International Journal of Traditional and Complementary Medicine

Biogenic synthesis of Adhatoda vasica L. Nees mediated silver nanoparticles

Research Article of International Journal of Traditional and Complementary Medicine Biogenic synthesis of Adhatoda vasica L. Nees  mediated silver nanoparticles and their antibacterial, anticancer activity on Hep-G2 cell lines  Arumugam Sengottaiyan 1,*†, Chinnappan Sudhakar 1†, Kandasamy Selvam 2*, Thangaswamy Selvankumar 1, Muthusamy Govarthanan 1,3, Balakrishnan Senthikumar 2 and Koildhasan Manoharan 4 1 PG & Research Department of Biotechnology, Mahendra Arts and Science College (Autonomous), Kalippatti, Namakkal 637501, Tamil Nadu, India. 2 Centre for Biotechnology, Muthayammal College of Arts and Science, Rasipuram, Namakkal 637 408, Tamil Nadu, India 3 Division of Biotechnology, Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 570752, South Korea 4 Raja Duraisingam Government Arts & Science College, Sivagangai. †The first two authors equally contributed this work The present investigation has been studied with the green synthesis of silver nanoparticles (AgNPs) using medicinally valued Adhatoda vasica -Nees and to evaluate the antibacterial and anticancer activity against HEP-G2 (Human epithelium cells of liver cancer) cell lines. The UV-Vis spectroscopy results show a strong resonance centered on the surface of silver nanoparticles at 420 nm. Fourier transform infrared (FT-IR) spectroscopy study demonstrates A. vasica aqueous extract acted as the reducing and stabilizing agent during the synthesis. The X-ray diffraction (XRD) analysis confirmed that the synthesized AgNPs are single crystalline face-centered cubic in structure, average crystal size 21 nm. Scanning electron microscope–energy dispersive spectroscopy (SEM-EDS) image confirmed synthesis of relatively uniform nanoparticles. The EDS analysis of the nanoparticles dispersion, using a range of 2-4 keV, confirmed the presence of elemental silver, without any contamination. The antibacterial activities were carried out against pathogenic bacteria. The maximum zone of inhibition was observed in the synthesized AgNPs (10µg/mL) against Staphylococcus sp. (16mm), Klebsiella sp. (14.5mm). The cytotoxicity activity as evidence by MTT assay with HEP-G2 cell lines. The synthesized AgNPs are ready ...

Shilajatu for improvement in quality of life in patients of diabetes mellitus

Research Article of International Journal of Traditional and Complementary Medicine EVALUATION OF SHILAJATU FOR IMPROVEMENT IN QUALITY OF LIFE IN PATIENTS OF DIABETES MELLITUS Neha Lamba Ayurvedic Medical Officer, ESI Hospital, Jalandhar, Punjab As per WHO, in South-east Asia region alone 96 million people are estimated to be suffering from diabetes. Due to sedentary lifestyle and stress full nature of work, associated risk factors such as being overweight or obese, the number of diabetic patients is increasing. Diabetes is an important cause of blindness, kidney failure, lower limb amputation and other long-term consequences that impact on quality of life significantly. Continuous research is being done by scientists of various fields in order to achieve an effective cure of the disease and to improve quality of life. A great deal of work has also been done by Ayurvedic research scholars on various herbal and mineral drugs to find an effective treatment for diabetes generally reffered to as Prameha. Shilajatu is one such drug which has been described for the management of Prameha in Ayurveda texts. The present study was conducted to evaluate the efficacy of Shilajatu in the improving the quality of life in patients of Prameha. Twenty two diabetic patients were selected for the study. The results were assessed in terms of symptomatic relief on the basis of scoring system, as per the Questionnaire on Quality of Life. Statistically highly significant improvement (p <0.001) was observed on physical domain. Statistically significant improvement was observed on psychological domain with p<0.001. In terms of Social Relationships Domain also, highly significant improvement, with p <0.001 was observed. Highly significant improvement was observed in overall quality of life statistically with p <0.001. The study revealed that Shilajatu can be used as a drug in the management of Prameha to improve the quality of life of ...

Review on Sharngadhara Samhita

Review Article of International Journal of Traditional and Complementary Medicine Review on Sharngadhara Samhita Dr. Remya. A*, Dr. Divya Ravindran*, Dr. Aparna Sharma*, Dr. Anju Revi Kumar*, Dr. Abhaya kumar Mishra. M.D(Ayu), Ph.D**. *PG Scholars &**Associate Professor, Department of Rasashastra and Bhaishajya Kalpana, Amrita School of Ayurveda, Kollam, Kerala. Bhaishajya kalpana is a very well developed sub-discipline of Ayurveda entirely devoted to drug formulations. Sharangadhara Samhitha is an epitome of Ayurvedic literature of medieval India. Since the drug manufacturing part is elaborately dealt in this, it is considered as an authentic text book of Bhaishajya Kalpana. It is one pioneering work, aptly included in the list of Laghutrayi, the other two being Bhavaprakasha & Madhava nidana. Acharya Sharngadhara, son of Damodara is considered as the author of this text. Except giving out his name as the author at the commencement of the text, he has not furnished any information about himself or his other works. Sharngadhara Samhita composed of 3 parts or khandas in which 32 chapters and 2600 verses are explained. This book is designed in a simple and easy language to serve as a handbook and thus it shines in the pure hearts of Scholars and Practitioners. Keywords: Bhaishajya kalpana, Sharangadhara Samhitha ...

Bharat with its medicine

Review Article of International Journal of Traditional and Complementary Medicine Bharat with its medicine SHIVANI SANJEEV GAVANDE *Kayachikitsa department at Dr.J.J.Magdum Ayurved Medical College,Jaysingpur_Kolhapur,Maharashtra.416510 Bharat ,now known as India, by the world, is full of knowledge with advances since thousands of years. The nation has its own culture and healthy socio-economic life style since ancient time..This review article is concerned with its medical facilities that were available since ancient time in this continent. Ayurved is special boon to all the world by Bharat.Ayurved is not only the system of medicine but is a science of life…a direction to live healthy and long life. Keywords: Bharat,India,Ayurved,Hospitals,Tridosh ...


Dr. Papiya Bigoniya Professor, Radharaman College of pharmacy, Radharaman Group of Institutes, India.


Dr. Zhaoxiang Bian
Associate Vice-President, Chair Professor of School of Chinese Medicine, Director of Clinical Division and Associate Director of Institute of Creativity, Hong Kong Baptist University.

Dr. Woo-Sang Jung
Professor of Cardiology and Neurology (Stroke Center), College of Korean Medicine, Director of Korean Medical Emergency Room, Hospital of Korean Medicine, Kyung-Hee University.

Dr. M J Nanjan
Professor, Physical Chemistry (Retd.) of University of Madras, Chennai, India.

Dr. Daniel Man-yuen SZE
Deputy Program Coordinator for Master of Laboratory Medicine, School of Health & Biomedical Sciences and Health Innovations Research Institute (HIRi), RMIT University, Australia.

Dr. Shamim Ahmad
Professor of Microbiology, Officer In-Charge (Head) & Teacher In-Charge (Administrations), Microbiology Section, Institute of Ophthalmology, Faculty of Medicine , Aligarh Muslim University, India.

Dr. Qingwen Zhang
Associate Professor, Institute of Chinese Medical Sciences (ICMS), University of Macau.

Dr. Ansiur Rahman Khuda-Bukhsh
Former Head, Deptt. of Zoology, University of Kalyani, Presently an Emeritus Professor, University Grants Commission, Govt. of India, at  University of Kalyani.

Dr. Bajpayee Kaptain Kishor
Assistant Professor &HOD in the Botany Department, DR.RML P.G. COLLEGE (C.S.J.M. UNIVERSITY), HARDOI 241001 INDIA.

Dr. Hua-chuan Zheng
Professor, Cancer Research Center; Laboratory Animal Center; The Key Laboratory of Brain and Spinal Injury of Liaoning Province, Laboratory Animal Center, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China.

Dr. Emre Yalcinkaya
ESC Training Fellow in Electrophysiology, Clinic of Cardiology, University Hospital Zurich, Zurich, Switzerland.

Dr Zhi-Ling YU
Associate Professor, Teaching and Research Division, Fellow, Center for Cancer and Inflammation Research, Director, Master of Pharmaceutical Sciences in Chinese Medicine, Director, Consun Chinese Medicines Research Centre for Renal Diseases, Associate Director, Technology Development Division, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong

Dr. Mario Bernardo-Filho
Professor Titular, Universidade do Estado do Rio de Janeiro

Dr Shivani Sanjeev Gavande
Associate professor, Kayachikitsa at Dr. J.J.Magdum Ayurved medical college, Jaysingpur

Dr. Hiroyasu Satoh
Professor, Health Life Science, Shitennoji University, Habikino, Osaka 583-8501, Japan.

Dr. Paolo Roberti di Sarsina
Chairperson, Traditional Complementary and Alternative Medicine of the Observatory and Methods for Health, University of Milano-Bicocca, Milano, Italy.

Dr. Yibin Feng
Professor & Associate Director (Education), School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.

Dr. Afrozul Haq
Professor & Principal Scientist, R & D Division, VPS Healthcare, Abu Dhabi, United Arab Emirates (UAE).

Dr Manuel Fernandes Ferreira

Full Professor, Faculdade de Ciências da Universidade do Porto Rua do Campo Alegre, S/N Edifício FC4.Portugal.

Dr Jennifer Hunter
Senior Research Fellow, National Institute of Complementary Medicine, Western Sydney University, Australia.

Dr. Jiahong Lu
Assistant Professor, Institute of Chinese Medical Science, The University of Macau.

Dr. William Cho
Queen Elizabeth Hospital, Hong Kong.

Dr. Wenzhe Ma
Assistant Professor, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macau.

Dr Swapnil Sabgonda Patil
Assistant Professor, Dept. of Rognidan Avum Vikrutividnyan

Dr. Hongjie Zhang
Associate Professor, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong.

Dr. Nitin Mantri
Senior Lecturer in Biotechnology, Health Innovations Research Institute, School of Science, RMIT University, Victoria,  Australia.

Dr Dudhamal Tukaram Sambhaji
Assistant Professor, Dept. of Shalya Tantra, IPGT&RA,Gujarat Ayurveda University, Jamnagar, Gujarat, India.

Dr Thomas Harris
Complex Health Management, 85 Jubilee Av. Forest Lake. Q 4078. Australia.

Manuscript Title: The title should be a brief phrase.

Author Information: List full names and affiliation of all authors, including Emails and phone numbers of corresponding author.

Abstract: The abstract should be less than 500 words. Following abstract, a list of keywords and abbreviations should be added. The keywords should be no more than 10. Abbreviation are only used for non standard and long terms.

Introduction: The introduction should included a clear statement of current problems.

Materials and Methods: This section should be clearly described.

Results and discussion: Authors may put results and discussion into a single section or show them separately.

Acknowledgement: This section includes a brief acknowledgment of people, grant details, funds

References: References should be listed in a numbered citation order at the end of the manuscript. DOIs and links to referenced articles should be added if available. Abstracts and talks for conferences or papers not yet accepted should not be cited. Examples Published Papers: 

1. M. B. FALANA, M. O. BANKOLE and A. M. OMEMU. In Vivo effects of dosage of leaf, bark and root extracts of V. paradoxa on diarhoea-induced albino rats.International Journal of Traditional and Complementary Medicine 2018, 3:8. DOI: 10.28933/ijtcm-2018-07-0401 
2. Hemanth Kumar Manikyam, C.Ramesh, Krishna Mohan Poluri, Harinath Reddy Kasireddy, Charitha Devi Mekala.Bio-enhancement effect of Bos primigenius indicus urine isolates on Curcumin anticancer activity using different human cell line models of A549, Hep-G2, MCF-7, Jurkat and K562 .International Journal of Traditional and Complementary Medicine 2017, 2:2. DOI: 10.28933/ijtcm-2017-11-2001 

Tables and figures: Tables should be used at a minimum with a short descriptive title. The preferred file formats for Figures/Graphics are GIF, TIFF, JPEG or PowerPoint.

Proofreading and Publication: A proof will be sent to the corresponding author before publication. Authors should carefully read the proof to avoid any errors and return the proof to the editorial office. Editorial office will publish the article shortly and send a notice to authors with the links of the paper.

Open Access
International Journal of Traditional and Complementary Medicine is a peer reviewed open access journal publishing research manuscripts, review articles, case reports, editorials, letters to the editor in Traditional and Complementary Medicine (indexing details).

Peer Review
To ensure the quality of the publications, all submitted manuscripts will be peer-reviewed by invited experts in the field. The decisions of editors will be made based on the comments of the reviewers.

Rapid Publication
Time to first decision: within 2 days for initial decision without review, 18 days with review; Time to publication: Accepted articles will be published online within 2 days, and final corrected versions by authors will be accessible within 5 days. More details....

Rapid Response Team
Please feel free to contact our rapid response team if you have any questions. We will answer you shortly.

International Journal of Traditional and Complementary Medicine



Note: Please compress all documents (manuscript, cover letter et al.,. ) into one .Zip file and then upload the Zip file.