In literature we see clear evidence of Angiotensin Converting Enzyme inhibitors (ACEI’s) causing visceral angioedema, but further evidence is required to establish the causality for Angiotensin Receptor Blockers (ARB’s). With the widespread usage of these anti-hypertensives and the potential serious adverse effect in the form of angioedema; clinicians should consider medication induced as part of their differentials.
Carcass Quality, Nutrient Retention And Caeca Microbial Population Of Broiler Chicks Administered Rolfe (Daniellia Oliveri) Leaf Extract As An Antibiotic Alternative
The study was designed to evaluate the carcass quality, nutrient retention and caeca microbial population of broiler chicks administered Daniellia oliveri leaf extract (DOE) as an antibiotic alternative. A total of 250 – one-day-old broiler chicks (Ross 308) were allocated to five treatments in a completely randomized design and each treatment group was further sub-divided into five replicates containing ten (10) birds each. Treatment 1 (Control) was given 1.20 g/ liter of Neomycin in water, while treatments 2, 3, 4 and 5 were given DOE at 10 ml, 20 ml, 30 ml and 40 ml/liter of water respectively. Clean feed and water were supplied ad libitum throughout the experiment which lasted for 56 days. Data collected were used to determine the carcass quality, nutrient retention and caeca microbial population. Highest dressing percentage was recorded for birds in T5 (70.0%) followed by T4 (69.08 %), T3 (67.18 %), T2 (67.44 %) and T1 (65.0 %) respectively (P
Residue trials of deltamethrin in black pepper (Piper nigrum) were conducted to estimate the maximum residue limit (MRL). Five residue trials were conducted at three commercial growers’ plots in Johor, Perak and Sarawak (Malaysia). The study plots contained 120 mature pepper vines which were selected and treated with deltamethrin using the manufacturer’s recommended rate (0.01 kg a.i./ha). The insecticide was applied with a motorized sprayer on monthly intervals. Green pepper berries samples (500g) were randomly collected from the plots at 1, 3, 5 and/or 7 days after the last spray. Analytical procedure of deltamethrin extraction was validated prior to actual analysis. Satisfactory recoveries ranging from 86.2% to 110.2% were obtained for the fortified pepper berries samples. The limits of detection and limits of quantification for deltamethrin were 0.521 μg kg−1 and 1.63 μg kg−1, respectively. Results showed that deltamethrin residues were at the low level with the residue value ranging between
Intrinsic factors affecting incidence of urolithiasis in diabetic patients –A preliminary case-control study
There has been a steep rise in incidence of urolithiasis in recent years. Recent studies have revealed an increased prevalence of urolithiasis in patients with Diabetes Mellitus (DM). The role of various intrinsic factors of diabetic patients such as Body Mass Index (BMI), level of glycemic control, baseline kidney function and mode of treatment of DM which can influence incidence of urolithiasis still remains uninvestigated. This case control study was taken up to evaluate these intrinsic factors affecting the incidence of urolithiasis in patients with DM. The case group included diabetic patients with urolithiasis and the control group included age matched diabetic patients without urolithiasis. We concluded that Higher BMI and higher serum creatinine level in diabetic patients were associated with increased incidence of urolithiasis whereas other intrinsic factors such as age, sex, duration of DM and the level of glycemic control did not have any influence on it.
Microangiopathic hemolytic anemia/Acquired Thrombotic Thrombocytopenic Purpura as a first presentation of pancreatic cancer
Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening hematologic disorder. It is mainly characterized by thrombocytopenia, microangiopathic hemolytic anemia (MAHA), fever, renal impairment and neurological abnormality. Plasmapheresis and steroids are the standard of care. MAHA/TTP can be the initial presentation of solid organ malignancies especially gastrointestinal tumors. We report a 56-year-old female patient who presented with progressive back pain, tiredness, easy bruising, fever and weight loss. Laboratory results showed anemia, thrombocytopenia, and schistocytes in the peripheral smear. An initial diagnosis of thrombotic thrombocytopenic purpura (TTP) was made on the basis of clinical presentation and lab findings. She was treated with corticosteroids and plasma exchange but with no major response. CT abdomen and PET CT were suggestive of pancreatic carcinoma with extensive lymph nodal, organs and bone metastases. Supraclavicular lymph node biopsy was compatible with metastatic adenocarcinoma. As a result, the diagnosis of pancreatic cancer was established and the decision was for palliative treatment. This case highlights the need to consider malignancy in patients with MAHA/TTP especially if it does not respond to plasmapheresis. Hence, the treatment of MAHA/TTP could be directed to the underlying malignancy if available.
India being the largest smokeless tobacco (SLT) producer and consumer in the South East Asia Region (SEAR) entitled with a range of products. SLT consumption is very common because it is associated with socio-economic and cultural perspectives in the India. After the implementation of the first treaty of the World Health Organization Framework Convention on Tobacco Control (WHO-FCTC), public health standards were reaffirmed and improvised through successful implementation of articles since 2007 as reported in the global progress factsheet. Many measures have been implemented for achieving the success of WHO-FCTC in India and to control the huge disease burden induced by tobacco use. The objective of the present study was to understand and explore the factors involved in the SLT demand reduction by revealing the dependence and cessation implementation in India in the context of strategies and policies. For this study, we searched for SLT dependence and SLT cessation literature survey in PubMed and obtained 102 literatures consisting of studies and reviews, which were further scrutinized by excluding the reviews, studies conducted abroad and studies conducted within the last 5 years (after 2015). No statistical significance was observed in comparison of National to International SLT dependence and an attempt to quit SLT following the tenure of a year. This is in-line with GATS-2 and international data. We have also discussed a diverse approach in the control of SLT at different levels-such as SLT users, healthcare professional, policy advocates supplier, labeling, legal policies, and educating at various platforms. Effective strategies for the cessation of SLT is mandatory with proper guidance for the manufacturer, users and sellers in controlling SLT products.
World records that two out of six individuals will bite the dust from coronary illness and six out of ten men over age 30 may have indications of coronary illness. The redeeming quality, be that as it may, is heart issues are sensible; furthermore, they can be forestalled, or even switched, with ideal, proficient clinical treatment. A huge number of hazard factors assumes a job in the improvement of coronary illness cigarette, smoking, physical idleness, stress, weight, high blood cholesterol, (hypertension) and diabetes. These components are controllable and not controllable. The most ideal way one can decrease the danger of coronary illness is by limiting, or dodging, the hazard factors-quitting any pretense of smoking, keeping away from liquor, confining salt use, constraining calorie consumption, practicing normally, diminishing enthusiastic pressure, getting observed and researched for hypertension, raised fat, cholesterol and different elements. The initial step, obviously, ought to be meant to bring down one’s hypertension the higher the circulatory strain, the more noteworthy is the danger of coronary episode, stroke and kidney illness. All the more significantly, if any of one’s nearby family members have had hypertension, at an early age, such people ought to be encouraged to have their circulatory strain checked all the time. However it can be miraculously treated by homeopathy
Performance, Haematology And Serum Biochemical Parameters Of Growing Grass Cutters (Thyronoyms Swinderianus) Fed Phyllantus Amarus And Pilogstigma Thonngii Leaf Meal Mixture As Partial Replacement For Soya Bean Meal
The objective of the present study was to evaluate the performance, haematology and se-rum biochemical parameters of growing grasscutters (Thrynomys swinderianus) fed Phyl-lantus amarus (PAM) and Pilogstigma thonngii leaf meal (PTM) mixture as partial re-placement for soya bean meal. A total of 35 weaned grasscutters of mixed sex between 5-6 weeks with an average weight of 436.1 and 437.0 g were divided into five groups of 7 animals each and randomly assigned to 5 experimental diets each animal served as a repli-cate in a completely randomized design. The dietary treatments include a control diet with no PATML, T2 (10.0% PATML), T3 (20.0 % PATML), T4 (30.0 % PATML) and T5 (40.0 % PATML) respectively. Feed and water were offered ad libitum throughout the experiment which lasted for 12 weeks. The data obtained was used to evaluate the growth, haematological parameters (PCV, RBC, Hb, MCV, MCH , MCHC, WBC and its differentials ), serum biochemical indices (Albumin, globulin, total protein, creatinine, cholesterol, calcium, phosphorus, ALP, AST and ALT) and fatty acid composition. Aver-age weight gain, average daily feed intake and feed conversion ratio were influenced by the dietary treatments (P
The resettlement projects in Ethiopia have been carried out mainly as a response to extreme problems of drought, food insecurity, population growth and land degradation during the imperial and Derg regime in the 1960’s and 1980’s. The disastrous famine of 1984-85 brought equally disastrous response of Derg government which relocated peasants from famine affected north to the sparsely populated and unoccupied southwest of the country. One of the targeted areas to perform was the Metekel area called Pawie or Beles resettlement site along North Western Ethiopia, originally inhabited by the Gumuz shifting cultivators. The inadequately planned of the Pawie or Beles resettlement site from the 1984-85 was affected the relocated people and the indigenous Gumuz communities. This program resulted Gumuz communities clashed with state sponsored settlers. After a long time tension, the settlers and the host communities formed a bond of relationship known as Wadaj.
The study clarifies the relations of Nile Basin countries after independence. Nile Basin countries are Burundi, Kenya, Rwanda, Tanzania, Uganda, Ethiopia, Eritrea, Egypt, North and newly independent South Sudan. Members of the region are independent in history; politics, economy and geography but tie by the Nile River. Economy determined by the agriculture supported by Pastoralism and agro-Pastoralism among the member countries. Their political development of the region was biased by the colonization and the cold war. From the time when the end of colonization and the cold war, the Nile basin countries can be attained relations in history, politics, economy and geography through the use of Nile Basin Initiative which played a role to the possibilities for cooperation and smooth relations among Nile basin countries.