Research Article of American Journal of Dermatological Research and Reviews
Follicular Dermatoses in Iraqi Patients (Clinical and Histopathological Evaluation)
1Professor Adil A. Noaimi MD, DDV, FICMS, 2Dr. Rusul A. Flayih MD.
1Department of Dermatology, College of Medicine, University of Baghdad. Iraqi and Arab Board for Dermatology and Venereology, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq; 2Center of Dermatology; Baghdad Teaching Hospital; Medical City,Baghdad,Iraq
Background: Follicular dermatoses are skin diseases that involved the hair follicle either early or during the course of the disease.
Objective: To collect a number of dermatoses where there is follicular involvement, to be studied and analysed in order to reach a conclusion that hair follicles are the most important target area in the pathogenesis of these dermatoses.
Patients and Methods: This is a descriptive, clinical and histopathological study that was carried out at the Centre of Dermatology and Venereology, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq during the period from December 2017 to August 2019. Forty patients with follicular dermatoses were included and all socio- demographic data related to the disease was obtained from each patient, in addition to clinical examination was performed for each patient. Lesional biopsies were done for 20 patients, for histopathological examination by Haematoxylin and Eosin (H&E).
Results: The mean age ± SD was 30.2±16.96 years, 25 patients were males and 15 patients were females, the clinical diagnosis of follicular diseases was established for all skin diseases included in the present work. The histopathological findings of lesional biopsies were mainly: perifollicular lymphocytes, follicular invasion and degeneration, follicular plugging, fibrous tract remnant, perifollicular melanophages and hair follicle cyst.
Conclusion: The result of the present study does encourage us to suggest that almost all skin diseases included in this study start initially on the hair follicle and then spread to involve the adjacent epidermis.
Keywords: Follicular dermatoses, Hair follicle.
How to cite this article:
Adil A. Noaimi, Rusul A. Flayih. Follicular Dermatoses in Iraqi Patients (Clinical and Histopathological Evaluation).American Journal of Dermatological Research and Reviews, 2020, 3:28. DOI: 10.28933/ajodrr-2020-04-0605
1. Sharquie KE, Noaimi AA, Mijthab ZM. Chronic scalp folliculitis versus acne vulgaris (observational case series study). J Clin Exp Dermatol Res. 2012; 3(153):2.
2. Thomas M, Khopkar US. Keratosis pilaris revisited: is it more than just a follicular keratosis? Int J Trichol 2012; 4:255-8.
3. Sharquie KE, Noaimi AA, Hameed AF. Lichen Planopilaris is a Common Scarring Alopecia among Iraqi Population. Journal of Cosmetics, Dermatological Sciences and Applications. 2013 Aug 16; 3(3):35-9.
4. Messenger AG, de Berker DA, & Sinclair RD. Disorders of hair in: Burns T, Breathnach S, Cox N, Griffiths C. Rook’s Text Book of Dermatology. 8th ed. UK: Wiley-Blackwell, 2010; 4, 66: 1-11.
5. Erdoğan B. Anatomy and Physiology of Hair. In Hair and Scalp Disorders 2017 May 3. (2):21.
6. Thomas LJ, Dadzie OE, Francis N, Morar N. Follicular Psoriasis-A Forgotten Entity?. Open Dermatology Journal. 2010/4:95-6.
7. Berth‐Jones J. Eczema, lichenification, prurigo and erythroderma in: Burns T, Breathnach S, Cox N, Griffiths C. Rook’s Text Book of Dermatology. 8th ed. UK: Wiley-Blackwell, 2010; Mar 22/1:1-51.
8. Cotsarelis G, Botchkarev V. Biology of hair follicles. In: Goldsmith LA, Kataz SI, Gilchrest BA, Paller SA, Leffell DJ, Wolf K (eds). Fitzpatrick’s Dermatology in General Medicine, 8thed. New York, McGrow Hill Company, 2012; 1, 15, 86: 960-8.
9. Paus R, Cotsarelis G. The biology of hair follicles. New England journal of medicine. 1999 Aug 12; 341(7):491-7.
10. Christoph T, Müller-Röver S, Audring H. The human hair follicle immun system: cellular compositon and immun privilage. . British Journal of Dermatology, 2000/142:862–73.
11. Paus R, Ito N, Takigawa M. The hair follicle and immune privilege. J Investig Dermatol Symp Proc 2003/8:188–94.
This work and its PDF file(s) are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.