A Systemic Review on the Pharmacognosy, Phytochemistry, Pharmacological and Clinical aspects of Edible stemmed vine, Cissus quadrangularis L
Cissus quadrangularis Linn. belonging to the family Vitaceae is a common perennial climber, which is distributed throughout India. This square stemmed vine is widely used in traditional systems of medicines and parts like stem, roots and shoots are the most important parts, which are used medicinally. The article reveals a wide number of phytochemical constituents that had been isolated from the plant, which plays major role including gallic acid derivatives, steroids, iridoids, flavonoids, stilbenes and triterpenes, which possesses activities like anti inflammatory, anti tumor, gastro protective, antioxidant, antimicrobial and various other important medicinal properties. Many extensive research works had been done to prove its biological activities and pharmacology of its extracts. The current review deals with the enormous amount of updated information of scientific research and reports available in different aspects of this plant involving phytochemical, pharmacology, toxicological and clinical works. This review also includes reports on pharmacognosy, variants and traditional medicinal uses of the plant.
Fluid resuscitation is the cornerstone of treatment for pediatric shock caused by conditions such as sepsis, dehydration, trauma, and anaphylaxis. Children presenting to the Emergency Department (ED) in shock have a high risk of mortality, and each hour of delay in shock reversal doubles the odds of death1,2. Pediatric Advanced Life Support (PALS) guidelines emphasize the importance of providing rapid fluid resuscitation to prevent the progression to hypotensive or refractory shock3. PALS and other septic shock guidelines recommend that patients receive a 20 mL/kg bolus of crystalloid immediately upon recognition of hypovolemic or distributive shock, with 20 mL/kg to be delivered within 5 minutes and up to 60 mL/kg within the first 15-60 minutes3-6. Studies based on these guidelines show that earlier fluid delivery directed at reversal of shock reversal leads to decreased morbidity7-9, mortality2,7,9-12, and hospital length of stay (LOS)9,11-13. Unfortunately, timely fluid delivery is often not achieved due to the technical challenges of obtaining adequate vascular access and delivering fluid boluses quickly in patients with shock or hypotension11,14-16. Current methods of fluid bolus delivery in the pediatric emergency care setting include infusion pumps, gravity drip, pressure bags, rapid infusers, and the push-pull syringe technique17,18. Each of these methods are limited by speed, ease of use, or safety concerns. Infusion pumps provide a maximum rate of 999 mL per hour, which for a 25kg child would provide a 60 mL/kg bolus in 90 minutes. In most patients, infusion pumps are therefore too slow to provide adequate fluid resuscitation. Gravity drip rates are unpredictable and inadequate for the treatment of shock and hypotension. For example, up to 50 minutes are required for one liter of fluid to flow through a 22G intravenous (IV) line, and up to 200 minutes via the intraosseous (IO) route19-22. A pressure cuff may speed flow…
The concept of beauty in the world is certainly influenced by ethnicity and cultural factors, but generally harmony, balance and simmetry are common characteristics positively considered by every population. Logical Beauty Harmony is an innovative System for using filler and botulinum toxin in aesthetic medicine based on Natural Shape zones (NS zones). These compartment consist of strategic sequential injection areas that allow creating, improving or restoring adequate volumes, guaranteeing natural results and expressiveness. Starting from the recent acquisitions of Functional Anatomy, Physiology of Aging, Product Rheology and considering the objective analysis of the characteristics of harmony of each individual we have developed an approach that uses injectables in a targeted way using Support and Lifting vectors at the level of Upper, Middle and Lower Third of the face, injecting first deep and then passing to the surface. The face is divided into vertical and horizontal proportions. These simply but fundamental principle of facial proportion, modified by recent anthropometric studies, have found their way into the teaching and practice of cosmetic facial medicine and surgery. The series of data that can be detected by applying the previous parameters offers the chance of identify the variants that the face can present, so as to make eventually those changes that lead closer to the ideal model. In planning the treatment, the study of the different parameters, proportions, lines, ideal movements and angles linked to the comparison of the measurements of the different parts of the face will be more useful in determining type and extent of the corrections to be made. 9 treatment protocols for the face have been precisely established.
Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease which carries many challenges in the process of diagnosis. A 73 years old female was evaluated for exertional dyspnea with CXR PA evidence of bilateral upper lobe fibrosis and pleural thickening. HRCT revealed typical features suggestive of PPFE. Lung biopsy was not performed considering the risk. Though it is rare PPFE should be considered when evaluating bilateral apical fibrosis. Proper radiological evaluation is paramount important in the process of diagnostic evaluation. Performance of lung biopsy as an essential criterion should be reconsider with associated risks.
Potato has been widely planted, and China’s potato planting area and total output have become the first in the world. As an important part of the whole mechanization technology, potato planting mechanization directly affects the quality and yield of potato. As the core component of potato planter, the performance of seed metering device directly affects the operation quality of planter. In recent years, with the continuous efforts of researchers and manufacturers at home and abroad, the types and research technology of seed metering device are constantly innovating and improving. This paper mainly introduces the key technologies and types of seed metering devices used in the main models in China and abroad, as well as the existing problems and future development direction of different types of seed metering devices.
Study of Mechno- luminescence, thermoluminescence properties of solid state reaction derived Ce3+co-doped Ca2MgSi2O7:Eu2+ microphosphors and application for mechnoluminescent display device technology.
In this paper, we discuss a series of ce3+ co doped di calcium magnesium di silicate phosphors were synthesized by high temperature solid state reaction method. Thermoluminescence properties of prepared sample also investigated. Their kinetic parameters [activation energy (E), frequency factor (s) and order of the kinetics (b)] of these phosphors were evaluated and compared using the peak shape method. FractoMechno- luminescence properties Ca2MgSi2O7: Eu2+ and Ca2MgSi2O7: Ce3+, Eu2+ phosphors. Their ML properties showed that when Ca2MgSi2O7: Eu2+ phosphor is co doped with Ce3+, ML intensity was more (strongly) enhanced and their mechanoluminescence intensities of Ca2MgSi2O7: Eu2+ and Ca2MgSi2O7: Eu2+, Ce3+ phosphors increased proportionally increased with the increase in impact velocity, which suggests that these phosphors can be used as mechnoluminescent display device such as fracture sensor, impact sensor, damage sensors, safety management monitoring system etc .
COVID-19 outbreak has been a serious threat and it has been reported with different presentations and complications, here we report a 39 year old healthy male who presented with respiratory symptoms and investigation revealed that he is positive for SARS-CoV-2 and work up for Leukocytosis confirmed the diagnosis of CML.
Understanding Health Professionals about Preservation of Silence in the Intensive Care Unit During the Post-Heart Surgery Surgery: a Systematic Review
Introduction: Through studies in the scientific literature about the measurement of sounds in the Intensive Care Unit environment, it is clear that the noise, continuous sound of equipment and those caused by the health team itself is excessive and above 85dB (decibels), favors increased sensitivity of patients to pain, irritation, post-traumatic stress and may cause psychomotor agitation, delirium, changes in heart rate and sleep. A peaceful environment can bring countless benefits to restoring the health of patients, as well as reducing the stress of professionals. Objective: To analyze some research and studies published in Brazil about the noise in an Intensive Care Unit and the perception that professionals have about this topic. Methods: A systematic literature review was performed with electronic search of articles indexed in PePSIC and SciELO databases, published from 2009 to 2019, in which the inclusion and exclusion criteria were considered. Results: indicate that the noise in this type of place often presents with an oscillating intensity of moderate to intense. It is verified that there is from the professionals a certain level of understanding of the existence of noise in the ICU. Considerations: Despite the finding by professionals about noise, it is also observed that there are few current publications about the awareness of health professionals regarding the importance of preserving a quieter environment and criteria that reinforce effective humanization interventions during the study. postoperative period of cardiac surgery in this type of environment.
The use of medicinal plants and probiotics has recently gained interest since the ban on the use of antibiotics as growth promoters by the European Union in 2006. They are new alternatives to bridge the gap between food safety and production. Medicinal plants are cheaper and loaded with several minerals, vitamins and phytochemicals such as: alkaloids, saponin, flavonoids, phenols, tannins etc. which allows them to perform multiple biological activities. Probiotics on the other hand, repopulates the gastro intestinal tracts (GIT) with beneficial bacteria which controls the action of pathogens and control their population, thereby reducing mortality and improving general performance of an animal.
Introduction: The Intensive Care Unit is a hospital location permeated by not very positive associations, with the multidisciplinary team having to deal with the pain, fears and anxiety of their patients daily and the demands of their families for comprehensive care and less suffering for the patient. Pain is a reaction of the patient with biopsychosocial factors involved. The team does not always act successfully in the face of the patient’s pain, using the psychologist as a mediator of this situation. Objective: to reflect on the role of the psychologist in the face of the patient’s pain in the Intensive Care Unit. Methodology: experience report. Results and discussion: In the intensive care unit, the patient is distant from his family members, without clothes, with monitoring of different equipment and people, with invasive care, which can be felt as threatening his integrity. Pain is an unpleasant sensory experience that may be associated with tissue damage or not. It is a difficult phenomenon to be measured, since it can be an emotional pain, activated by psychological components or not. Each person has a different intensity, manifestation and reaction to pain. There are pain scales that can be used as a strategy to adapt the best intervention in different contexts of illness. The psychologist in this unit acts focused on the patient, his family and team, because everyone involved may be interfering in the recovery process and in the experience of pain and in its coping. In this triad, attentive, neutral listening should be offered to provide psychological support and to facilitate the mediation of these relationships. Conclusion: This study points to the need to study more about the pain process in the ICU context, the role of the psychologist and the importance of humanization in this context.