International Journal of Neuroscience Research


Research Article of International Journal of Neuroscience Research Health Perceptions Between College Studentes From Pernambuco From Diferents Knowledge Areas Renata Alves de Sousa1*, Guilherme Brazão2, Péricles Bezerra de Freitas Júnior3, Everton Botelho Sougey4, Tatiana de Paula Santana da Silva5 1,2,4,5UFPE; 3FUNESO OBJECTIVE: to verify the association between general health perceptions with a focus on sleep quality, eating activities and concentration areas of the course after university admission. METHOD:  Cross-sectional study approved by ethics committee (n°2,581,563), with a sample of 432 undergraduate students from the Federal Public University, divided into three groups: Group 1: Humanities Students; Group 2: Health Students; Group 3: Exact Science students. For the collection, we used: vivências Acadêmicas’s questionnaire in the reduced version, and a sociodemographic questionnaire. Descriptive and inferential statistical techniques were used for analysis, considering a significance level of 5%. RESULTS: In the general sample, all general health perceptions were impaired after entering the University. In the analysis of the groups, it is noticed that Group 1 presented more negative rates of health perception (47.3% p (1) = 0.016), with significant and significant sleep-related impairments (68.2% p (1) = 0.002). On the other hand, the students in Group 3 presented the worst perceptions about the quality of food and difficulties in performing leisure activities (p (1) = 0.005). CONCLUSION: There was a significant association between university admission and negative health perceptions. In addition, it was found that the students in the humanities and exact areas were the most vulnerable.  Thus, it can be considered that academic experience can contribute negatively to the promotion of the health of young people, and, in this sense, it is recommended the implementation of educational programs aimed at self-care, prevention of academic stress and its negative effects on health. Keywords: Psychological Stress. Student Health. Mental Health ...


Review Article of International Journal of Neuroscience Research MOEBIUS SYNDROME AND ITS IMPLICATIONS FOR DENTAL TREATMENT Esdras Gomes da Silva1, Débora Correia de Oliveira1, Maria Ricarda Guilherme de Lemos Bacelar1, Rayane Pereira de Araújo1, Roberto Alcemar Alves de Sousa1, Mônica Soares de Albuquerque2 1Graduando do Curso de Odontologia da Universidade Federal de Pernambuco, Recife, Pernambuco, Brasil. 2Doutoranda de Dentística-Endodontia do Programa de Pós-Graduação em Odontologia da Faculdade de Odontologia da Universidade de Pernambuco/Departamento de Embriologia e Histologia Introduction: Moebius syndrome is a rare congenital neurological disease of unknown etiology, that involves several cranial nerves. The main clinical characteristic of this syndrome is the "mask-like face", that is, the absence of facial expression in situations of sorrow or joy. Objective: This study aims to describe the characteristics of Moebius syndrome and its main implications for dentistry. Methodology: In this study, a literature review was carried out, with searches in the following databases:, pubmed and medline. Furthermore, eight articles were selected, among which three were literature reviews and five were reports of clinical cases. Results: In addition to the genetic relation of the syndrome, there are factors that lead to this disorder, such as the use of misoprostol during pregnancy, for example. Conclusion: Early care for patients with Moebius syndrome by a multidisciplinary team is extremely important, since it will attenuate the effects of this pathology. Keywords: Moebius syndrome, Facial paralysis, Misoprostol, Cranial nerves paralysis ...


Research Article of International Journal of Neuroscience Research MORTALITY FOR ALZHEIMER'S DISEASE IN BRAZIL FROM 2010 TO 2017 Juliana Marina Campelo¹*, Jennifer Hellen Melo Sobral¹, Ana Clara De Andrade Pereira¹, Maria Anita Coelho Epaminondas¹, Aparecido Jonanthan Mandú de Araújo², Gysele Alexandre da Silva². 1Discente do Centro Universitário Maurício de Nassau – UNINASSAU, Recife, PE, Brasil. 2Discente da Universidade Federal de Pernambuco – Recife – PE, Brasil Introduction. The world population is aging and according to the World Health Organization (WHO), worldwide, the proportion of people aged 60 and over is growing rapidly, however, as life expectancy increases, neurodegenerative diseases and dementia may appear, such as Alzheimer's Disease (AD), a progressive and fatal disorder resulting from the death of hippocampal and cholinergic neurons that are responsible for the functions of memory, learning, emotional control, reasoning and behavior. These changes are characterized by loss of subcortical and cortical neurons, and marked atrophy of the local cerebral cortex where nerve cells in the brain control memory, reasoning, and judgment. Moreover, it is believed that this pathology has a multifactorial etiology, which can be determined by risk factors such as gender, age, environmental and genetic factors, low educational level and inflammatory reactions. Goal. To verify the prevalence of deaths in Brazil from Alzheimer's Disease in the period from 2010 to 2017. Method. A cross-sectional study was carried out by surveying the numbers of cases of death caused by Alzheimer's disease in the regions of Brazil from 2010 to 2017, available in the DATASUS / TABNET database, using the following variables for the research: region, gender, age group and ethnicity. Results. During the period from 2010 to 2017, a total of 121,232 numbers of cases of deaths from Alzheimer's Disease were recorded throughout Brazil. The Southeast region had a higher prevalence with 55.85% in relation to ...

The Effect of Nitrendipine and Levetiracetam in Pentylenetetrazole Kindled Rats

Research Article of International Journal of Neuroscience Research The Effect of Nitrendipine and Levetiracetam in Pentylenetetrazole Kindled Rats Meryem Dilek Karakurt1, Süleyman Emre Kocacan2, Cafer Marangoz3 1Ankara Yıldırım Beyazıt University Medical Faculty, Ankara, TURKEY 2Ondokuz Mayıs University Medical Faculty, Samsun, TURKEY 3Istanbul Medipol University Medical Faculty, Istanbul, TURKEY We aimed to investigate the efficacy of L-type voltage gated calcium channel blocker nitrendipine and levetiracetam in pentylenetetrazole (PTZ) kindled male rats. In order to establish kindling model, 35 mg/kg PTZ injected intraperitoneally (i.p.) to male wistar albino rats three days a week. Then, screw electrodes were placed in the skulls of the kindled rats. During the experiments, EEG activities and seizure behaviors of kindled rats were recorded. The kindled rats were divided into control (n=6), PTZ (n=6), nitrendipine (2.5 mg/kg (n=6), 5 mg/kg (n=6), 10 mg/kg (n=6)) and levetiracetam (10 mg/kg (n=6), 20 mg/kg (n=6), 40 mg/kg (n=6)) groups. Nitrendipine (5 mg/kg) and levetiracetam (20 mg/kg) were suppressed the spike frequency and the seizure score effectively (p<0.05). The effective doses of nitrendipine (5 mg/kg) and levetiracetam (20 mg/kg) were administered consecutively to the kindled animals (n=6). The co-administration of nitrendipine (5 mg/kg) and levetiracetam (20 mg/kg) did not effectively decrease the spike frequency and seizure score (p>0.05). The co-administration of nitrendipine and levetiracetam was not more effective than administration of nitrendipine or levetiracetam separately (p>0.05). Keywords: levetiracetam, nitrendipine, kindling model, voltage-gated calcium channels, rat ...

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