Welcome Dr. Yuan Soon Ho to International Journal of Food and Nutrition Research

Dr. Yuan Soon Ho
Distinguished Professor/Director
Graduate Institute of Medical Science
College of Medicine, Taipei Medical University

Biography & Research Interest

Welcome Dr. Yuan Soon Ho to Join the Editorial Board of International Journal of Food and Nutrition Research.


Upon completion of his doctorate in Biochemistry field at the National Taiwan University in 1994 he joined the faculty at Graduate Institute of Biomedical Technology, Taipei Medical University where he directed research combining genomics and breast cancer research with translational research. Dr. Ho is currently as the Director of Graduate Institute of Medical Science, Taipei Medical University (2014~). His research team found that nicotinic receptors were detected in the breast tumor tissues. The role of nicotinic receptor was demonstrated as a cell growth promoting factor evidenced by SiRNA knock down and tet-off overexpression animal experiments. This finding led to the development of powerful antitumor agents, and the cloning of nicotinic receptor gene linked to breast cancer and now being investigated as a potential therapeutic target for smoking-induced breast and other cancers. Dr. Ho is also invited as an editor of the Scientific Report (oncology field) and Plos One journals. It is expected that these works will lead to further establish a translational research team by which coordinate the basic and clinical researchers to focus on the mechanisms of breast cancer formation.

Scientific Members:

The member of council in Taiwan Tea Association (2012~)
The director of academic committee in Taiwan Tea Association (2012~)
The member of council (director of academic committee) in The Taiwan Oncology Society (2015~)

Selected publications
1 Wu CH, Ho YS, Tsai CY, et al. In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter. Int J Cancer 2009; 124:2210-2219
2 Lee CH, Huang CS, Chen CS, et al. Overexpression and activation of the alpha9-nicotinic receptor during tumorigenesis in human breast epithelial cells. J Natl Cancer Inst 2010; 102:1322-1335
3 Wu CH, Lee CH, Ho YS. Nicotinic acetylcholine receptor-based blockade: applications of molecular targets for cancer therapy. Clin Cancer Res 2011; 17:3533-3541
4 Jin G, Lee SW, Zhang X, et al. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1. Mol Cell 2015; 58:989-1000


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