International Journal of Traditional and Complementary Medicine



Standardization and HPTLC, Fingerprinting study of Poly Herbal Formulation-Habb-e-Falij, traditionally used in the treatment of Paralysis and Facial Paisy treatment

Research Article of International Journal of Traditional and Complementary Medicine Standardization and HPTLC, Fingerprinting study of Poly Herbal Formulation-Habb-e-Falij, traditionally used in the treatment of Paralysis and Facial Paisy treatment Pawan Kumar Sagar*, R. Murugeswaran, M.W.Ahmed, Shahidul Khair,S.A.Ansari, Sonali Sajwan, S.A.A. Hashmi, Mohd Asif, Jitendra Kumar Drug Standardization Research Institute, (Under CCRUM, Ministry of AYUSH., Govt. of India), PLIM Campus, II nd Floor, Kamla Nehru Nagar, Ghaziabad, U.P., India Standardization is used to describe all measures under taken during the manufacturing process and quality control of drug assuring its reproducible quality. Most of the traditional medicines are effective but still they lack in their standard parameters. Therefore, we need to develop standard techniques to standardize and validate herbal formulations. The drug Habb-e-Falij is therapeutically useful in the treatment of Falij or Laqwa (Paralysis and Facial Paisy) and as a Nervine stimulant. The drug Habb-e-Falij was prepared in three different batches as per the guidelines of National Formulary of Unani Medicine (Part-I), Present study is aimed to evaluate the pharmacopoeial standards using physico-chemical parameters; HPTLC fingerprints, quality control and assurance parameters, using WHO guideline to ascertain the quality of drug. The physico-chemical data showed that the drug contain moisture(1.42%), total ash (75.0%), acid in-soluble (68.02%), alcohol and water soluble extractive matter (9.52%) and (11.47%), pH(1% solution) (5.30),pH(10% solution)(5.78) and the TLC / HPTLC finger prints showed various spots at 254nm, 366nm and visible light (V-S reagent). The quality control study revealed the absence of microbial load, aflatoxins, heavy metals and pesticide residues, The evaluated standards will be very much useful for laying the phamacopoeial standards of Habb-e-Falij and also in providing the quality medicine to needful human beings. Keywords: Habb-e-Falij, Physicochemical, Quality Control and Assurance parameters, TLC /HPTLC finger printing , Poly herbal formulation ...

Acute renal attack after treatment with Carapa Procera oil: two cases at the Ziguinchor Peace Hospital (Senegal West Africa) and review of the literature

Case Report of International Journal of Traditional and Complementary Medicine Acute renal attack after treatment with Carapa Procera oil: two cases at the Ziguinchor Peace Hospital (Senegal West Africa) and review of the literature KANE Yaya1*, SECK Sidy Mohamed3, BA AW Mamadou2, DIAWARA Mame Selly4, LEMRABOTT A T2,  FAYE Maria2, FAYE Moustapha2, CISSE M Moustapha4, KA El Fary2, NIANG Abdou2, DIOUF Boucar2 1Nephrology Hemodialysis Service, Peace Hospital Assane Seck University of Ziguinchor; 2HALD UCAD Dakar hemodialysis nephrology service;3St Louis UGB CHR hemodialysis nephrology service;4CHR hemodialysis nephrology department of Thiès / University of Thiès We describe two cases of impaired secondary renal function to a Carapa Procera taking as part of traditional treatment in Ziguinchor, southern Senegal. The certain or suspected toxicity of Carapa Procera is little known in the literature. In the two reported observations, no cause but the traditional treatment was found to explain the clinical picture presented. The development was favorable in all cases after medical treatment and a few hemodialysis sessions. we insist on the difficult context of investigation of these accidents, on the medical ignorance of these practices in sub-Saharan Africa and in Senegal in particular, as well as on the necessary collaboration with local botanists knowledgeable in traditional medicine. Keywords: Carapa procera, Kidney attack, Casamance ...

Regulatory Medicine In The Treatment Of Food Allergy

Case Report of International Journal of Traditional and Complementary Medicine Regulatory Medicine In The Treatment Of Food Allergy In Dog A Case Report Alena Micháľová DVM, Martina Takáčová DVM, Martina Karasová DVM, Assoc. Prof. Mária Fialkovičová DVM PhD. Department of Internal Diseases, Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Kosice, Slovakia Food allergy is defined as a pruritic dermatitis which is indicated by allergic reactions to food components. Due to its excessive incidence of clinical signs it is necessary to determine the correct diagnosis, provide sufficient control and long term management to achieve comfortable way of life for an animal. In case of very intensive pruritus there are usually used in common medicine glucocorticoids, antihistamincs and inhibitors of Janus kinase but there are also other alternatives such as bioresonance, homeopathy, phytotherapy, acupuncture, etc. that have also very beneficial and curative effect in case of food allergy. Diagnostics and therapy by bioresonance are alternative methods used in modern medicine that was discovered as a combination of quantum physics and Traditional Chinese Medicine. We can use it for various types of acute and chronic diseases without any invasive intervention into the body. There have been positive results in the diagnosis and treatment of allergies in dogs, which are nowadays constantly increased, and that have been one of the most common causes of dermatological and gastrointestinal diseases. Keywords: Food Allergy, Pruritus, Regulatory Medicine, Bioresonance, Homeopathy ...

Erythropoietic and hepatocurative profile of Yoyo Bitters® – A pilot study

Research Article of International Journal of Traditional and Complementary Medicine Erythropoietic and hepatocurative profile of Yoyo Bitters® - A pilot study Innocent U. Okagu1., Chinelo C. Nkwocha1., Adaeze Obi1., Nkiruka C. Ugochukwu1., Chukwudi Odo1., Christian C. Chibuogwu2*., Joseph C. Ndefo3., Victor N. Ogugua1., Sabinus I. Ofoefule2. and Benjamin C. Ozumba4 1Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria. 2Institute for Drug-Herbal Medicine-Excipient Research and Development, University of Nigeria, Nsukka, Enugu State, Nigeria.3Department of Science Laboratory Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.4Department of Obstetrics and Gynecology, College of Medicine, University of Nigeria, Enugu Campus. The present study evaluated the effects of a branded Nigerian polyherbal formulation, Yoyo® bitters on the haematological and biochemical status of hydrogen peroxide (H2O2)-intoxicated rats. Thirty (30) healthy male Wistar rats used in this study were divided into 6 groups of 5 rats each. Group 1 served as normal control and received 3 ml/kg body weight (b.w.). of distilled water only while group 2 served as experimental control and was intoxicated with H2O2 without treatment. Rats in groups 3-5 were H2O2-intoxicated and treated with 1, 2 and 3 ml/kg b.w. of Yoyo® bitters respectively while rats in group 6 were H2O2-intoxicated and treated 100 mg/kg. b.w. of silymarin. H2O2 was administered intraperitoneal on day 0 while drugs were orally administered from days 0 to 14. The rats were sacrificed on day 15 and blood samples collected were subjected to haematological and biochemical analyses. Intoxication with H2O2 significantly (p < 0.05) induced haematotoxicity, oxidative stress and hepatotoxicity when compared with control. Treatment of intoxicated rats with the formulation restored the haematological and biochemical status to normal, suggesting that Yoyo® bitters has erythropoietic and hepatocurative effects. However, future studies are required to confirm these effects in different in vivo models. Keywords: Yoyo® bitters, hepatocurative, haematology, ...

Editor-in-chief: 

Dr. Papiya Bigoniya Professor, Radharaman College of pharmacy, Radharaman Group of Institutes, India.

Editors:

Dr. Zhaoxiang Bian
Associate Vice-President, Chair Professor of School of Chinese Medicine, Director of Clinical Division and Associate Director of Institute of Creativity, Hong Kong Baptist University.

Dr. Woo-Sang Jung
Professor of Cardiology and Neurology (Stroke Center), College of Korean Medicine, Director of Korean Medical Emergency Room, Hospital of Korean Medicine, Kyung-Hee University.

Dr. M J Nanjan
Professor, Physical Chemistry (Retd.) of University of Madras, Chennai, India.

Dr. Daniel Man-yuen SZE
Deputy Program Coordinator for Master of Laboratory Medicine, School of Health & Biomedical Sciences and Health Innovations Research Institute (HIRi), RMIT University, Australia.

Dr. Shamim Ahmad
Professor of Microbiology, Officer In-Charge (Head) & Teacher In-Charge (Administrations), Microbiology Section, Institute of Ophthalmology, Faculty of Medicine , Aligarh Muslim University, India.

Dr. Qingwen Zhang
Associate Professor, Institute of Chinese Medical Sciences (ICMS), University of Macau.

Dr. Ansiur Rahman Khuda-Bukhsh
Former Head, Deptt. of Zoology, University of Kalyani, Presently an Emeritus Professor, University Grants Commission, Govt. of India, at  University of Kalyani.

Dr. Bajpayee Kaptain Kishor
Assistant Professor &HOD in the Botany Department, DR.RML P.G. COLLEGE (C.S.J.M. UNIVERSITY), HARDOI 241001 INDIA.

Dr. Hua-chuan Zheng
Professor, Cancer Research Center; Laboratory Animal Center; The Key Laboratory of Brain and Spinal Injury of Liaoning Province, Laboratory Animal Center, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China.

Dr. Emre Yalcinkaya
ESC Training Fellow in Electrophysiology, Clinic of Cardiology, University Hospital Zurich, Zurich, Switzerland.

Dr Zhi-Ling YU
Associate Professor, Teaching and Research Division, Fellow, Center for Cancer and Inflammation Research, Director, Master of Pharmaceutical Sciences in Chinese Medicine, Director, Consun Chinese Medicines Research Centre for Renal Diseases, Associate Director, Technology Development Division, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong

Dr. Mario Bernardo-Filho
Professor Titular, Universidade do Estado do Rio de Janeiro

Dr Shivani Sanjeev Gavande
Associate professor, Kayachikitsa at Dr. J.J.Magdum Ayurved medical college, Jaysingpur

Dr. Hiroyasu Satoh
Professor, Health Life Science, Shitennoji University, Habikino, Osaka 583-8501, Japan.

Dr. Paolo Roberti di Sarsina
Chairperson, Traditional Complementary and Alternative Medicine of the Observatory and Methods for Health, University of Milano-Bicocca, Milano, Italy.

Dr. Yibin Feng
Professor & Associate Director (Education), School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.

Dr. Afrozul Haq
Professor & Principal Scientist, R & D Division, VPS Healthcare, Abu Dhabi, United Arab Emirates (UAE).

Dr Manuel Fernandes Ferreira

Full Professor, Faculdade de Ciências da Universidade do Porto Rua do Campo Alegre, S/N Edifício FC4.Portugal.

Dr Jennifer Hunter
Senior Research Fellow, National Institute of Complementary Medicine, Western Sydney University, Australia.

Dr. Jiahong Lu
Assistant Professor, Institute of Chinese Medical Science, The University of Macau.

Dr. William Cho
Queen Elizabeth Hospital, Hong Kong.

Dr. Wenzhe Ma
Assistant Professor, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macau.

Dr Swapnil Sabgonda Patil
Assistant Professor, Dept. of Rognidan Avum Vikrutividnyan

Dr. Hongjie Zhang
Associate Professor, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong.

Dr. Nitin Mantri
Senior Lecturer in Biotechnology, Health Innovations Research Institute, School of Science, RMIT University, Victoria,  Australia.

Dr Dudhamal Tukaram Sambhaji
Assistant Professor, Dept. of Shalya Tantra, IPGT&RA,Gujarat Ayurveda University, Jamnagar, Gujarat, India.

Dr Thomas Harris
Complex Health Management, 85 Jubilee Av. Forest Lake. Q 4078. Australia.

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1. M. B. FALANA, M. O. BANKOLE and A. M. OMEMU. In Vivo effects of dosage of leaf, bark and root extracts of V. paradoxa on diarhoea-induced albino rats.International Journal of Traditional and Complementary Medicine 2018, 3:8. DOI: 10.28933/ijtcm-2018-07-0401 
2. Hemanth Kumar Manikyam, C.Ramesh, Krishna Mohan Poluri, Harinath Reddy Kasireddy, Charitha Devi Mekala.Bio-enhancement effect of Bos primigenius indicus urine isolates on Curcumin anticancer activity using different human cell line models of A549, Hep-G2, MCF-7, Jurkat and K562 .International Journal of Traditional and Complementary Medicine 2017, 2:2. DOI: 10.28933/ijtcm-2017-11-2001 

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