Journal of Herbal Medicine Research


Ethnobotanical importance and phytochemical analyses of some selected medicinal plants used in Ado-Ekiti Local Government Area, Ekiti State, Nigeria.

Research Article of Journal of Herbal Medicine Research Ethnobotanical importance and phytochemical analyses of some selected medicinal plants used in Ado-Ekiti Local Government Area, Ekiti State, Nigeria. *Olanipekun, Mary .K , Adewuyi, Damilare and Adedeji, Damilola. E Department, Plant Science and Biotechnology, Ekiti-State University, Ado-Ekiti. The study investigated the ethnobotanical importance, phytochemical and proximate compositions of some selected medicinal plants such as Enantia chlorantha (Annonaceae), Momordica charantia (Cucurbitaceae), Telfaria occidentalis (Cucurbitaceae) and Morinda lucida (Rubiaceae) in Ado-Ekiti Local Government Area of Ekiti State, Nigeria. The review of the folk knowledge of the plants revealed that they were used in treating ailments such as gastrointestinal infections, malaria fever, typhoid, dermatitis, ringworm, jaundice, dysentery and used as antiseptic, digestive stimulant, blood tonic and blood booster. The qualitative screening of the plants revealed that all the plants contained a considerable amount of bio-active ingredients such as alkaloids, Saponins, tannins, flavonoids, cardiac glycosides, Terpenoids and total phenols. However, Momordica charantia has the highest number of alkaloids (20.68±0.27), Saponins (11.40±0.59) while Morinda lucida and Telfaria occidentalis have the lowest number of alkaloids (6.62±0.34) and Saponins (1.24±0.09). Similarly, Enantia chlorantha has the highest amount of flavonoids (15.56±0.00) and tannins (0.44±0.05). Morinda lucida stem bark has the lowest number of tannins (0.03±0.00) and flavonoids (0.94±0.00). Morinda lucida leaf has the highest amount of cardiac glycosides (0.07±0.03) while Morinda lucida stem bark and Momordica charantia does not have cardiac glycosides. Telfaria occidentalis has Terpenoids (0.09±0.00). Similarly, total phenols are high in Morinda lucida stem bark (0.58±0.00) while is low in Momordica charantia (0.21±0.00). The proximate composition showed that Telfaria occidentalis had the highest percentage of crude protein (31.49±1.32) and lowest percentage of crude fiber (9.08±0.27). Enantia chlorantha had the highest crude fat (5.17±0.24) and carbohydrates (50.31±1.56). Momordica charantia had the lowest percentage of total ash (2.67±0.16). Morinda lucida ...

Burns Inoculated with Staphylococcus aureus Healed by Leaf Sheath Extract of Pisang Ambon (Musa acuminata)

Review Article of Journal of Herbal Medicine Research Burns Inoculated with Staphylococcus aureus Healed by Leaf Sheath Extract of Pisang Ambon (Musa acuminata) Samsuar1, Pratika Viogenta1, Laila Susanti1, Yuli Wahyu Trimulyani1, Sutriyani1, Mohammad Kanedi2* 1Department of Pharmacy, Faculty of Mathematics and Sciences, Tulang Bawang University, Bandar Lampung, Indonesia 2Department of Biology, Faculty of Mathematics and Sciences University of Lampung, Bandar Lampung, Indonesia Review method: Single-blind; Peer reviewer comments: 1.  Using parts of banana to cure diseases is a common practice for people in homeland of genus Musa. However, scientific researches on biomedical effects of a specific banana cultivar still leaves many questions. This study is intended to find out the healing effect of leaf sheath extract of pisang Ambon or Gros Michel banana, a non-Cavendish cultivar of Musa acuminata, on burn wound intentionally innoculated with Staphylococcus aureus. Eighteen male rabbits were divided into six groups: P0, P1, P2, P3, P4, and P5 each consisting of three rabbits. P0 is rabbits that received no treatment as the negative control; P1, P2, P3 and P4 respectively are received banana extract of 6.25%, 12.5%, 55%, and 50%; P5 are given bioplacenton ointment as the positive control. To inflict burn wound, the withers area on the animal's back were shaved and anticepted using 70% ethanol and 10% iodine. On the shaved skin, burns was made by placing a heated brass coin weighted 10 g and a diameter of 2 cm, at 200oC for 5 seconds. All treatments were given topically three times daily. The recovery of burns is measured every three days for 14 days and the healing criteria were based on wound diameter changes. The results showed the extracts of pisang Ambon at the concentration of 12.5% and 25% are able to totally heal the wound on the day 14. While extracts of 6.25 % ...

Pharmacological studies on the renal and hepatic effect of methanol leaf extract of Lupinus arboreus in rats

Review Article of Journal of Herbal Medicine Research Pharmacological studies on the renal and hepatic effect of methanol leaf extract of Lupinus arboreus in rats *1Ohadoma SC, 2Akah PA, 2Nworu CS, 2Okoye TC 1Department of Pharmacology, College of Medicine, Imo State University, PMB 2000, Owerri, Nigeria. 2Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, P.O. Box 3219, Nsukka. Review method: Single-blind; Peer reviewer comments: 1. Objective: To investigate the renal and hepatic effect of methanol leaf extract of Lupinus arboreus using experimental rats. Methods: Three groups comprising five rats each were used. Group II and III received 50 and 100 mg/kg of extract respectively. Group I served as negative control and received only normal saline (5 ml/kg). All administration was done once daily for 28 days. Urea and creatinine for renal effect were determined using Quimica Clinica applicado (QCA Test Kit, Spain); while hepatic marker enzymes were evaluated using Assay Kits (Randox Laboratories Ltd., United Kingdom BT 294 QY). Histopathological evaluation was carried out using light microscopy. Student’s t-test, ANOVA and Turkey-Kramer test were employed to assess significance of difference due to administration of extract and the control. Results: Treatment with extract did not produce significantly (P>0.05) changes in the hepatic marker enzymes when compared with the control. The mean creatinine levels showed non-significantly (P>0.05) differences when compared with the control. At 100 mg/kg, the extract exhibited significantly (p<0.05) elevation of blood urea levels, as well as urea: creatinine ratio, compared with the negative control. Histopathological assessment revealed that the liver architecture was preserved and no occurrence of structural changes in the kidneys. Conclusion: The leaf extracts of Lupinus arboreus are devoid of deleterious renal and hepatic effects. Keywords: Lupinus arboreus, Chikadoma, leaf extract, renal and hepatic effects ...

Sirka (Vinegar): From Traditional Use To Scientific Approach

Review Article of Journal of Herbal Medicine Research Sirka (Vinegar): From Traditional Use To Scientific Approach Mohd Nauman Saleem*, Mohammad Idris** *Research Associate, Central Council for Research in Unani Medicine, New Delhi **Head, Departments of Ilm-us-Saidla and Ilm-ul-Advia, A & U Tibbia College, Karol Bagh, New Delhi Review method: Single-blind; Peer reviewer comments: 1. Traditional medicine is the summation of knowledge, skills and practices based on theories, beliefs and experiences which are indigenous to different cultures. Sirka (Vinegar) has a long historical background and besides its usage as a common condiment, food ingredient, preservative, flavoring and culinary agent it has also been extensively exploited as a potent medicinal substance. The use of vinegar to fight infections and other acute conditions dates back to Hippocrates who recommended a vinegar preparation named sikanjabeen for cleaning ulcerations and for the treatment of sores. Sikanjabeen was also used in conventional system of medicine by the name of oxymel. According to Unani classical literature, it is obtained after fermentation of various substances such as grapes, sugarcane, dried grapes, figs, jamun, honey, onions, grains etc and prepared by a specific procedure in which the juice of ingredient is taken in a vessel and kept in sunlight, until proper fermentation of that liquid takes place. Various actions and clinical indications have been elaborated in the Unani classical literature and some properties namely Anti-infective, Antihypertensive, Cardio-protective, Antitumor, Antiglycemic, Antioxidant and Antitubercular activities have been revalidated in the light of recent scientific researches. A number of clinical researches have also been performed to explore medicinal properties of Sirka (Vinegar). This review provides significant information on Sirka (Vinegar) as a traditional asset and furthers the scientific validation of pre existing facts. Keywords:  Sirka, Vinegar, Unani System of Medicine ...

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