Open Journal of Gastroenterology and Hepatology


POST-VAGOTOMY GASTROPARESIS – A CASE REPORT

Case Report of Open Journal of Gastroenterology and Hepatology POST-VAGOTOMY GASTROPARESIS – A CASE REPORT Oguntoye Oluwatosin Oluwagbenga1, Yusuf Musah1, Olowoyo Paul1, Erinomo Olagoke2, Omoseebi Oladipo2, Soje Michael Osisiogu1,Oguntoye Oluwafunmilayo Adenike3, Fatudimu Oluwafemi4 1Department of Internal Medicine, Federal Teaching Hospital Ido-Ekiti and Afe Babalola University Ado-Ekiti, Nigeria; 2Department of Morbid Anatomy, Federal Teaching Hospital Ido-Ekiti and Afe Babalola University Ado-Ekiti, Nigeria; 3Department of Internal Medicine, Federal Teaching Hospital Ido-Ekiti, Nigeria; 4Department of Surgery, Federal Teaching Hospital Ido-Ekiti, Nigeria. We present Mr M.A. a 27 year old Nigerian of the Yoruba tribe who has been having recurrent dyspeptic symptoms for 5 years but not previously endoscopically evaluated for peptic ulcer disease who now presented with six days history of abdominal pain which was initially epigastric but later became generalized associated with four episodes of vomiting and a day history of abdominal distension and fever. He was acutely ill-looking and dehydrated. The Abdomen was moderately distended, does not move with respiration, generalized tenderness with guarding and rebound tenderness, intra-abdominal organs were difficult to palpate due to the guarding. Bowel sound was absent. Examination of the other systems was not remarkable. A provisional diagnosis of Generalized peritonitis likely secondary to perforated peptic ulcer was made. He had an emergency exploratory laparotomy under general anaesthesia. He was commenced on intravenous fluids and parenteral proton pump inhibitor(PPI) and antibiotics. Intra-op findings include 2 liters of bilious peritoneal fluid, Multiple fibrous adhesions, a 2.5cm x 2cm gastric perforation at the anterior wall of the antrum and a grossly normal bowel. The surgical operation performed was a Graham Omental patch closure of the gastric defect with Bilateral Truncal Vagotomy and Peritoneal lavage. Post-operative state was satisfactory and he was later discharged. He presented at the gastroenterology out-patient clinic eight months later with complaints of early satiety, feeling ...

Virological response of hepatitis Delta infection to treatment with Pegylated Interferon alpha 2a in a high prevalence country

Research Article of Open Journal of Gastroenterology and Hepatology Virological response of hepatitis Delta infection to treatment with Pegylated Interferon alpha 2a in a high prevalence country Servais Albert Fiacre Eloumou Bagnaka1, Winnie Tatiana Bekolo Nga1, Gabin Ulrich Kenfack2, Yvanne Getty Bilo’o Mfoula1, Mathurin Kowo2, Christian Tzeuton1, Henry Namme Luma2, Oudou Njoya2, Dominique Noah Noah1, Firmin Ankouane Andoulo2 1Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon 2Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon The prevalence of Hepatitis Delta Virus (HDV) infection in Cameroon is 11.01%. Pegylated interferon alpha 2a (PEG-IFN α 2a) is the standard treatment worldwide. This study aimed to describe the virological response to this drug in cameroonians. Methods: We carried out a cross-sectional study from 1 January 2012 to 31 December 2018. It took place in eleven (11) health facilities of Yaoundé and Douala. Patients with HDV infection and treated with PEG INF α 2a for at least 48 weeks were included. The primary endpoint was Virologic Response (VR) and secondary endpoints were Rapid Virologic Response (RVR) and Late Virologic Response (LVR). Results: We included 133 patients. The mean age was 36.33 ± 10.9 years. The male sex accounted for 65.41% of cases. The VR was 67.67%.  Leukopenia, fever, headache, asthenia and abdominal pain were the most common adverse events in 88.72%, 68.42%, 53.38%, 45.11% and 35.34% of cases respectively. Factors associated with VR were the presence of diabetes (aOR= 4.32; CI95% [1.22 - 15.30], p= 0.023), fever (aOR= 5.16, CI95% [1.48 - 18.04], p=0.01) and ALT levels greater than 40 IU/l (aOR= 3.69, IC95% [1.15 - 11.18], p= 0.028). Conclusion: VR is high in cameroonians. The presence of diabetes and elevated transaminases are factors associated with this virologic response. We recommend the use of interferon treatment for patients with HDV infection ...

Usefulness of Castor Oil and Elobixibat and Lactulose and Ascorbic Aid (Movicol) for Bowel Preparation for Colon Capsule Endoscopy:A Case Report

Case Report of Open Journal of Gastroenterology and Hepatology Usefulness of Castor Oil and Elobixibat and Lactulose and Ascorbic Aid (Movicol) for Bowel Preparation for Colon Capsule Endoscopy:A Case Report Naoki Hotta Department of Internal Medicine, Division of Gastroenterology, Masuko Memorial Hospital, Aichi, Japan. Colon capsule endoscopy was approved for reimbursement under the national health insurance system of Japan in 2014. However, the capsule excretion rate after recommended bowel preparation reportedly ranges from 70% to 90%, and administration of boosters is also necessary. The caster oil-based booster had an emission rate of 97%, but required a total water content of 3L. Some patients have been tested for the second and third time since the test was started in 2014. There is an opinion that these patients could reduce the booster more, and this time we will use the booster with mobiprep to perform the booster on the day with 350 ml. Keywords: Castor Oil ,Elobixibat , Lactulose and Ascorbic Aid(Movicol) ...

Usefulness of Castor Oil and Elobixibat and Lactulose for Bowel Preparation for Colon Capsule Endoscopy in the patients on Dialysis -Including examination of small intestinal lesions-

Research Article of Open Journal of Gastroenterology and Hepatology Usefulness of Castor Oil and Elobixibat and Lactulose for Bowel Preparation for Colon Capsule Endoscopy in the patients on Dialysis -Including examination of small intestinal lesions- Naoki Hotta Department of Internal Medicine, Division of Gastroenterology, Masuko Memorial Hospital, Aichi, Japan. Colon capsule endoscopy was approved for reimbursement under the national health insurance system of Japan in 2014. Dialysis patients are potentially susceptible to bleeding because of the fragile intestine, impaired platelet function, or oral administration of nonsteroidal antiinflammatory drugs (NSAIDs) or anticoagulants. However, the capsule excretion rate after recommended bowel preparation reportedly ranges from 70% to 90%, and administration of boosters is also necessary. For dialysis patients, liquid loading is a problem. The patient on dialysis has moisture restrictions. The caster oil-based booster had an emission rate of 97%, but required a total water content of 3L. A study was conducted on dialysis patients using a protocol in which castor oil was supplemented with Elobixibat and Lactulose to determine whether booster volume could be reduced and elimination rates improved. Keywords: Castor Oil ,Elobixibat ,Colon Capsule Endoscopy ,Patients on Dialysis ...

Dr. Mohammed Naeem
Chair, Patient Safety Reporting/Consultant Pediatric Intensivist/ Head PICU (A)/ Assistant Professor, Dept. of Pediatrics. Ministry National Guard Health Affairs Riyadh, Saudi Arabia

Dr Toru Ishikawa
Gastroenterology, Saiseikai Niigata Daini Hospital

Dr. George Paraskevas
Associate Professor of Anatomy Orthopedic Surgeon, Department of AnatomyMedical School, Aristotle University of Thessaloniki, Post Box: 300, Post Code: 54124, Thessaloniki, Greece

Dr. Mahaboob Vali Shaik
Assistant Professor/Senior Scientist, Department of Genetics & stem cell Research, Narayana Medical College & Hospitals

Dr. Ifeadike Chigozie Ozoemena
Associate Professor, Department of Community Medicine, Faculty of Medicine, Nnamdi Azikiwe University

Dr. Eduardo de Moura GH
Professor, niversity of São Paulo School of Medicine, São Paulo, Brazil

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