ADVERSE DRUG REACTIONS AWARENESS AMONG SAMPLE OF PEOPLE IN NORTHERN REGION, SAUDI ARABIA


Adverse Drug Reactions Awareness Among Sample of People in Northern Region, Saudi Arabia


Fawwaz Freih Alshammarie [1] , Yasmeen Ali Muraizeq [2] , Rahaf Turki Aldhaban [2] , Asma Mohammed Almutairi [2] , Monerah Thaar Alshammari [2]

[1]Assistant Professor, Department of Dermatology, College of Medicine, University of Hail, Hail, Saudi Arabia.
[2]-Medical student, College of Medicine, University of Hail, Hail, Saudi Arabia.


Background: Drug reactions are a fundamental issue in many branches of medicine. Adverse drug reactions result in high mortality and morbidity globally. There is always the risk of unwanted side effects associated with the use of any substance that has a therapeutic effect. The safe use of drugs remains a critical issue for all health care professionals.

Objective: The current study investigates the level of drug reaction awareness among the public in northern Saudi Arabia.

Materials/methods: This was a questionnaire-based cross-sectional study. Data were collected using Google Forms, which were coded and processed using Microsoft Excel and SPSS version 23.

Results: Altogether 475 people participated in this study including 382 women [80.4%] and 93 men [19.6%]. Of the 475 participants, 83.6% were aware of drug reactions, 40.4% believed drug reactions are hereditary, 50.9% had received a previous skin allergy test, and 21.3% had received a previous blood test for an allergy.  

Conclusion: The public in northern Saudi Arabia are aware of drug reactions. We found that only half of the participants in our study had received a skin allergy test. It is the responsibility of physicians to provide the community with a valuable database of information on the adverse effects of drugs. We recommend that health care  institutions carry out more studies with a larger sample to improve the understanding and awareness of drug reactions.


Keywords: Adverse drug reaction, Knowledge, Awareness, North region, Saudi Arabia.

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How to cite this article:

Fawwaz Freih Alshammarie, Yasmeen Ali Muraizeq, Rahaf Turki Aldhaban, Asma Mohammed Almutairi, Monerah Thaar Alshammari. Adverse Drug Reactions Awareness Among Sample of People in Northern Region, Saudi Arabia.American Journal of Dermatological Research and Reviews, 2022, 5:55. DOI: 10.28933/ajodrr-2022-10-1505ffa


References:

1. Kaur M, Kosey S, Mehra N, Kumar R. Knowledge and awareness of adverse drug reactions. International Journal of Pharmaceutical Sciences and Research. 2015;6:4601-4610. DOI: 10.13040/IJPSR.0975-8232.6[11].4601-10.
2. Khan S A, Goyal C, Chandel N, Rafi M. Knowledge, attitudes, and practice of doctors to adverse drug reaction reporting in a teaching hospital in India: An observational study. J Nat Sci Biol Med. 2013;4[1]:191-196. DOI: 10.4103/0976-9668.107289.
3. Teo Y X, Walsh S A. Severe adverse drug reactions. Clin Med [Lond]. 2016;16[1]:79-83. DOI: 10.7861/clinmedicine.16-1-79.
4. Thomas F, Abiri OT, Komeh JP, Conteh TA, Bah AJ, Kanu JS, et al. Inconsistent Country-Wide Reporting of Adverse Drug Reactions to Antimicrobials in Sierra Leone [2017–2021]: A Wake-Up Call to Improve Reporting. International Journal of Environmental Research and Public Health. 2022 Mar 10;19[6]:3264. DOI: 10.3390/ijerph19063264
5. Coleman, J.J.; Pontefract, S.K. Adverse drug reactions. Clin. Med. 2016; 16[5]: 481–485.DOI: 10.7861/clinmedicine.16-5-481.
6. Watson S, Caster O, Rochon PA, den Ruijter H. Reported adverse drug reactions in women and men: Aggregated evidence from globally collected individual case reports during half a century. EClinicalMedicine. 2019 Oct 25;17:100188. doi: 10.1016/j.eclinm.2019.10.001. PMID: 31891132; PMCID: PMC6933269.
7. Dubrall D, Just KS, Schmid M, Stingl JC, Sachs B. Adverse drug reactions in older adults: a retrospective comparative analysis of spontaneous reports to the German Federal Institute for Drugs and Medical Devices. BMC Pharmacology and Toxicology. 2020;21[1]:1-20.OI:10.1186/s40360-020-0392-9
8. Sales I, Aljadhey H, Albogami Y, Mahmoud M A. Public awareness and perception toward Adverse Drug Reactions reporting in Riyadh, Saudi Arabia. Saudi Pharm J. 2017;25[6]:868-872. DOI: 10.1016/j.jsps.2017.01.004.
9. Jung I Y, Kim J J, Lee S J, Kim J, Seong H, Jeong W, Choi H, Jeong S J, Ku N S, Han S H, Choi J Y, Song Y G, Park J W, Kim J M. Antibiotic-Related Adverse Drug Reactions at a Tertiary Care Hospital in South Korea. Biomed Res Int. 2017;2017:4304973. DOI: 10.1155/2017/4304973.
10. Almubark R A, Aljadani R H, Alqahtani A S, Alshammari T M, BinDhim N F. National Cross-Sectional Study of Community-Based Adverse Drug Reactions in Saudi Arabia. Drugs – Real World Outcomes. 2020;7[2]:161-170. doi: 10.1007/s40801-020-00186-8.
11. Pirmohamed M, Park B K. Genetic susceptibility to adverse drug reactions. Trends Pharmacol Sci. 2001;22[6]:298-305. I: 10.1016/s0165-6147[00]01717-x.
12. Hacker M. Adverse drug reactions. Pharmacology 2009:327-352]. Academic Press. DOI: 10.1016/B978-0-12-369521-5.00013-0.
13. Wolf R, Orion E, Marcos B, Matz H. Life-threatening acute adverse cutaneous drug reactions. Clin Dermatol. 2005;23[2]:171-181. DOI: 10.1016/j.clindermatol.2004.06.012.
14. Brockow K, Przybilla B, Aberer W, Bircher AJ, Brehler R, Dickel H, Fuchs T, Jakob T, Lange L, Pfützner W, Mockenhaupt M. Guideline for the diagnosis of drug hypersensitivity reactions. Allergo Journal International. 2015 May;24[3]:94-105. DOI: 10.1007/s40629-015-0052-6.
15. Siles R I, Hsieh F H. Allergy blood testing: A practical guide for clinicians. Cleveland Clinic Journal of Medicine. 2011;78[9]:585. DOI: 10.3949/ccjm.78a.11023.
16. Rive C M, Bourke J, Phillips E J. Testing for drug hypersensitivity syndromes. Clin Biochem Rev. 2013;34[1]:15-38. PMID: 23592889
17. Huggins J L, Looney R J. Allergen immunotherapy. Am Fam Physician. 2004;70[4]:689-696. PMID: 15338781.


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