Research Article of Open Journal of Gastroenterology and Hepatology
VITAMIN D DEFICIENCY IN CHILDREN AGED 6 – 11 AT VIETNAM NATIONAL CHILDREN’S HOSPITAL
Luu Thi My Thuc*, Nguyen Thi Hang, Nguyen Thi Hang Nga, Ha Thi Hong Giang, Nguyen Thi Thuy Hong**
*Vietnam National Children’s Hospital, Vietnam
** Hanoi Medical University, Vietnam
Objective: Describe the situation of vitamin D deficiency in children aged 6 – 11 years at Vietnam National Children’s Hospital. Method: Cross-sectional study. Results: In 155 healthy children in the study, vitamin D deficiency (25(OH)D serum level < 50 nmol/l) was 23.9%. Common clinical symptoms of vitamin D deficiency were long bone pain (32%) and low ionized calcium level (83.8%). There was inverse linear correlation between vitamin D level, weight-for-age z score (WAZ) (r= –0.266 and p<0.01) and BMI-for-age z score (BAZ) (r= –0.241 and p<0.01). Conclusion: There was a high prevalence of vitamin D deficiency in healthy children aged 6-11 years (23.9%), the most common clinical symptoms of vitamin D deficiency were long bone pain and low serum level of ionized calcium, which have value in vitamin D deficiency diagnosis.
Keywords:Vitamin D deficiency, children aged 6 – 11 years, primary school age, Vietnam National Children’s Hospital
How to cite this article:
Luu Thi My Thuc, Nguyen Thi Hang, Nguyen Thi Hang Nga, Ha Thi Hong Giang, Nguyen Thi Thuy Hong. VITAMIN D DEFICIENCY IN CHILDREN AGED 6 – 11 AT VIETNAM NATIONAL CHILDREN’S HOSPITAL.Open Journal of Gastroenterology and Hepatology, 2019, 2:16. DOI: 10.28933/ojgh-2019-10-0407
1. M. F. Holick, N. C. Binkley, H. A. Bischoff-Ferrari et al (2011). Evaluation,
treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab, 96(7):1911-30.
2. A. Laillou, F. Wieringa, T. N. Tran et al (2013). Hypovitaminosis D and mild hypocalcaemia are highly prevalent among young Vietnamese children and women and related to low dietary intake. PLoS One, 8(5): e63979.
3. B. K. Le Nguyen, H. Le Thi, V. A. Nguyen Do et al (2013). Double burden of undernutrition and overnutrition in Vietnam in 2011: Results of the SEANUTS study in 0.5-11-year-old children. Br J Nutr, 110 Suppl 3: S45-56.
4. B. R. Kar, S. L. Rao and B. A. Chandramouli (2008). Cognitive development in children with chronic protein energy malnutrition. Behav Brain Funct, 4: 31.
5. B. K. Poh, N. Rojroongwasinkul, B. K. Nguyen et al (2016). 25-hydroxy-vitamin D demography and the risk of vitamin D insufficiency in the South East Asian Nutrition Surveys (SEANUTS). Asia Pac J Clin Nutr, 25(3): 538-48.
6. WHO (2007). Bulletin of the World Health Organization, 660-667.
7. WHO (2007). WHO AnthroPlus for Personal Computers Manual.
8. Viện dinh dưỡng (2010). Tổng điều tra dinh dưỡng năm 2009 – 2010 (National Institute of Nutrition (2010). National nutrition survery 2009 – 2019)
9. Nguyễn Thị Mai Anh (2006). Tình trạng dinh dưỡng và một số yếu tố liên quan của học sinh 6-8 tuổi trường tiểu học Yên Thường, Gia Lâm, Hà Nội (Nutritional status and some relevant factors in children aged 6 – 8 of Yen Thuong primary school, Gia Lam, Hanoi).
10. L. H. Foo, Q. Zhang, K. Zhu et al (2009). Low vitamin D status has an adverse influence on bone mass, bone turnover, and muscle strength in Chinese adolescent girls. J Nutr, 139(5): 1002-7.
11. T. R. Neyestani, M. Hajifaraji, N. Omidvar et al (2012). High prevalence of vitamin D deficiency in school-age children in Tehran, 2008: a red alert. Public Health Nutr, 15(2): 324-30.
12. A. Soliman, V. De Sanctis, A. Adel et al (2012). Clinical, biochemical and radiological manifestations of severe vitamin D deficiency in adolescents versus children: response to therapy. Georgian Med News(210): 58-64.
13. R. Alemzadeh, J. Kichler, G. Babar et al (2008). Hypovitaminosis D in obese children and adolescents: relationship with adiposity, insulin sensitivity, ethnicity, and season. Metabolism, 57(2): 183-91.
14. Sarah M Shaikhoon Abdulmoein E Al-Agha, Mada A Sultan and Heba S Alsheikh (2016). Weight and Body Mass Index in Relation to Vitamin D Status in Healthy 4–13 Years Old Children in Saudi Arabia. Journal of Medical and Health Sciences: 2319-9865
15. Kim BR Roh YE, Choi WB (2016). Vitamin D deficiency in children aged 6 to 12 years: single center’s experience in Busan. Ann Pediatr Endocrinol Metab, 21(3): 149–154.
16. Kostecka M (2016). Frequency of consumption of foods rich in calcium and vitamin D among school-age children. Rocz Panstw Zakl Hig, 67(1): 23-30
17. Du X Zhu K, Cowell CT, et al (2005). Effects of school milk intervention on cortical bone accretion and indicators relevant to bone metabolism in Chinese girls aged 10-12 year in Bejing. Am J Clin Nutr, 81: 1168-75.
18. Stuart JJ Ganmaa D, Sumberzul N, et al (2017). Vitamin D supplementation and growth in urban Mongol school children: Results from two randomized clinical trials. PLoS One, 12(5): e0175237.
19. Mølgaard C Hoppe C, Michaelsen KF (2006). Cow’s milk and linear growth in industrialized and developing countries. Annu Rev Nutr, 26: 131-73.