PREVALENCE AND ASSOCIATIONS OF HEPATITIS B VIRUS INFECTION AMONG STUDENTS OF TRADITIONAL SCHOOLS, EAST NILE LOCALITY, KHARTOUM, SUDAN


PREVALENCE AND ASSOCIATIONS OF HEPATITIS B VIRUS INFECTION AMONG STUDENTS OF TRADITIONAL SCHOOLS, EAST NILE LOCALITY, KHARTOUM, SUDAN


Amin A. Mohamed Musa1, Sondos A. Abd Alrahem2, Shymaa A. Saeed2, Altayeb Abdulmonem4 , Khalid A. Mohamed 3, Mamoun M A Homeida 1

1Paediatrics, University of Medical Sciences and Technology, Sudan; 2 Medical Laboratory Sciences, Department of Microbiology, University of Medical Sciences and Technology, Sudan; 3 Sidra Medicine and Weil Cornel Medicine QA; 4Department of Surgery, Ibn Sina Hospital Ministry of Health, Khartoum, Sudan


Background: Hepatitis B virus (HBV) infection is a major health problem causing considerable morbidity and mortality from both acute infection and chronic sequels including chronic hepatitis, cirrhosis and hepatocellular cancer.

Aim: To estimate the prevalence of hepatitis B virus infection and the associated factors among children and adolescent in the traditional schools, East Nile locality.

Methods: Descriptive cross-sectional school-based study. Sero-prevalence survey was conducted among school children and adolescent aged 2–19 years. Total sample of 880 students were tested for Hepatitis B surface antigen (HBsAg) in serum using immune-chromatographic assay. Data were analyzed using IBM statistical package for social sciences version 20 with statistical significance of (p<0.05).

Results: A total of 4.2% tested positive for HBsAg, (3.2%) among children and (4.3%) among adolescent, this is lower than the reported prevalence in the country. There was no significant association between the pre-determined risk factors and hepatitis B virus infection in the study group.

Conclusion: The prevalence of HBV infections in this study was lower than the overall prevalence in Sudan. Further studies are needed to evaluate the risk factors for hepatitis B virus infection among children and adolescents in Sudan. Hepatitis B virus vaccine should be implemented in the vaccination program for children, in addition to awareness campaigns about the virus and transmission methods.


Keywords: Hepatitis B Virus, Children, Adolescent, Traditional Schools.

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How to cite this article:

Amin A. Mohamed Musa, Sondos A. Abd Alrahem, Shymaa A. Saeed, Altayeb Abdulmonem, Khalid A. Mohamed, Mamoun M A Homeida.Prevalence and Associations of Hepatitis B Virus Infection among Students of Traditional Schools, East Nile Locality, Khartoum, Sudan. American Journal of Microbiology and Immunology, 2021, 6:10. DOI: 10.28933/ajmi-2021-08-0805


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