International Journal of Hospital Pharmacy


Case report of west syndrome: a rare severe epilepsy in infants

Case Report of International Journal of Hospital Pharmacy Case report of west syndrome: a rare severe epilepsy in infants G. Pravalika1, Sushanta Kr Das1 and Saurabh Gupta2*  1Department of Pharm. D, CMR College of Pharmacy, Kandlakoya (V)-501 401, Hyderabad, India 2Department of Pharmacology, Indore Institute of Pharmacy, Rau pithumpur road-45331, Indore, Madhya Pradesh, India West syndrome (WS) also known as infantile spasms, is severe form of epilepsy of early childhood was first describe in 1840s. WS presents with myoclonic-tonic seizures (spasms) characterized by flexor, extensor or mixed movements with distinct electroencephalogram (EEG) pattern of hypsarrthmia and psychomotor arrest. Prevalence rate is ~ 4.0 cases per 10,000 children. Peak age of beginning is between 3 and 7 months; onset after 18 months is rare. Recent guidelines from the American Academy of Neurology and the Child Neurology Society for medical treatment of WS, recommends that ACTH is probably effective and vigabatrin is possibly effective in cessation of spasms of hypsarrhythmia. Although discovered 160 years ago, still its diagnosis, assessment and management continue to create many challenges to health care professionals and affected families. In this case of a 3 yr old male child was admitted for long period of almost 2 months before being discharged. This case was confirmed early but due to its complexity it took long time to get complete resolve of situation. ACTH with Valproate was found to effective; though ACTH showed some reactions still it was considered the best available medicine for WS. In conclusion, early detection and referral to a pediatric neurologist for clinical evaluation and prompt effective treatment is strongly recommended as it may improve prognosis ...


Editor-in-chief: 
Dr. Fadi Alkhateeb Professor

Vice Editor-in-Chief:
Dr. Saurabh Gupta Professor and Head

Editors

Dr. Mohammed A. Islam
Department of Pharmaceutical Sciences, West Coast University School of Pharmacy, Los Angeles, CA, USA.

Dr. Juseop Kang
Department of Pharmacology and Clinical Pharmacology Laboratory, College of Medicine, Hanyang University, Seoul 133-791, South Korea.

Dr. Mohamed Azmi Hassali
Professor of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.

Dr. Apollo James
Department of Pharmacy Practice, Nandha college of Pharmacy, Erode, Tamilnadu, India.

Dr. Iftikhar Ali
Department of Pharmacy, Northwest General Hospital and Research Center, Department of Pharmacy, University of Swabi, Khyber Pakhtunkhwa , Pakistan.

Dr Anthony David Hall
School of Clinical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.

Dr Bhanukumar M
Department of General Medicine, JSS Hospital & Medical College, JSS University, Mysore, India.

Dr. Sandeep Kumar Kar
Institute of Postgraduate Medical Education & Research, India.

Dr. Biswaranjan Paital
Department of Zoology, Orissa University of Agriculture and Technology, College of Basic Science and Humanities, Bhubaneswar-751003, Odisha, India.

Dr. Vasiliki E. Kalodimou
Director at Flow Cytometry-Research & Regenerative Medicine Department, Athens, Greece.

Dr. Hale Z. Toklu
Department of Pharmacology & Therapeutics, University of Florida College of Medicine, 32610 Gainesville, FL, USA.

Dr. Fahad Saleem
Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains, Malaysia, Minden 11800, Penang, Malaysia

Dr. Ahamada Safna Mariyam.M
Dept of Pharmacy Practice, Acharya & B.M Reddy College of Pharmacy, Bangalore-107, India.

Dr. Ghada Ismail El Shahat Ali Attia
Literature of Pharmacognosy, Departments of Pharmacognosy, Faculty of Pharmacy, TANTA University- Egypt

Dr. Tauqeer Hussain Mallhi
School Of Pharmaceutical Sciences, Usm, Penang, Malaysia

Dr. Burton M. Altura

Physiology and Pharmacology Department, SUNY Downstate Medical Center, NY, USA.

Dr.  Yousif Abdu Asiri
Vice – Rector for Planning and Development, Professor of Clinical Pharmacy, King Saud University,, Riyadh 11451, Saudi Arabia.

Dr. Amit K. Tiwari
Department of Pharmacology & Experimental Therapeutics, The University of Toledo – Health Science Campus, Toledo, OH, USA.

Dr. Saurabh Gupta
Professor and Head, Department of Pharmacology, Indore Institute of Pharmacy, Indore (M.P.), India, Principal Co-ordinator Scientist for outsources projects of industry, Indore institute of Pharmacy, Indore (M.P.), India, Scientist Co-ordinator member of Institutional Animal Ethical Committee, Indore institute of Pharmacy, Indore.

Dr. Tyler Madere
University of North Texas System College of Pharmacy –Department of Pharmacotherapy, Fort Worth, TX,USA.

Dr. Xianquan Zhan
Professor and Deputy Director, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China

Dr. Fatima Suleman
Head of Discipline of Pharmaceutical Sciences, School of Health Sciences, College of Health Sciences of University of KwaZulu-Natal, Durban, South Africa.

Dr. Mohamed Eddouks
Faculty of Sciences and Techniques Errachidia, Moulay Ismail University, Meknes, Morocco.

Dr.  Syed A. A. Rizvi 
Department of Pharmaceutical Sciences, College of Pharmacy, Health Professions Division, Nova Southeastern University, FL, USA.

Dr. Carmela Saturnino 
Faculty of Pharmacy, University of Salerno, SA, ITALY.

Dr. Taha Nazir
University of Sargodha, Sargodha 40100, Pakistan.

Dr. Fadi Alkhateeb
Pharmacy Administration, Department of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, Texas, USA.

Dr. Madhan Ramesh
Professor & Head, Department of Pharmacy Practice, JSS College of Pharmacy, JSS University, S S Nagar, Mysore.

Sushanta Kr. Das.
M. Pharm (Pharmacy Practice), Associate Professor and Pharm D Coordinator, CMR College of Pharmacy, Hyderabad

Dr. Mario Bernardo-Filho
Professor Titular, Universidade do Estado do Rio de Janeiro

Manuscript Title: The title should be a brief phrase.

Author Information: List full names and affiliation of all authors, including Emails and phone numbers of corresponding author.

Abstract: The abstract should be less than 500 words. Following abstract, a list of keywords and abbreviations should be added. The keywords should be no more than 10. Abbreviation are only used for non standard and long terms.

Introduction: The introduction should included a clear statement of current problems.

Materials and Methods: This section should be clearly described.

Results and discussion: Authors may put results and discussion into a single section or show them separately.

Acknowledgement: This section includes a brief acknowledgment of people, grant details, funds

References: References should be listed in a numbered citation order at the end of the manuscript. DOIs and links to referenced articles should be added if available. Abstracts and talks for conferences or papers not yet accepted should not be cited. Examples Published Papers: 

1.Kim P.G.M. Hurkens, Carlota Mestres-Gonzalvo, Hugo A.J.M. de Wit, Rob Janknegt, Frans Verhey, Jos M.G.A. Schols, Fabienne Magdelijns, Coen D.A. Stehouwer, Bjorn Winkens, Wubbo Mulder and P. Hugo M. van der Kuy. Assessing the strengths and weaknesses of a computer assisted medication review in hospitalized patients. International Journal of Hospital Pharmacy, 2017,2:6. DOI: 10.28933/IJHP-2017-10-0101 
2.Ananth kashyap, Rashmi N G, Rakshith U R, Hanumanthachar Joshi.Selective Serotonin Reuptake Inhibitors Induced Serotonin Syndrome –A Case Report. International Journal of Hospital Pharmacy, 2017,2:7. DOI:10.28933/ijhp-2017-10-1101

Tables and figures: Tables should be used at a minimum with a short descriptive title. The preferred file formats for Figures/Graphics are GIF, TIFF, JPEG or PowerPoint.

Proofreading and Publication: A proof will be sent to the corresponding author before publication. Authors should carefully read the proof to avoid any errors and return the proof to the editorial office. Editorial office will publish the article shortly and send a notice to authors with the links of the paper.

Open Access
International Journal of Hospital Pharmacy is a peer reviewed open access journal publishing research manuscripts, review articles, case reports, editorials, letters to the editor in Hospital Pharmacy (indexing details).

Peer Review
To ensure the quality of the publications, all submitted manuscripts will be peer-reviewed by invited experts in the field. The decisions of editors will be made based on the comments of the reviewers.

Rapid Publication
Time to first decision: within 2 days for initial decision without review, 18 days with review; Time to publication: Accepted articles will be published online within 2 days, and final corrected versions by authors will be accessible within 5 days. More details....

Rapid Response Team
Please feel free to contact our rapid response team if you have any questions. Our customer representative will answer you shortly.

International Journal of Hospital Pharmacy

Loading