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  • Novel urease inhibitor

    Urease, also known as urea amide hydrolase, contains two metal nickel ion active centers that catalyze the decomposition of urea to ammonia and carbon dioxide. Urease is widely found in nature, including plants, animals, and microorganisms, and greatly affects the utilization of nitrogen-containing nutrients by plants and animals. At the same time, its content can also affect the normal physiological metabolism of microorganisms, which in turn affects the survival rate of microorganisms. It can be seen that the role of urease inhibitors is very important. Urease inhibitors, such substances, can affect or even inhibit the activity of urease by direct or indirect means. Guided by computer-aided drug design, the team developed two new urease inhibitors, which are low-cost, non-toxic to plants, animals and humans, and environmentally friendly urease inhibitors. After experimentally measuring the activity of urease inhibitors, the two urease inhibitors have stronger inhibition ability than the widely used acetohydroxamic acid on the market.

  • The Basic Nature and analysis of Ganoderma Lucidum

    Ganoderma lucidum has been a well-known herb since ancient times and has the reputation of “Xiancao”. In modern times, Ganoderma Lucidum is used more in nourishing health products. Chinese medicine believes that Ganoderma lucidum is sweet, flat, and beneficial to qi and blood. It has the effect of soothing the mind, strengthening the spleen and nourishing the stomach. Clinically, it is also often used to treat insomnia, fatigue, and asthma. The Ganoderma lucidum real estate area has changed greatly from ancient to modern. The wild production area has changed from the ancient Wuyue Mountain to the current major lakes and seas. The cultivation of Ganoderma lucidum began in the 1950s, and the production area has changed to today’s Hubei, Hainan and other places. Currently cultivated Ganoderma lucidum. Has become the main body of Ganoderma lucidum. Hubei is an important real estate area. This paper mainly summarizes and analyzes the original plant and growth environment, cultivation techniques, pest control, medicinal properties, chemical composition, pharmacological effects and clinical use of the existing Chinese herbal medicine Ganoderma lucidum. From the research on the origin, traits, growth habits, medicinal properties and clinical application of Ganoderma lucidum, it provides practical information for the cultivation, use and pharmacological properties of Ganoderma lucidum. At the same time, the summary and analysis of Ganoderma lucidum information will be conducive to further research on the efficacy and marketization of Ganoderma lucidum.

  • Analysis of the Conversational Implicature of Violating Cooperative Principles in Daily Discourse

    Conversational implicature and conversational principle are proposed by the American language philosopher Grice. The principle of conversation is an important part of the study in the field of pragmatics, represented by Grice’s Cooperative principle and Leech’s Politeness principle, which constitutes the main reference principle and basis for understanding the meaning of conversation. To a certain extent, they regulate people’s verbal communication behavior. Grice believes that in the process of people’s communication, the two sides of the dialogue seem to follow a certain principle intentionally or unintentionally in order to complete the communicative task effectively. But sometimes, to make the communication activities go smoothly, the communicative parties usually break the cooperative principles in order to achieve some kind of communicative purpose. Based on the daily communicative dialogue as corpus, this paper analyzes the communicative implicature that violates the principle of conversation. Through the analysis of communicative implicature and pragmatic effect to explore the main forms of conversational implicature in verbal communication in the context of real communication.

  • Multimodal Discourse Analysis of Coca-Cola’s Print Advertising

    With the development of the Internet, the expression of information is not limited to words, but it develops into other modes, such as images, sounds, actions, etc. This study is based on the visual grammar. The visual grammar proposed by Kress and Van Leeuwen is based on Halliday’s systemic functional linguistics. Coca-Cola as a popular soft drink brand, its graphic advertising design can be said to be very mature and representative. This study is based on visual grammar to carry on the thorough analysis to the American Coca-Cola classic print advertisement, carries on the analysis to each print advertisement from the reproduction meaning, the interactive meaning and the composition meaning. The following conclusions can be drawn: 1. In the Coca-Cola print advertisement in the United States, the professional characteristics of the characters are obvious. 2. Advertising language can directly express the benefits of the product. 3. The combination of image mode and language mode in the Coca-Cola print advertisement can be explained by visual grammar.

  • Getting Rid of “Bomb Pushing the Womb”: Dysmenorrhea Management

    As indicated by the American Academy of Family Physicians, up to 20% of women experience the ill effects of menstrual cramping extreme enough to meddle with every day exercises. On the off chance that prostaglandins levels are higher, more pain is regularly connected with the issues. Cycle length, blood misfortune, period-related symptoms, liquid shading, and consistency are on the whole profoundly factor, notwithstanding for only one individual. Be that as it may, serious menstrual pain is probably going to be brought about by a medical problem, for example, PMS, fibroids, or endometriosis and needs medical help. At the point when scientists examined recurrence and span of exercise and contrasted it with reports of period pain, they discovered exercise did little to lessen discomfort, and in truth this persevered notwithstanding when a scope of different components—including weight, ethnicity, smoking and utilization of the birth control pill—were mulled over. A few women may likewise incline toward not to utilize hormonal contraceptives, as they can bring undesirable reactions, for example, variances in weight and disposition. A few strategies can likewise somewhat raise the danger of specific cancers, including bosom cancer (despite the fact that they diminish the danger of others, including womb cancer).

  • Supplements and Enhancement Drugs: Athletes Torment Themselves with Potential Risks

    An individual’s dietary and supplement strategies can influence markedly their physical performance. Issues related to knowledge of nutrition and dietary supplementation (DS) are understudied in professional athletes. Supplements nowadays are used with the aim of improve body composition, of which the origins are multiplex in structure. Many approaches to improve the response to resistance training are the use of pre-/post-/in between workout nutritional interventions; with beverages garnering significant interest. The health benefits and risks of dietary supplement use are controversial as there is no visible immediate benefits observed. Sports nutrition recommendations for endurance exercise however remains a complex issue with often opposing views and advice by various health care professionals. Many athletes, at all levels of competition, place great emphasis on the use of dietary supplements, but of all the factors that determine athletic performance, supplements can play only a very small role. Compared with factors such as talent, training, tactics, and motivation, nutrition has a small effect on performance, and supplements can be no more than a minor part of the athlete’s nutrition strategy.

  • Assessment of Transport and Logistics Education among Selected Universities in Southwestern Nigeria

    This paper assessed the Transport and Logistics Education as a University undergraduate programme being offered by some selected universities in Southwestern Nigeria. The specific objectives of this study are to examine the programmes of transport and logistics education with a view to understand areas where they are lagging behind across the selected Universities. Secondly, to determine those attributes that may facilitate qualitative education, not only in transport sector; but also at improving Nigerian universities education system. The total of 250 recently graduating students of the selected universities were randomly sampled and given both questionnaires and assessment form which covers six major subjects in the areas of Logistics and Transport. Descriptive analytical technique was used to achieve the first objective and Principal Component Analysis (PCA) was used to factorize fifteen identified variables and reduced it to eight principal components considered to facilitate qualitative education in Transport and Logistics Education in Nigeria. The results showcased the areas of strength and weaknesses of the selected schools and principal factors that must be available for qualitative logistics and transport education system in Nigeria.

  • Complimentary Care: Non-Pharmacological Pain Management

    Aristotle (4th century B.C.) described pain as emotion, being the opposite of pleasure. Whereas, Buddha stated “Pain is the outcome of sin”, as evidence that an individual was possessed by demons. In some religions it is the cost of attachment. Spiritual counseling thus may be more of a priority than medical management. Many non-physiologic factors (psychological, familial and societal attitudes, life stressors, and cultural or spiritual) contributing to the experience of and response to pain. Emotional stress such as anxiety and depression play a key role in experience of pain. Chronic pain is associated with increased levels of depressive symptoms, anxiety, and insomnia regardless of disability status. it has both modifiable factors (mental health, co-morbidities, smoking, alcohol, obesity, physical activity/exercise, sleep, nutrition, economic status and occupational) and non-modifiable factors (age, sex, cultural and socioeconomic background, history of trauma/ injury/ interpersonal violence, heritage). The relationship between increased BMI and chronic pain in adults seems intuitive and may be related, in part, to increased weight-bearing on joints, reduced physical activity and deconditioning. Patient with physical disabilities may have co-occurring chronic pain, but the prevalence and specific associated factors are unknown. Neuropathic pain (NeP) can be the result of a variety of conditions, including metabolic disease, infection, malignancy, trauma, medications, and toxins; estimates of 60% among those with chronic pain. Chronic pain affects 20% of the European population and is commoner in women, older people, and with relative deprivation. Its management in the community remains generally unsatisfactory, partly because of lack of evidence for effective interventions. Also, family and caregivers’ beliefs and attitudes towards pain, either positively and negatively to tolerate and express pain are important. Risk factors include socio-demographic, clinical, psychological, and biological factors. Pain increases depression risk 3-5-fold. Pain, rather than chronic disease, is associated with the recurrence of depressive and…

  • Psychiatric Pharmacy: New role of Pharmacists in Mental Health

    Psychiatric disorders are one of the major causes of global burden of diseases. Stigma remains a major impediment in the delivery of mental healthcare. It has been found across various studies that attitudes of doctors of other specialties and other healthcare professionals also contribute to stigma due to their lack of knowledge and awareness about psychiatry and mental health problems. The number of mental health professionals remains abysmally low. Community pharmacists are accessible, knowledgeable, and capable of providing mental health promotion and care in communities. This may not be a role that is recognized by the public, and men in particular. However, psychotherapy paired with medication is the most effective way to promote recovery. Examples include: Cognitive Behavioral Therapy, Exposure Therapy, Dialectical Behavior Therapy, etc. Pharmacists can play a key role by providing mental health medication management support to improve access and address patients’ mental health needs.

  • Arts and Science of Athletic Performance

    Athletes utilize numerous strategies to reduce body weight or body fat and to increase stamina prior to competition. Personalized nutrition in athletic populations aims to optimize health, body composition, and exercise performance by targeting dietary recommendations to an individual’s genetic profile. Additionally, athletes’ nutritional requirements may vary widely depending on sport, position, timing of season, and training vs rest day. Bodily hydration during sporting activity is one of the best indicators of health in athletes and can be a limiting factor for sport performance. Treatment for athletes is primarily to increase energy availability and often requires a team approach including a sport physician, sports dietitian, physiologist, and psychologist. Maximizing athletic performance is a passion that athletes, coaches, athlete support professionals, and sports scientists share. A thorough understanding of the basics of all aspects of human physiology and the ability of the body to adapt to the environmental stress of exercise training is the foundation we use to explain the incredible athletic and sport performances that are commonplace in today’s world.