International Research Journal of Public Health


Extraordinary Rapid Wound Healing Time in Diabetic Patients Treated with Microburst Insulin Infusion

Research Article of International Research Journal of Public Health Extraordinary Rapid Wound Healing Time in Diabetic patients treated with Microburst Insulin Infusion John P. Elliott, M.D.1 ,Andrew Elliott, BS1 Allison Cimler, NP-C1 Nardo Zaias, M.D.2 Sandra Escovar, M.D.2 1Diabetic Innovations, Scottsdale, AZ; 2Trina Health of Florida, Miami FL; 3Trina Health, Sacramento, CA Importance: Non-healing diabetic ulcerations of the foot lead to amputations and premature mortality.  Microburst Insulin Infusion has demonstrated an ability to accelerate healing in otherwise non-healing wounds. Objective:  To demonstrate the benefit of adding Microburst Insulin Infusion to conventional diabetic wound care to significantly decrease wound healing time. Methods:  A case series of five patients received Microburst Insulin Infusion therapy for significant peripheral diabetic ulcerations after failing conventional wound care.  These five cases were treated from 4 independent Microburst Insulin Infusion clinics.  Four of the wounds exceeded 6 cm².  Patient charts were reviewed and relevant data was collected. All individuals in this manuscript have given written informed consent to publish these case details. Setting: Multicenter referral clinics providing Microburst Insulin Infusion Therapy Exposure: Microburst Insulin Infusion is an adjunctive treatment to conventional diabetic therapy performed in an outpatient clinic setting.  A weight based oral glucose dose is administered while pulsatile intravenous insulin is delivered by the Bionica Microdose pump.  The treatment is comprised of three 1 hour sessions and occurs up to five times a week, when the patient presents with un-healing wounds. Main Outcomes and Measures: Time to wound healing. A secondary outcome was failure of wound healing. Hypothesis for this study was formulated post treatment. Results: A significant decrease in wound healing time was observed when utilizing Microburst Insulin Infusion.  The mean time to complete healing was 84.2 days compared to 133 days in published literature(1).  The patient with a foot wound measuring an amazing 228.6 cm² ...

Heavy Metals and Trace Elements in Blood, Hair and Urine of Nigerian Children with Autistic Spectrum Disorder

Research Article of International Research Journal of Public Health Heavy Metals and Trace Elements in Blood, Hair and Urine of Nigerian Children with Autistic Spectrum Disorder Blaurock-Busch E. PhD1 and Nwokolo Chijioke C.2 1Research Scientist, Lecturer, Micro Trace Minerals Laboratory, Germany. Advisor, German Medical Association of Clinical Metal Toxicology; Address: Röhrenstr. 20, 91217 Hersbruck, Germany; 2University of Benin, Dept. of Biochemistry Faculty of Life Sciences, Benin City, Nigeria Autism spectrum disorders (ASD) are a group of developmental disorders defined by a range of behavioral problems including social withdrawal, communication deficits, and stereotypic/repetitive behavior. Patient observation and clinical history rather than biomarkers as known in laboratory analysis are the defining factors. Pathophysiological etiologies remain controversial, but genetic and environmental factors have been discussed in recent years. International research has focused on neurotoxic metals such as mercury and lead, suggesting that these and other metals contribute to the development of the disorder. Since the Niger-Delta region of Nigeria is widely known for its petroleum industry and pollution, we aimed to evaluate if Nigerian children diagnosed with ASD carry a greater burden of toxic metals compared to healthy Nigerian children living in the same region. While the ASD group shows a higher metal concentration in blood and hair, combined with low blood zinc levels, we also determined an unusual metal burden in the healthy group but no zinc deficiency. Keywords:Autism, Toxic Metal Burden, Zinc, Niger Delta ...

The influence of population aging in Public Health

Review Article of International Research Journal of Public Health The influence of population aging in Public Health Nélio Veiga 1,2, Patrícia Couto 1,2, Adélia Fernandes 1, Alexia Oliveira 1, Daniela Gomes 1, Daniela Santos 1, Odete Amaral 3, Carlos Pereira 3, Pedro Pereira 1, Inês Coelho 4 1Health Sciences Institute, Universidade Católica Portuguesa-Viseu, Portugal; 2Centre for Interdisciplinary Health Research (CIIS)- Universidade Católica Portuguesa, Portugal; 3CI&DETS- Polytechnic Institute of Viseu, Portugal; 4Family Health Unit Grão Vasco- Viseu, Portugal. Introduction Population aging is one of the greatest challenges in contemporary public health. Thus, one of the consequences of this dynamic is a greater demand for health services. The aim of the present research consists in explaining the main topics that justify the fact that the increase of population-aging worldwide influences public health strategies applied. Materials and methods To carry out this review article the search strategies included electronic databases, such as PubMed, Cochrane Library and Science Direct, reference lists of articles, and selected textbooks. Articles and textbooks used in this study were mainly reached by using the following keywords: "Public health"; "Population-ageing "; "Global Aging"; "Elderly" and "Health". Selection criteria included articles published from 1985 to the present year of 2018. At the end of the search, 11 scientific articles were selected. Results and Discussion The physical / biological, psychological and social changes associated with the elderly leads to decrease of health, withdrawal from the labor market and several unfavorable situations, which cannot be controlled. In this context, the elderly seek to find support in the family, neighborhood, friends and institutions that will influence their quality of life. Therefore, the path of Public Health has three essential points: first, health promotion and primary prevention, which requires a lot of health education to develop healthy living habits and improve understanding of the aging ...

2016 Deterministic Model Behind Zika Virus Infections in Brazil

Research Article of International Research Journal of Public Health 2016 Deterministic Model Behind Zika Virus Infections in Brazil Isack E. Kibona, Cuihong Yang, Shanshan Dong College of Mathematics and Statistics, Central China Normal University, 152 Luoyu Avenue, Wuhan, Hubei 430079, P. R. China We formulated a deterministic model for simulation of zika virus (ZIKV) infections. This cooperates with WHO serious alert on February 1st, 2016 to contain ZIKV epidemic in the world, Brazil being the most hit. Accordingly, we have taken Brazil records on ZIKV cases as an example to justify the model. According to the model, simulations suggests that by 2020, ZIKV infections is no longer a threat in this country. In our analytic analysis we have included some brief simulations as specific cases. Finally, model simulation is all about Brazil. In this model, besides a disease free equilibrium (DFE) point being globally stable, analysis of local DFE has two sets of eigenvalues, leading two different qualitative behavior. This follows due to variation in some parameters. In each of these two sets, none has backward bifurcation. That is the disease is controllable when R_0<1. Otherwise, when R_0>1 the disease free is unstable. In the analytic analysis of either qualitative behavior, we have associated brief simulation. Only analytic analysis of endemic equilibrium has not been fully developed. We have considered Brazil ZIKV cases from January 2016 onward to verify the model plus having some predictions about ZIKV infections to around 2020. The basic reproduction (R_0) has been estimated as R_0=0.1922<1, since then ZIKV infections has been decreasing since highest peak in early 2016. Should this value of R_0=0.1922 be stabilized or lowered, then ZIKV infections is no longer a threat in Brazil by 2020. Simulations for Brazil has been extended to understand the possible situation if R_0>1. Keywords:Deterministic model of ...

Dr. Mohammad Hadi Dehghani
Professor, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences

Dr. Beatrice O. Ondondo 
Department of Biomedical Sciences, School of Health Sciences, Cardiff Metropolitan University, Llandaff Campus, Western Avenue, Cardiff, CF5 2YB

Ms. Yau Sui Yu
Assistant Professor (Nursing), The Open University of Hong Kong C0924, The Open University of Hong Kong, 30, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong

Dr. Mario Bernardo-Filho
Professor Titular, Universidade do Estado do Rio de Janeiro

Dr Anirudh V. Mutalik
Assistant Professor and Incharge Rural Health Training Centre. KMCT Medical College,Calicut

Dr. Hamdy Ahmad Sliem
Professor, Internal Medicine, Faculty of medicine, Suez Canal University, Egypt

Dr. Abdelrahman Y. Fouda
Vascular Biology Center, R.B. Caldwell lab, Augusta University

Dr. Kabita Mishra
Senior Research Fellow (Homoeopathy), D.D.P.R.-Central Research Institute for Homoeopathy , (Ministry of A.Y.U.S.H., Government of India)

Dr. Ionel BONDOC
Associate Professor, University of Agricultural Sciences and Veterinary Medicine Iasi, Faculty of Veterinary Medicine Iasi (ROMANIA), Department of Public Health

Dr Col Narendra Singh
Professor Community Medicine, Central Govt Medical College & Hospital in Faridabad , India

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1. John P. Elliott, Andrew Elliott, Allison Cimler,Nardo Zaias, Sandra Escovar. Extraordinary Rapid Wound Healing Time in Diabetic Patients Treated with Microburst Insulin Infusion.International Research Journal of Public Health, 2018; 2:14. DOI:10.28933/irjph-2018-08-1001 
2. Blaurock-Busch E. and Nwokolo Chijioke C. Heavy Metals and Trace Elements in Blood, Hair and Urine of Nigerian Children with Autistic Spectrum Disorder. International Research Journal of Public Health, 2018; 2:13. DOI:10.28933/irjph-2018-07-2201

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