Open Journal of Gastroenterology and Hepatology


Living Style of Diabetic Patients Type 2

Research Article of Open Journal of Gastroenterology and Hepatology Living Style of Diabetic Patients Type 2 Gomes, K.K.L¹; Lima, A.A.F² ¹Enfermeira da Atenção Básica e Especialista em Saúde da Família; ²Psicóloga do NASF e Especialista em Saúde Mental e Dependência Química Introduction: Due to the aging process, there are disabling chronic diseases that have gained greater evidence in the public health scenario. Among them is diabetes mellitus (DM), which is one of the most common chronic diseases among the elderly. Life style is an important determinant of glycemic control in type 2 diabetic patients. Objectives: To describe the lifestyle of type 2 diabetic patients treated at the Family Health Basic Unit III, in the city of Santa Cecília-PB. Methodology: Descriptive study, population composed of 55 diabetics, adults, type 2, data collected from a pre-structured interview. Results and Discussion: 56% female, 44% male, 29% have good eating habits, 8% practice regular physical exercises, 75% are overweight, 20% are medicated. The World Health Organization considers that the diet of the diabetic is one of the factors responsible for keeping the glycemic levels within desirable limits. The survey found that only 29% of those involved have a proper diet with a very low index. Many studies suggest that sedentarism favored by modern life is a risk factor as important as inadequate diet in the etiology of obesity and has a direct and positive relationship with the increased incidence of DM 2 in adults. The practice of physical exercise for people living with diabetes is very low. Only 8% reported regular exercise. Conclusion: It is important to emphasize that glycemic control depends, in addition to drug therapy, on changes in lifestyle. Since 90% of respondents said they had good adherence to drug treatment. It is necessary to implement strategies that seek to raise awareness about ...

Incidence of Diabetic Foot in Patients With Diabetes Mellitus in a Basic Health Unit

Research Article of Open Journal of Gastroenterology and Hepatology Incidence of Diabetic Foot in Patients With Diabetes Mellitus in a Basic Health Unit Nascimento, J.W.A¹; Silva, E.C.S²; Siqueira, A.C.P.R³; Jesus, S.B4 1,2Nursing Student in the Católica of Pernambuco University; br; 3Medical Student In Católica of Pernambuco University; 4Docent/Researcher in the Católica of Pernambuco University Introduction: Diabetic neuropathy is one of the complications that integrates the pathogenic diabetic foot triad. This neuropathy leads to a foot sensory loss, making the patient vulnerable to minor injuries that could precipitate lesions, subsequent infection and foot amputation. Therefore, the diagnosis needs to come from a complete and detailed physical examination. Objective: The present study aims to investigate the incidence of diabetic foot in diabetic patients who are users of the Basic Health Unit (BHS) in the city of Olinda, Pernambuco. Methodology: The sample of this descriptive exploratory of quantitative methods study was composed of 50 diabetic users of the Basic Health Unit. After signing a Free and Informed Consent Form, a questionnaire was applied regarding the perception of the diabetic on signs and symptoms which are observed in the diabetic foot, proceeding with a thorough evaluation of the feet using 10g of monofilament and performing the Pin Prick Test. Results and Discussion: In total, 70% of patients reported poor glycemic control, 63% reported neuropathic symptoms such as numbness and tingling in the feet and 57% of the evaluated patients have thickened nails and dried or scaly feet. Regarding the vascular evaluation 47% of the evaluated presented with a decreased pedal pulse and 7% presented with this same pulse absent, while 40% had decreased posterior tibial pulse and 7% did not present any pulse at palpation. Regarding the sensitivity assessment, 30% of diabetics presented abnormal results in one of the feet and 7% had no painful ...

Obesity Induced by High Fat Diet Impairs Glucose Tolerance and Insulin Sensitivity in Rats

Research Article of Open Journal of Gastroenterology and Hepatology Obesity Induced by High Fat Diet Impairs Glucose Tolerance and Insulin Sensitivity in Rats Silva, L.M.P1; César, L.C.C1; Silva, J.J.T2; Duarte, G.I.B.P3; Rabelo, L.A4; Souza, V.N5 1Undergraduate Students-Biomedicine- CB – UFPE; 2PhD Student of Postgraduate Program in Biochemistry and Physiology - CB-UFPE. 3Professor/Researcher - dDpartment of Physiology and Pharmacology – CB – UFPE. 4Professor/Researcher- Institute of Biological Sciences and Health – ICBS – UFAL. 5Professor/Researcher - Department of Physiology and Pharmacology– CB-UFPE Introduction: Obesity is a chronic disease, besides a risk factor for cardiovascular diseases, nowadays, it is characterized as a worldwide epidemic. The food imbalance and physical inactivity are factors that contribute to the emergence of obesity as well as diabetes. Objective: To evaluate the injury on glucose tolerance and insulin sensitivity in obese rats induced by high fat diet. Methodology: Male Rats Wistar (8 weeks old) were submitted to the standard diet (chow group, 11.8% kcal-Lipids; n = 5) and dietary intervention with high fat diet during 8 weeks (HFD group, 58.4% kcal-Lipids; n= 5). It was evaluated the body weight weekly, and fasting and fed blood glucose. At the end of the experimental period, was measured the glucose tolerance, insulin sensitivity and gluconeogenesis. After the animal sacrifice, it was analyzed relative weight of white adipose tissue, as well as the adipocytes diameter (epididymal white adipose tissue) and circulating levels of leptin. Results and Discussion: The group HFD presented higher body weight (from the 2nd week of diet), an increase accumulation of epididymal and perirenal white adipose tissue. In addition, in these animals, it was observed a significant increase in the adipocytes diameter and the levels of leptin in plasma when compared to animals chow, indicating obesity with increased release of cytokines. In HFD group, the fasting blood glucose levels ...

Consumption of High Fat Diet Induces Obesity Associated to Hepatic Steatosis in Rats

Research Article of Open Journal of Gastroenterology and Hepatology Consumption of High Fat Diet Induces Obesity Associated to Hepatic Steatosis in Rats Silva, L.M.P1; Pereira, J.B1; s Neves, V.P.F.F2; Duarte, G.I.B.P3; Rabelo, L.A4; Souza, V.N5 1Undergraduate Student-Biomedicine- CB – UFPE; 2Undergraduate Student-Enfermagem- UFAL. 3Professor/Researcher - Department of Physiology and Pharmacology – CB – UFPE. 4Professor/Researcher- Institute of Biological Sciences and Health – ICBS – UFAL. 5Professor/Researcher - Department of Physiology and Pharmacology – CB – UFPE. Introduction: The high intake of carbohydrates and lipids is one of factors that contribute to the onset of Metabolic Syndrome (MetS), a complex clinical situation which brings together, besides obesity, several cardiovascular and metabolic risk factors, including non-alcoholic fatty liver disease (NAFLD). Objective: To develop a hyperlipidemic dietetic animal model to obesity associated with NAFLD. Methodology: Male Rats Wistar (8 weeks old) were submitted to the standard diet (chow group, 11,8% kcal- lipids) and hypercaloric and hyperlipidemic during 8 weeks (HFD group, 58,4% kcal-lipids). After the dietary intervention, body weight, plasma and hepatic lipid profile (triglycerides, total cholesterol, VLDL and fatty acids) and adiposity index were evaluated. Moreover, histological assessment of hepatic lipid deposition and fibrosis, as well as the hepatic damage marker (alanine aminotransferase-ALT) were evaluated. Results and Discussion: Comparing to the chow group, HFD animals presented higher body weight, both in fasting and in the fed state, increased abdominal circumference, adiposity index, as well as plasma levels of total cholesterol and non-esterified fatty acids, characterizing the dietary phenotype of obesity. In addition, the HFD group had a significant decrease in brown adipose tissue, together with the lowest weight loss induced by 16h overnight fasting, suggesting a decrease in energy expenditure. In the liver, the HFD group presented a significant increase in the levels of triglycerides, cholesterol, VLDL and non-esterified fatty acids, and, qualitatively, ...

Dr. Mohammed Naeem
Chair, Patient Safety Reporting/Consultant Pediatric Intensivist/ Head PICU (A)/ Assistant Professor, Dept. of Pediatrics. Ministry National Guard Health Affairs Riyadh, Saudi Arabia

Dr Toru Ishikawa
Gastroenterology, Saiseikai Niigata Daini Hospital

Dr. George Paraskevas
Associate Professor of Anatomy Orthopedic Surgeon, Department of AnatomyMedical School, Aristotle University of Thessaloniki, Post Box: 300, Post Code: 54124, Thessaloniki, Greece

Dr. Mahaboob Vali Shaik
Assistant Professor/Senior Scientist, Department of Genetics & stem cell Research, Narayana Medical College & Hospitals

Dr. Ifeadike Chigozie Ozoemena
Associate Professor, Department of Community Medicine, Faculty of Medicine, Nnamdi Azikiwe University

Dr. Eduardo de Moura GH
Professor, niversity of São Paulo School of Medicine, São Paulo, Brazil

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1.Gomes, K.K.L; Lima, A.A.F. Living Style of Diabetic Patients Type.Open Journal of Gastroenterology and Hepatology, 2018, 1:5. DOI:10.28933/ojgh-2018-05-1005

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