Editorial Board of Journal of Stroke Research
Dr. Mushfiquddin Khan
Department of Pediatrics,
Medical University of South Carolina,
508 CRI, 173 Ashley Ave, Charleston, SC, USA.
Biography & Research Interest
Welcome Dr. Mushfiquddin Khan to Join the Editorial Board of Journal of Stroke Research. Dr. Mushfiquddin Khan’s major research interest is to investigate the neuropharmacology of CNS trauma with focus on stroke (transient and permanent), traumatic brain injury (TBI), spinal cord contusion injury (SCI) and lumbar spinal stenosis (LSS). The investigations have targeted both neuroprotection and neurorestoration for optimal functional recovery following CNS trauma. Dr. Mushfiquddin Khan’s bioorganic background (Ph.D.) and neuropharmacology training (Postdoc) prepared him to study design, prepare and administer drugs to animal models of CNS trauma and determine their efficacy. These studies helped to develop expertise in animal models (rat and mouse) of acute/chronic brain injury (stroke, TBI SCI and LSS), evaluation of neurobehavioral and neurological functions, measurements of physiologic parameters as well as cerebral blood flow. To understand the neurorestoration mechanisms, Dr. Mushfiquddin Khan devoted efforts to investigating the role of proteases, lipases and bioactive lipid mediators in neuronal injury and the significance of angiogenesis and neurogenesis in brain repair mechanisms. To support the animal studies, neuronal and glial cell culture models and pharmacological agents are used to elucidate the cellular and molecular mechanisms. Dr. Mushfiquddin Khan remained focused on neurovascular protection, neurorepair process and mechanisms of cross talk between neurons and glial cells, as evident from peer reviewed high impact more than 85 publications and a number grant awards.
Key words of interest:
Stroke, Cerebrovascular disease, Endothelial dysfunction, TBI, Neuroprotection, Neurorepair, Neurobehavioral function, Nitric oxide, Nitrosylation
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