Research Article of American Journal of Microbiology and Immunology
Antimicrobial Properties of Prosopis cineraria stem bark
Saif Al Ghais, Vibha Bhardwaj*, Pramod Kumbhar
Environment Sustainability, Department Environment Protection & Development Authority (EPDA), Ras Al Khaimah, UAE
Infectious diseases are the most common causes of morbidity and mortality in developing countries. Nowadays, medicinal plants play a major role in treatment of infectious diseases and they are easily available and more affordable as compared to synthetic compounds. The emerging trends of multidrug resistance among several groups of microorganisms against different classes of antibiotics led different researchers to develop efficient drugs from plant sources to counter multidrug resistant strains. This study investigated two different concentration of methanol extracts of stem bark of Prosopis cineraria to determine their efficacy against multidrug resistant microbes.
Powdered barks of the tree were treated with methanol using hot extraction method. Crude methanol extracts of the bark of P. cineraria was investigated for their antibacterial activity against a wide range of bacteria (both gram-positive and gram-negative) by disc diffusion method. Ciprofloxacin was used as standard.
Multidrug resistant (MDR) strains of Bacillus subtilis (ATCC 6633), E. coli (ATCC 8739), Salmonella enterica (ATCC 14028), Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 27853) were used in the study. The methanolic bark extracts of P. cineraria showed a remarkable inhibition of the microorganisms. The potency shown by these extracts recommends their use against multidrug resistant microorganisms. The present study suggests that the methanol extract of the stem bark of P. cineraria exhibited a potential antibacterial activity against the tested microorganisms and could be a potential source of new antimicrobial agents.
Keywords: Prosopis cineraria, antibacterial, ciprofloxacin, bark, microorganisms
How to cite this article:
Saif Al Ghais, Vibha Bhardwaj, Pramod Kumbhar. Antimicrobial Properties of Prosopis cineraria stem bark. American Journal of Microbiology and Immunology, 2020 5:7. DOI: 10.28933/ajmi-2020-06-2105
1. Akram M, Shahid M, Khan AU (2007) Etiology and Antibiotics Resistance Pattern of Community Acquired Urinary Infections in J N M C Hospital Aligarh India. Ann Clin Microbiol Antimicrob 6: 4.
2. Al Ghais S, Bhardwaj V and Kumbhar P (2020a). Prosopis cineraria (Ghaf): An Unconventional Dessert protein rich supplement. American Journal of Agricultural Research, 5:94. https://escipub.com/ajar-2020-04-1805/
3. Al Ghais S, Bhardwaj V and Kumbhar P (2020b). Prosopis cineraria (Ghaf): A potential desert nutraceutical. International Journal of Development Research, Vol. 10, Issue, 03, pp. 34162-34165.
4. Andrew LH, et al. Rapid analysis of Pharmacology for infectious diseases. Curr Top Med Chem. 2011;11:1292–300.
5. Begashaw B, Mishra B, Tsegaw A and Shewamene Z (2017). Methanol leaves extract Hibiscus micranthus Linn exhibited antibacterial and wound healing activities. BMC Complementary and Alternative Medicine 17:337.
6. Food, Medicine and Health Care Administration and Control Authority (FMHACA). Antimicrobial use, resistance and containment baseline survey, syntheses of findings, Addis Ababa, Ethiopia, 2009.
7. Gibbons S (2005) Plants as a source of bacterial resistance modulators and anti-infective agents. Phytochem Rev 4: 63-78.
8. Gottlieb OR, Borin MR, Brito NR (2002) Integration of ethnobotany and phytochemistry: dream or reality? Phytochemistry 60: 145-52.
9. Kapoor B. B. S., Bansal R (2013). Antimicrobial Screening of Some Medicinal Tree Species of Nagaur District of Rajasthan. International Journal of Herbal Medicine; 1 (4): 10-11.
10. Krishnaiah D, Devi T, Bono A, Sarbatly R. (2009). Studies on phytochemical constituents of six Malaysian medicinal plants. Journal of Medicinal Plants Research.;3(2):67–72.
11. Khan R, Islam B, Akram M, Shakil S, Ahmed A, Ali SM, Siddidui M, Khan AU (2009) Antimicrobial activity of five herbal extracts against multi drug resistant (MDR) strains of bacteria and fungus of clinical origin. Molecules 14: 586-97.
12. Okwori AE (2007). Antibacterial activities of Ageratum conyzoides extracts on selected bacterial pathogens. Internet J Microbiol.;4(1):34–56.
13. Singh B and Bhat TK (2003) Potential therapeutic applications of some antinutritional plant secondary metabolites. J Agric Food Chem 51: 5579–97.
14. Sohel A, (2010). Antibacterial activity of the ethanol extracts of Hibiscus rosasinensis leaves and flowers against clinical isolates of bacteria. Bangladesh J Life Sci.;22(2):65–73.
15. Tomoko N, Takashi A, Hiromu T, Yuka I, Hiroko M, Munekazu I, Tsutomu N, Kazuhito W (2002) Antibacterial activity of extracts preparated from tropical and subtropical plants on methicillin-resistant Staphylococcus aureus. J Health Sci 48: 273–76.
16. Uddin, B., Nahar, T., Khalil, M.I. and Hossain, S. In vitro antibacterial activity of the ethanol extracts of Paederia foetida L. (Rubiaceae) leaves. Bangladesh J. life Sci. 2007;19(2): 141–143.
17. Velmurugan V, Arunachalam G and Ravichandran V (2010). Antibacterial activity of stem bark of Prosopis cineraria (Linn.) druce. Archives of Applied Science Research, 2 (4): 147-150
This work and its PDF file(s) are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.