Demographic and Clinical Characteristics of Epilepsy in Childhood: A Prospective Cross Sectional Study from Sudan

Demographic and Clinical Characteristics of Epilepsy in Childhood: A Prospective Cross Sectional Study from Sudan

Mohamed Osman Omer Dablouk1, Amin Alagib Mohamed Musa1, Ahlam Abdulrahman Hamed2, Rabih Brair Rabih1, Khalid Awad Mohamed3*, Mamoun Mohamed Ali Homeida1

1University of Medical Science and Technology. 2University of Khartoum. 3Weil Cornel Medicine QA.

Background: Epilepsy is a common neurological disorder affecting around 1% of children.  The incidence in Sudan is likely to be higher given the high rate of genetic disorders related to consanguity and acquired disorders caused by CNS infection and birth injury. Epilepsy can be idiopathic or non-idiopathic, symptomatic epilepsy indicates a known cause while cryptogenic epilepsy implies a presumed unknown cause.

Objective: To understand the demographic and clinical characteristics of epilepsy in children in the setting of a tertiary epilepsy clinic in Khartoum, Sudan.

Methods: This is a hospital-based cross sectional study recruiting patients with epilepsy attending a tertiary pediatric neurology clinic. All patients attending the clinic in the 6 month period were included. Data was collected by medical students and was analyzed on IBM SPSS Version 20.0 in a descriptive fashion.

Results: 284 Children were recruited. The mean age for children with epilepsy was 5.74 (range 0-12 Years). Females constituted 59.9%; while 94.7% of patients were of low socioeconomic status. The most common type of seizures found were generalized tonic clinic at 51.8% (147/284), followed by focal seizures at 21.1% (60/284).  71% of our patients (201/284) had no identifiable cause (idiopathic), while 29% were non-idiopathic. Of the non-idiopathic group; 41% were due to congenital anomalies, followed by HIE at 24.1%, infections at 16.9% trauma at 10.8% and tumors at 7.2%. Only 18.3% (52/284) had a positive family history of epilepsy.

Conclusions: There appears to be a higher incidence of epilepsy in Children with low socio – economic status with a slight female predominance. The incidence of idiopathic epilepsy appears to be similar to inter-national figures. We recommend broader community based and long-term studies for better understanding of epilepsy in Sudan.

Keywords: Demographic and Clinical Characteristics of Epilepsy;  Childhood; Prospective Cross Sectional Study; Sudan

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How to cite this article:
Mohamed Osman Omer Dablouk, Amin Alagib Mohamed Musa, Ahlam Abdulrahman Hamed, Rabih Brair Rabih, Khalid Awad Mohamed, Mamoun Mohamed Ali Homeida. Demographic and Clinical Characteristics of Epilepsy in Childhood: A Prospective Cross Sectional Study from Sudan. International Journal of Central Nervous System Disease, 2021; 2:6. DOI: 10.28933/ijcnsd-2021-03-0505


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