Review Article of Journal of Herbal Medicine Research
Medicinal Plants Used for the Management of Asthma in Ethiopia – A Review
Bihonegn Sisay1*, Asfaw Meresa1, Eyob Debebe1, Worku Gemechu1, Tsion kasahun1, Frehiwet Teka1 , Tigist Abera1, Sameson Taye1
Traditional and Modern Medicine Research Directorate, Ethiopian Public Health Institute, Addis Ababa Ethiopia
INTRODUCTION: Asthma is one of the most common chronic diseases in contemporary society and there is increasing evidence to suggest that its incidence and severity are increasing. Medicinal plants, also called medicinal herbs, have been discovered and used in Traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for functions including protection against insects, fungi, diseases, and herbivorous mammals etc. Further, the phytochemical content and pharmacological actions, if any, of many plants having medicinal potential remain unassisted by exact scientific research to define efficacy and safety. OBJECTIVE: The aim of this review is to give an on the way into some of the most commonly used medicinal plants, phytochemical information of plants and their method of preparation for the management of asthma. METHOD: In these review assembly information of the medicinal plants used to management of asthma from publication journals, thesis, literature searching. In addition to these some of literature qualitative and quantities determination of the phytochemical screen and bioactivity. RESULT: In the review a total of 23 medicinal plants collect from different literature. This finding is a good indicator for the presence of considerable diversity of plant species for the management of Asthma. The most common medicinal plants that used in the society are Papilionaceae, Caricaceae, Moringaceae, Liliaceae, Asteraceae etc. The society used all parts of medicinal plants like stem, root, bark, leafs, fruit, flowers, seed etc. CONCLUSION: In these review a good number of contemporary medicines have evolved from traditional medicines thus in the present circumstances, our traditional system must be given an objective and critical examination. Further research must be carried out to determine the fraction(s)/compounds that are mostly responsible for the observed anti-asthmatic activity as this will lead to drug development. As well, the potency of plants used in combination as beside being used individually should be further researched on. It is recommended that further research is needed to anti-asthmatic plants and standardization of herbal formulations/preparations and to determine the medicinal plants side effect, efficacy, safety etc.
Keywords: asthma, medicinal plants, ethno-botanical, herbal, phytochemistry
How to cite this article:
Bihonegn Sisay, Asfaw Meresa, Eyob Debebe, Worku Gemechu, Tsion kasahun, Frehiwet Teka, Tigist Abera1, Sameson Taye. Medicinal Plants Used for the Management of Asthma in Ethiopia – A Review. Journal of Herbal Medicine Research, 2019,4:35. (This article has been retracted from Journal of Herbal Medicine Research per the request of authors. Please do not use it for any purposes. )
1.Choudhry, S., Seibold, M. A., Borrell, L. N., Tang, H., Serebrisky, D., Chapela, R. … & Risch, N. J. (2007). Dissecting complex diseases in complex populations: asthma in Latino Americans. Proceedings of the American Thoracic Society, 4(3), 226-233.).
2. Taur, D. J., & Patil, R. Y. (2011). Some medicinal plants with antiasthmatic potential: a current status. Asian Pacific journal of tropical biomedicine, 1(5), 413-418.)).
3. Rosenberg, Reena, et al. “An unusually high prevalence of asthma in Ethiopian immigrants to Israel.” FAMILY MEDICINE-KANSAS CITY- 31 (1999): 276-279.
4. Ober, C., & Hoffjan, S. (2006). Asthma genetics 2006: the long and winding road to gene discovery. Genes and immunity, 7(2), 95.)
5. Panthong, A., Kanjanapothi, D., & Taylor, W. C. (1986). Ethno botanical review of medicinal plants from Thai traditional books, Part I: Plants with anti-inflammatory, anti-asthmatic and antihypertensive properties. Journal of Ethno pharmacology, 18(3), 213-228.).
6. Jayaprakasam, B., Yang, N., Wen, M. C., Wang, R., Goldfarb, J., Sampson, H., & Li, X. M. (2013). Constituents of the anti-asthma herbal formula ASHMI™ synergistically inhibit IL-4 and IL-5 secretion by murine Th2 memory cells, and eotaxin by human lung fibroblasts in vitro. Journal of integrative medicine, 11(3), 195-205.)
7. Teotia, U. V. S., Mishra, A. K., Kumar, R., & Deepa, V. K. (2014). Antiasthmatic potential of some medicinal plants, Asian Pac. J. Health Sci, 1(3), 155-161.
8. Prasad, Ranjeeta, Rahul Dev Lawania, and Rajiv Gupta. “Role of herbs in the management of asthma.” Pharmacognosy Reviews 3.6 (2009): 247.
9. Kumar, S., Agnihotri, V. K., Thakur, S., Verma, A., Saxena, R. C., & Soni, K. K. (2012). Some important medicinal plants used in the treatment of asthma-a review. Int. J. Pharma. Sci. Res, 3(10), 500-502.)
10. (Clarke, R., Lundy, F. T., & McGarvey, L. (2015). Herbal treatment in asthma and COPD–current evidence. Clinical Phytoscience, 1(1), 4.)
11. Shenoy, C., Patil, M. B., Kumar, R., & Patil, S. (2009). Preliminary phytochemical investigation wound healing activity of Allium cepa Linn (Liliaceae). International Journal of Pharmacy and Pharmaceutical Sciences, 2(2), 167-175.
12. Pareek, Sunil, et al. “Onion (Allium cepa L.).” Fruit and Vegetable Phytochemicals: Chemistry and Human Health, 2nd ed.; Yahia, EM, Ed (2017): 1145-1161.
13. Tesfaye, A., & Mangesha, W. (2015). Traditional Uses, Phytochemistry and Pharmacological Properties of Garlic (Allium Sativum) and its Biological Active Compounds. International Journal of Scientific Research, Engineering and Technology, 1(5), 142-148.).
Vijayanand, S., & Sanjana, T. (2017). Phytochemical Studies of Phyllanthus emblica, Ananas comosus, Momordica charantia Extracts. Int J Pharma Res Health Sci, 5(4), 1810-15.).
14. Biu, A. A., Buratai, L. B., Ahmed, A. A., Hambali, I. U., Ngulde, S. I., Zakariah, M., & Lawal, J. R. (2016). phytochemistry, toxicity and efficacy of crude aqueous extract of carica papaya leaf against trypanosoma brucei. Bangladesh Journal of Veterinary Medicine, 14(1), 99-102.
15. Street, R. A., Sidana, J., & Prinsloo, G. (2013). Cichorium intybus: Traditional uses, phytochemistry, pharmacology, and toxicology. Evidence-Based Complementary and Alternative Medicine, 2013.
16. Ekpenyong, C. E., Akpan, E. E., & Daniel, N. E. (2014). Phytochemical Constituents, Therapeutic Applications and Toxicological Profile of Cymbopogon citratus Stapf (DC) Leaf Extract. Journal of Pharmacognosy and Phytochemistry, 3(1).).
17. Ahmad, W., Singh, S., & Kumar, S. (2017). Phytochemical screening and antimicrobial study of Euphorbia hirta extracts. J Med Plants Stud, 5, 183-186.
18. Ololade, Z. S., Kuyooro, S. E., Ogunmola, O. O., & Abiona, O. O. (2017). Phytochemical, Antioxidant, Anti-Arthritic, Anti-Inflammatory and Bactericidal Potentials of the Leaf Extract of Lactuca teraxacifolia. Global Journal of Medical Research.
19. Patel, P., Patel, N., Patel, D., Desai, S. H. A. R. A. V., & Meshram, D. (2014). Phytochemical analysis and antifungal activity of Moringa oleifera. International Journal of Pharmacy and Pharmaceutical Sciences, 6(5), 144-147.
20. Yessuf, A. M. (2015). Phytochemical extraction and screening of bio active compounds from black cumin (Nigella Sativa) seeds extract. Am J Life Sci, 3, 358-364.
21. Boskabady, Mohammad Hossein, et al. “The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients.” Fundamental & clinical pharmacology 21.5 (2007): 559-566
22. Mega, T. P., Santos, P. D. M., Souza-Machado, A., Noblat, L. D. A. B. C., & Cruz, Á. A. (2011). Use of medicinal herbs by patients with severe asthma managed at a Referral Center. Brazilian Journal of Pharmaceutical Sciences, 47(3), 643-649.
23. Madike, L. N., Takaidza, S., & Pillay, M. (2017). Preliminary phytochemical screening of crude extracts from the leaves, stems, and roots of Tulbaghia violacea. Int J Pharmacogn Phytochem Res, 9(10), 1300-1308.
24. Okoli, R. I., Aigbe, O., Ohaju-Obodo, J. O., & Mensah, J. K. (2007). Medicinal herbs used for managing some common ailments among Esan people of Edo State, Nigeria. Pakistan Journal of Nutrition, 6(5), 490-496.
25. Getaneh, S., & Girma, Z. (2014). An ethno botanical study of medicinal plants in Debre Libanos Wereda, Central Ethiopia. African Journal of Plant Science, 8(7), 366-379.
26. d’Avigdor, E., Wohlmuth, H., Asfaw, Z., & Awas, T. (2014). The current status of knowledge of herbal medicine and medicinal plants in Fiche, Ethiopia. Journal of Ethno biology and Ethno medicine, 10(1), 38.
27. Sonibare, M. A., and Z. O. Gbile. “Ethno botanical survey of anti-asthmatic plants in South Western Nigeria.” African Journal of Traditional, Complementary and Alternative Medicines 5.4 (2008): 340-345.
28. Gebeyehu, G. (2016). An ethno botanical study of traditional use of medicinal plants and their conservation status in Mecha Wereda, West Gojam Zone of Amhara Region, Ethiopia. MScThesis; 2011.
29. Regassa, R. (2013). Assessment of indigenous knowledge of medicinal plant practice and mode of service delivery in Hawassa city, southern Ethiopia. Journal of Medicinal Plants Research, 7(9), 517-535.
30. Kassa, Zewdie, Zemede Asfaw, and Sebsebe Demissew. “Ethno botanical study of medicinal plants used by the local people in Tulu Korma and its surrounding areas of Ejere district, Western Shewa zone of Oromia regional state, Ethiopia.” Journal of Medicinal Plants Studies 4.2 (2016): 24-47.
31. Qureshi, R. A., Ghufran, M. A., Sultana, K. N., Ashraf, M., & Khan, A. G. (2007). Ethnomedicinal studies of medicinal plants of Gilgit District and surrounding areas. Ethnobotany Research and Applications, 5, 115-122.
32. Birhanu, Z., Endale, A., & Shewamene, Z. (2015). An ethno medicinal investigation of plants used by traditional healers of Gondar town, North-Western Ethiopia. Journal of medicinal plants studies, 3(2), 36-43.
33. Regassa, R., Bekele, T., & Megersa, M. (2017). Ethno botanical study of traditional medicinal plants used to treat human ailments by Halaba people, southern Ethiopia. Journal of Medicinal Plants Studies, 5(4), 36-47.
34. Panthong, A., Kanjanapothi, D., & Taylor, W. C. (1986). Ethno botanical review of medicinal plants from Thai traditional books, Part I: Plants with anti-inflammatory, anti-asthmatic and antihypertensive properties. Journal of Ethno pharmacology, 18(3), 213-228.
35. (Prasad, R., Lawania, R. D., & Gupta, R. (2009). Role of herbs in the management of asthma. Pharmacognosy Reviews, 3(6), 247.)
36. Ismail, M. Y. M. (2010). Antiasthmatic herbal drugs-a review. International Journal of Pharmacy and Pharmaceutical Sciences, 2(3), 28-29.