A Rare Case of Adrenaline- Induced Kounis Syndrome presenting to the Emergency department

A Rare Case of Adrenaline- Induced Kounis Syndrome presenting to the Emergency department

Radhika Bulusu, Madhukiran Dontula, Indranil Das, VGR Shastry, Tamorish Kole

Institute of Emergency Medicine, VPS, Rockland Hospital, Manesar, Haryana

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Introduction: Kounis syndrome is the concurrent occurrence of acute coronary syndromes with hypersensitivity reactions [4] [3]. It has been established as a hypersensitivity coronary disorder induced by various conditions, drugs, environmental exposures, foods and coronary stents. Allergic, hypersensitivity, anaphylactic and anaphylactoid reactions are associated with this syndrome. Vasospastic allergic angina, allergic myocardial infarction and stent thrombosis with occluding thrombus infiltrated by eosinophils and/or mast cells. There are three principal variants of the syndrome: type 1 is allergy – related angina due to coronary spasm, whereas, type 2 is allergy related myocardial infarction due to plaque rupture or erosion and type 3 is allergy – related stent thrombosis with re – infraction.

Case summary: A young healthy male with no significant risk factors for coronary artery disease developed ventricular tachycardia and myocardial infarction following therapeutic dose of intramuscular administration of adrenaline for an anaphylactic reaction to the ED.

Keywords: Kounis Syndrome, Anaphylaxis, Adrenaline

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How to cite this article:
Radhika Bulusu, Madhukiran Dontula, Indranil Das, VGR Shastry, Tamorish Kole.A Rare Case of Adrenaline – Induced Kounis Syndrome presenting to the Emergency department. International Journal of Case Reports, 2017 3:34.


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