Journal of Herbal Medicine Research


The Basic Nature and analysis of Ganoderma Lucidum

Review Article of Journal of Herbal Medicine Research The Basic Nature and analysis of Ganoderma Lucidum Guan Zhou*, Lang Yang, Dazhi Bai, Qing Shi College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang, 443002, China. Ganoderma lucidum has been a well-known herb since ancient times and has the reputation of “Xiancao”. In modern times, Ganoderma Lucidum is used more in nourishing health products. Chinese medicine believes that Ganoderma lucidum is sweet, flat, and beneficial to qi and blood. It has the effect of soothing the mind, strengthening the spleen and nourishing the stomach. Clinically, it is also often used to treat insomnia, fatigue, and asthma. The Ganoderma lucidum real estate area has changed greatly from ancient to modern. The wild production area has changed from the ancient Wuyue Mountain to the current major lakes and seas. The cultivation of Ganoderma lucidum began in the 1950s, and the production area has changed to today’s Hubei, Hainan and other places. Currently cultivated Ganoderma lucidum. Has become the main body of Ganoderma lucidum. Hubei is an important real estate area. This paper mainly summarizes and analyzes the original plant and growth environment, cultivation techniques, pest control, medicinal properties, chemical composition, pharmacological effects and clinical use of the existing Chinese herbal medicine Ganoderma lucidum. From the research on the origin, traits, growth habits, medicinal properties and clinical application of Ganoderma lucidum, it provides practical information for the cultivation, use and pharmacological properties of Ganoderma lucidum. At the same time, the summary and analysis of Ganoderma lucidum information will be conducive to further research on the efficacy and marketization of Ganoderma lucidum. Keywords: Basic Nature, analysis, Ganoderma Lucidum ...

Hydroethanolic extract of Theobroma cacao beans is non toxic and attenuates oxydative stress induced by Naphtalene in Wistar rats

Research Article of Journal of Herbal Medicine Research Hydroethanolic extract of Theobroma cacao beans is non toxic and attenuates oxydative stress induced by Naphtalene in Wistar rats Feudjio A.F.1, Biapa N.P.1,2*, Kodjio. N3,Yembeau N.L.1, Kengne F.C.1, Nkwikeu N.P.1, Pieme C.A.2 Telefo P.B.1 1Research Unit of Medicinal Plant Biochemistry, Food Science and Nutrition, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 67 Dschang - Cameroon. 2Laboratory of Biochemistry, Department of Biochemistry and Physiological Sciences, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I – Cameroon, P.O. Box 1364 Yaoundé–Cameroon. 3Research Unit of Microbiology Research and Antimicrobial Substances, Department of Biochemistry, Faculty of Science, University of Dschang, PO Box 67 Dschang - Cameroon. Background: Oxidative stress is a situation where the cell no longer controls the excessive presence of toxic oxygen radicals. Many human diseases have a strong relationship with oxidative stress due to an imbalance between antioxidants and pro-oxidants. The objective of this study is to evaluate the in vivo antioxidant capacity of Theobroma cacao (T.cacao) beans extract and its acute toxicity. Methods: T. cacao beans were collected in the Obala locality (Center Cameroon) and then subjected to hydroethanolic extraction (70:30) at pH 3. The in vivo oxidative stress induction was done using naphthalene at 110 mg / kg and different doses of extracts (50 mg / kg, 100 mg / kg, and 200 mg / kg) were orally administered to rats. Some oxidative stress parameters helped to evaluate the antioxidant potential of the extract (superoxide dismutase (SOD), reduced glutathione (GSH) and malondialdehyde (MDA)). In addition, the acute toxicity of T. cacao was evaluated by the methods recommended by the ODCE. Test groups received respectively the extract at different doses (5000 mg / kg and 2000 mg / kg) against 10% of DMSO and distilled water as neutral controls ...

Anti-bacterial Activity of Aqueous and Methanolic Root Extracts of Medicinal Plant Heteropogon contortus

Research Article of Journal of Herbal Medicine Research Anti-bacterial Activity of Aqueous and Methanolic Root Extracts of Medicinal Plant Heteropogon contortus Ruvani Gamagea, Buddhika Hasanthia,*, Rajith Silvab, Daya Ratnasooriyab, Ranjith Pathiranab, Sujeewa Hettihewac, a National Science Foundation, Maitland Place, Colombo 7, Sri Lanka; b Department of Basic Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka; cDepartment of Pharmacy, Faculty of Medicine, University of Ruhuna, Karapitiya, Sri Lanka Synthetic drugs available for the treatment of chronic and infectious diseases are very expensive and some of them have become less effective due to the emergence of antibiotic resistance. Researchers are now focused on natural sources including plants and plant parts for the development of novel therapeutic agents. Therefore, this study evaluated in vitro anti-bacterial activity and phytochemical composition of aqueous and methanolic root extracts of Sri Lankan medicinal plant Heteropogon contortus against clinically significant pathogens, Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923). Agar well diffusion method and standard chemical tests were performed to evaluate anti-bacterial effect and phytochemical profile of the root extracts, respectively. The results revealed that each crude root extract exhibited anti-bacterial activity against both E. coli and S. aureus. The largest zones of inhibition against both E. coli and S. aureus were detected from the methanolic root extract at a concentration of 200 mg/mL and this is a novel finding. Phytochemical analysis of roots revealed the presence of bioactive constituents that account for the anti-bacterial potential, such as alkaloids, phenols and flavonoids. Thereby, root of H. contortus is a reliable source to develop potent, cheap and natural anti-bacterial agents. Future research focusing on high concentrations of different root extracts is recommended to further understand the anti-bacterial capability of H. contortus. Keywords: Heteropogon contortus, medicinal plant, root, anti-bacterial activity ...

ANTITUMOR ACTIVITY of EXTRACTS of Caulerpa taxifolia in the SARCOMA 180 TUMOR TREATMENT

Research Article of Journal of Herbal Medicine Research ANTITUMOR ACTIVITY of EXTRACTS of Caulerpa taxifolia in the SARCOMA 180 TUMOR TREATMENT Evandro Valentim da Silva1,2, Livia Nara Eugênio Pereira², Gabriela Cavalcante da Silva²; José Ferreira Silva Neto3, George Chaves Jimenez3, Fálba Bernadete Ramos dos Anjos1, Ivone Antonia de Souza2 1Department of Hstology and Embryology Universidad Federal of Pernambuco, Brazil; 2Department of Antibiotics Universidad Federal of Pernambuco, Brazil; 3Fisiology and Pharmacology Animal of Universidad Federal Rural of Pernambuco, Brazil; Cancer is a disease characterized by the multiplication and spread out of control in the form of anomalous cells. A normal cell becomes cancerous cells as a result of one or more mutations of DNA. Marine algae are a rich source of bioactive compounds, some of which are precursors of pharmacological tools and potentially useful substances for the development of new drugs. The present study aims to evaluate the antitumor activity of Caulerpa taxifolia front of Sarcoma 180 in albino mice (Mus musculus). The transplanted animals with sarcoma 180 (n = 24), were divided into four groups (n = 6) treated with two extracts: the MeOH extract (T1) and from hydroalcoholic C. taxifolia (T2) at a dose of 50 mg/kg ip. The control group (S1) received saline for the same route of administration. The default group (S2) received the reference drug to the tumor lineage. The data revealed that the S3 and S4 group responded to treatment with reduction of 63.6 and 42, 0 % respectively, as compared to EN/PA, when compared with the control group. The activities of extracts were higher than those of the reference drug for the Sarcoma 180. Keywords:phytotherapy, bioassay, bioactivity ...

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