Journal of Herbal Medicine Research


Evaluation of antimicrobial efficacy of ethanolic extract of Panax ginseng against Periodontal pathogens: An invitro study

Research Article of Journal of Herbal Medicine Research Evaluation of antimicrobial efficacy of ethanolic extract of Panax ginseng against Periodontal pathogens: An invitro study 1Amulya. K.S., 2Jayasheela M., 3Gayathri G., 4Mehta D.S. 1Post graduate student, Department of Periodontics, Bapuji dental college and hospital, Davangere, Karnataka, India; 2Professor, Department of Periodontics, Bapuji dental college and hospital, Davangere, Karnataka, India; 3Professor, Head of the department, Department of Periodontics, Bapuji dental college and hospital, Davangere, Karnataka, India; 4Professor, Department of Periodontics, Bapuji dental college and hospital, Davangere, Karnataka, India The present experimental study was carried out with the aim of evaluating the antibacterial activity of ethanolic extract of Panax ginseng on the most common periodontal pathogens, Porphyromonas gingivalis (Pg) Prevotella intermedia (Pi), Fusobacterium nucleatum (Fn) and Aggregatibacter actinomycetemcomitans (Aa). Ethanolic extract of Panax ginseng was prepared using maceration technique. Thus obtained extract was tested for its antimicrobial efficacy against 4 periodontal pathogens by means of evaluating the Minimum inhibitory concentration (MIC), Minimum bactericidal concentration (MBC) and time kill curve analysis. MIC was carried out by using serial dilution method. MBC was assessed by incubating the cultures of microorganisms with the same drug concentrations as MIC. Time kill curve (TKC) was analysed by incubating the organisms in anaerobic chamber, to evaluate the timely declination of growth rate. The results indicated that the ethanolic extract of Panax ginseng was both bacteriostatic and bactericidal for Pg and Pi at 0.8 µg/ml and for Fn at 50 µg/ml. But for Aa, it was only bacteriostatic at 25 µg/ml but not bactericidal in nature. Also, Pg showed no growth after 10 minutes, but the growth of Pi, Fn and Aa was not inhibited even after incubation for 2 hours. From this in-vitro study we conclude that the ethanolic extract of panax ginseng showed antimicrobial efficacy against all the ...

Validation of Ewé’fá as Herbal Recipes for Reproductive Health Problems (RHPs) among the Yorùbá of South-western Nigeria

Research Article of Journal of Herbal Medicine Research Validation of Ewé’fá as Herbal Recipes for Reproductive Health Problems (RHPs) among the Yorùbá of South-western Nigeria Aderemi S. Ajala1*, Mubo A. Sonibare2, Idayat T. Gbadamosi3, S. K. Olaleye4, Oluwatoyin Odeku5, Aremu O. Adegoke6, A. G. Adejumo7, 1Department of Archaeology and Anthropology, University of Ibadan, Ibadan, Nigeria; 2Department of Pharmacognosy, University of Ibadan, Ibadan, Nigeria; 3Department of Botany, University of Ibadan, Ibadan, Nigeria; 4Department of Religious Studies, University of Ibadan, Ibadan, Nigeria; 5Department of Pharmaceutics and Industrial Pharmacy, University of Ibadan, Ibadan, Nigeria; 6Department of Pharmaceutical Chemistry, University of Ibadan, Ibadan, Nigeria; 7Department of African Languages and Linguistics, University of Ibadan, Ibadan, Nigeria Ifá scriptural verses contain a number of herbs for healing different ailments among the Yorùbá of Nigeria. Thus, Ifá is one of the epistemologies of Yorùbá herbal healing system. Considering religious sentiments and secrecy arising from patenting, hermeneutic analysis and validation of Ifá-based herbs (Ewé’fá) is yet to be scientifically engaged. This paper analyses some Ifá verses and identifies Ewe’ fa mentioned in them for validation, focussing reproductive health problems (RHPs). Thirty medicinal plants mentioned in six selected Ifá verses (Èjìogbè, Ògúndábède, Òyèkú-Méjì, Ogbè- Túrúpòn, Ìwòrì- Òfún, and Òtúrá-Méjì) for the treatment and management of RHPs were identified. Ethnographic and ethno-botanical surveys of those herbs were conducted in Bode herbs market in Ibadan, Nigeria. Key informants’ interviews, observation, and semi-structured ethno-botanical questionnaire were used. Interviews focused on sources of Ewé’fá and mode of treatment in RHPs, botanical information on Ewé’fá, knowledge value of identified Ewé’fá, and uses and validation of Ewé’fá in the treatment of RHPs. Nineteen respondents, mainly herb sellers (78.9%) and some traditional medical practitioners (21.1%) were involved in the survey. All the respondents were females, aged 41-60 years (52.6%) and 78.9% of them were Muslims. Herbal ...

Neurophysiological effects of a special extract of Cyperus esculentus L. (Cyperol)

Research Article of Journal of Herbal Medicine Research Neurophysiological effects of a special extract of Cyperus esculentus L. (Cyperol) Wiebe JC., López-Ríos L., Vega-Morales T., Pérez-Machín R., Mateos CJ., Gericke N. Nektium Pharma, Agüimes, Spain. The tuberous rhizomes of Cyperus esculentus L. have been used as a food by hunter-gatherer and agricultural societies for millennia. Varieties and selections of the plant are cultivated in southern Europe, north Africa and west Africa. There is popular food and beverage uses, and traditional medicinal uses suggest that the “tubers” may have functional food potential. The first standardized extract of Cyperus esculentus, Cyperol, has been developed and commercialized. In order to characterize the central nervous system activity of this extract a series of neurophysiological studies were undertaken in-vitro, in-vivo and in a pilot clinical study. The results of the studies indicate that Cyperol induces changes in brain electrical activity (EEG), demonstrating that bioactive compounds from the extract are absorbed, are bioavailable, and that these compounds or their metabolites cross the blood brain barrier. Taken overall, the results of the reported studies indicate calming activity without sedation. This extract does indeed have functional food potential and could be used to maintain a calm state of mind while dealing with cognitively demanding work. Preliminary indications suggest that the extract may have anxiolytic potential which should be explored in future clinical studies. Keywords: Cyperus esculentus, Cyperol, stress, calm, anxiolytic, non-sedating ...

Current Situation, Problems and Countermeasures of Poverty Alleviation in Traditional Chinese Medicine industry

Review Article of Journal of Herbal Medicine Research Current Situation, Problems and Countermeasures of Poverty Alleviation in Traditional Chinese Medicine industry Min Xu Hainan radio and television university, Address: No. 20, haidian erxi road, haikou city, hainan province, zip code: 570208. Poverty alleviation by industry plays an indispensable role in poverty alleviation, and poverty alleviation by Chinese medicine industry, as one of the industrial development models with local characteristics in recent years, has achieved remarkable results. However, there are also some problems that cannot be ignored. It is of great practical significance to analyze and put forward countermeasures for the healthy development of poverty alleviation industries, promote economic growth in poor areas, increase income of poor households and realize the building of a moderately prosperous society in all respects. Keywords: Traditional Chinese Medicine; Industry for poverty alleviation; Countermeasures ...

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