shewa zone. Hence, the (i) purpose of this study was to examine and explore the significance of customary conflict resolution mechanisms in anthropological perspectives in the study area. The (ii) intent of the study was to identify the types of customary conflict resolution mechanisms and cause of conflict in Dawo district. The (iii) purpose of the study was to describe the structure and procedure as well as advantage and disadvantages of customary conflict resolution mechanisms. Finally, the purpose of this study was to provide information to understanding about the study area. To achieve this objective, both primary and secondary data was used. This study applied qualitative data. The data used in this study were generated from one- one interview, focus group discussion, case study and document analysis. In anthropological studies, analysis is an instrument to extract meanings from the information obtained during the field work. In such a manner, data were presented in a qualitative type. By using this methods, the study revealed that conflict in this research area emanate from land issues, theft and competition over resources.
The human population is continuously ageing and previous studies suggest that one’s attitude towards ageing predicts ageing outcome. While several factors have been shown to influence attitude towards ageing, the current study investigated the influence of self-esteem and gender on attitude towards ageing. The study adopted a cross sectional design and a total of two hundred and five (205) civil servants were randomly selected from state Civil Service Secretariats and Local Government headquarters in Enugu, Anambra and Ebonyi states respectively. Self-report measures including the Rosenberg Self-Esteem Scale and a Self-Developed Attitude towards Ageing Scale were used for data collection. A Two-Way Analysis of Variance was used for the data analysis. The findings revealed that our first proposition that self-esteem as a psychological mechanism will significantly predict attitude towards ageing was not supported meaning that self-esteem whether high or low does not matter in how individuals respond to ageing consciousness. Whereas, the second proposition that gender will greatly influence attitude towards ageing was confirmed. In other word, the result further confirmed that female show more positive attitude about ageing than the male. The findings are discussed.
ANTICANDIDA ACTIVITY OF ETHANOL EXTRACT JERINGAU (Acorus calamus L) RHIZOME AGAINST Candida albicans ISOLATE REMOVABLE FULL DENTURE ACRYLIC
Background: Maintaining denture hygiene by brushing and soaking it in disinfectant can prevent Candida infections. Jeringau (Acorus calamus L) is an herbal plant that its rhizome extract has antifungal activity against Candida albicans. Aim of study: This study aimed to measure whether the value of minimum inhibitory concentration (MIC50) of ethanol extract rhizome of Jeringau against C.albicans isolates the maxillary removable full denture acrylic. Materials and methods: Rhizome of jeringau was prepared. In vitro, study was conducted laboratory experimentally with ten samples tested by serial dilution ethanol extract rhizome of jeringau method with eight different concentrations. They were dropped to 0,1 ml C. albicans and incubated at 37 oC for 24 hours and repeated twice. They were grown on Sabouraud Dextro Agar medium that were incubated and seen its growth. Results: Inhibition zone extract of rhizome jeringau concentration 100% on plate I (9,4 mm) and plate II (8,85 mm). MIC50 of ethanol extract rhizome of jeringau is 2,5 mg/ml. Conclusion: Rhizome of jeringau containing β-asarone which is the major active component of antifungal against C. albicans. It was terpenoid group. Terpenoid caused porin damage. When porin was broken it would reduce the permeability of fungal cell wall resulting in fungal cells would lack of nutrients, thus the growth of fungi was inhibited
This quantitative study attempted to understand the factors that influence students at the large university in south-eastern United States to pursue Information Technology (IT) certification. The study investigated the problem of determining the factors that influence college students to pursue IT certification along with their academic degree and thereby increase their chances of gaining employment and increasing completion rates for the college resulting in increased state funding. This influence may lead to higher job placement after graduation resulting in an increase in completion rates for each college. The results showed that 91.7% of the respondents were inclined to take the certification exam if it means job security. Of all the participants, 88.4% indicated that they would take the certification exam if their future job requires it. A statistically significant difference was found between students’ rank and their perception on the statement “Schools prepare me for the certification exam.” A statistically significant difference was also found between students’ GPA and their perception on the statement “I am inclined to take the certification exam if I get reimbursed for my testing fee after passing the test.” The goal of the study was to provide information that can be used to improve students’ perceptions of the importance of certifications as well as to identify and address weaknesses in curriculum and/or interaction with students that can be addressed to improve students’ perceptions related to the importance of certificates. It also created a foundation for administrators and instructors in IT programs throughout the educational system to influence students in pursuing IT certification.