CARCINOMA OF THE UPPER LIP- CASE REPORT AND REVIEW OF THE LITERATURE

CARCINOMA OF THE UPPER LIP- CASE REPORT AND REVIEW OF THE LITERATURE

Luigi Clauser, MD,MFS¹, Riccardo Luoni Orsi, DMD¹, Andrea Edoardo Bianchi, MD,MFS^1,2

¹Unit of Maxillo-Facial Surgery, Istituto Stomatologico Italiano, Via Pace, 21, 20122 MILANO, Italy; ²Università UniCamillus-Saint Camillus International University,Via di Sant’Alessandro,8-00131 ROME, Italy

Aim: Carcinoma of the upper lip is less frequent than in the lower lip. It affects both sexes in equal proportion. Histologically basal cell carcinomas are numerically preponderant and are observed in 50% of cases in the skin and adnexae in the oro-facial area.

Methods: The authors describe a major defect of the right upper lip after a wide resection for carcinoma. Immediate reconstruction was performed  with rotation of a flap from the lower lip  according to Estlander. The postoperative oral deformity persisted after radiotherapy and during  the  subsequent follow up. At a later stage, and after radiotherapy, two lipostructure procedures improved the volumetric, soft tissue texture and functional outcomes. The combination of these techniques yielded a satisfactory morpho-functional result maintaining symmetry, function and aesthetics in the orofacial  and in the labial-commissure area.

Conclusion: A clinical case of right upper lip basocellular carcinoma is reported. Resection and immediate reconstruction with a flap rotation from the lower  lip flap according to Estlander, were carried out. During the follow-up lipostructure procedures improved volumes, functions, morphology and soft tissue texture as well.

Keywords: upper lip carcinoma, TNM, lip resection, combined rotation and advancement flaps, upper lip reconstruction, radiotherapy, lipostructure, regenerative medicine

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How to cite this article:
Luigi Clauser, Riccardo Luoni Orsi,Andrea Edoardo Bianchi. Carcinoma of the upper lip- case report and review of the literature. American Journal of Cancer Research and Reviews, 2022,6:15. DOI:10.28933/ajocrr-2022-01-2606

References:

1.Quick B.The Estlander-Abbe operation.Aust N Z J Surg.1946 Oct;16(2):142-148 doi: 10.1111/j.1445-2197.1946.tb03627.x. PMID: 20289107
2.Makoto Y., Takatoshi Y., Kyori E. Estlander flap combineted with an extended upper lip flap tecnique for large defects of lower lip with oral commissure. J Plast Reconstr Aesthet Surg.; 62(8), 997-1003, 2009. https://doi.org/10.1016/j.bjps.2008.02.013Ziate
3.Fuselier C. The partial-Thickness Cross-Lip Flap for Correction of Postoncologic Surgical Defects. J Oral Maxillofac Surg., 59, 1147-1152, 2001. https://doi.org/10.1053/joms.2001.26715
4.De Campora E., Merzetti F. “Il labbro”. La chirurgia oncologica della testa e del collo, Milano, Elsevier; 2001.
5.Neuber GA. Fetttransplantation. Dtsch. Ges. Chir. Kongr .Verh. 22:66, 1893.
6.Coleman S. R. Facial recontouring with Lipostructure. Clin.Plast. Surg. 24: 347, 1997.
7.Coleman S. R. Hand rejuvenation with structural fat grafting. Plast. Reconstr. Surg. 110: 1734-1736, 2002. https://doi.org/10.1097/01.prs.0000033936.43357.08
8.Coleman SR, ed. Structural Fat Grafting. St. Louis Missouri: Quality Medical Publishing, Inc; 2004.
9.Moseley A., Zhu M., Hedrik M. H. Adipose derived stem and progenitor cells as fillers in plastic and reconstructive surgery. Plast Reconstr. Surg. 118:121-128, 2006. https://doi.org/10.1097/01.prs.0000234609.74811.2e
10.Coleman S.R. Structural fat grafting: more than a permanent filler. Plast Reconst. Surg. 118:110, 2006. https://doi.org/10.1097/01.prs.0000234610.81672.e7
11.Cortese A., Savastano G., Felicetta L. Free fat transplantation for facial tissue augmentation. J. Oral. Maxillofac. Surg. 58:164, 2000. https://doi.org/10.1016/s0278-2391(00)90331-8
12.Coleman S.R., Saboeiro A., Sengelmann R. A comparison of lipoatrophy and aging: volume deficits in the face. Aesthetic Plast Surg. 2009;33:14-21. https://doi.org/10.1007/s00266-008-9258-z
13.Lantoni J.D., Marshall D. M., Wolfe A. S. Overgrowth of fat autotransplantedf for correction of localized steroid-induced atrophy. Plast Reconstr. Surg. 106:15661569, 2000. https://doi.org/10.1097/00006534-200012000-00018
14.Trepsat.F. Volumetric face lifting. Plast. Reconstr. Surg. 108:1358-1370, 2001. https://doi.org/10.1097/00006534-200110000-00040
15.Aust L., Devlin B., Foster, S. J., et al. Yield of human adipose derived adult stem cells from liposuction aspirates. Cytotherapy. 6: 7, 2004. https://doi.org/10.1080/14653240310004539
16.Rigotti G., Marchi A., Sbarbati A. Adipose-derived mesenchymal stem cells: past, present, and future. Aesthetic Plast Surg. 2009;33(3):271-273. https://doi.org/10.1007/s00266-009-9339-7
17.Fraser J.K., Wulur I., Alfonso Z., Hedrick M.H. Fat tissue: an underappreciated source of stem cells for biotechnology. Trends Biotechnol. 2006;24(4):150-154. https://doi.org/10.1016/j.tibtech.2006.01.010
18.Clauser L et al. Facial lipostructure in complex reconstructive surgery. Riv Ital Chir Plast. 2005, 37:75-79.
19.Clauser L. Optimizing Maxillofacial and Craniofacial Results. In: Coleman SR, Mazzola RF, eds. Fat injection From filling to regeneration. St. Louis, Missouri: Quality Medical Publishing, Inc.; 2009:475-500.
20.Clauser L. et al. Parry-Romberg Syndrome: volumetric regeneration by structural fat grafting technique. J Craniomaxillofac Surg. 2010;38:605-609. https://doi.org/10.1016/j.jcms.2010.02.005