Biomedical Applications of Induced Pluripotent Stem Cells

Biomedical Applications of Induced Pluripotent Stem Cells

Neveen A. Salem

Biochemistry Department, Faculty of Science, University of Jeddah, Saudi Arabia
Narcotics, Ergogenic Aids and Poisons Department, Medical Research Division, National Research Centre, Egypt

International Journal of stem cell research

Induced pluripotent stem cells (iPSCs) which are efficiently produced from somatic cells by the introduction of four transcription factors (Oct4, Sox2, Klf4, and c-Myc) in fibroblasts could circumvent the restrictions of multipotent stem cells that obligated to differentiate into only several lineage cells and also, the ethical argument about ESCs that causes oocytes and embryo destruction . In addition, iPSCs are powerful tools applicable in biomedicine, cell therapy, pharmacology and toxicology. Therefore, the use of iPSCs in stem cell therapy has immense prospects and offer remarkable applications in regenerative medicine.This review aimed to summarize the most recent findings on iPSCs and focus on their biomedical applications.

Keywords: Biomedical Applications, Induced Pluripotent Stem Cells

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Neveen A. Biomedical Applications of Induced Pluripotent Stem Cells. International Journal of Stem Cell Research. 2019, 2:7 (This article has been withdrawn from International Journal of Stem Cell Research. Please do not use it for any purposes.)


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