“TWO IN ONE”- A RARE CASE OF NEOPLASTIC COLLISION TUMOR

 “Two in One”- A rare case of neoplastic collision tumor

Vanessa Fonseca-Ferrer*, MD; Alba Rivera-Diaz, MD; Luis-Gerena-Montano, MD; Christian Castillo-Latorre MD; Sulimar Morales-Colon, MD;Andres Velazquez-Garcia, MD; William Rodriguez-Cintron, MD.

“Pulmonary and Critical Care Fellowship Program” VA Caribbean Health care System, San Juan, Puerto Rico.

Collision tumors are a rare group of tumoral pathologies characterized by their composition, which is based by the presence of two or more tumor types affecting the same anatomical site and separated by distinct tumor borders. These tumors may be a combination of either malignant or benign tumors [1]. Collision tumors are classified as independently coexisting neoplasms which have different genetic, behavioral, and histological features separated by a distinct demarcated border but coexist within the same organ [2]. These tumors tend to have distant immunohistochemical and morphological differences which aid in diagnosis, but can lead to confounding imaging findings, which in times, make diagnosis more challenging. According to literature this tumor tends to grow simultaneously or following each other in sequence of less than 2 months apart [3]. Accurate classification and diagnosis of these tumors is important for proper treatment options, as well as better patient outcomes. Here will be discussed a case of a rare form of collision tumor, compose of a primary lung adenocarcinoma with a mucosa-associated lymphoid tissue (MALT) lymphoma.

Keywords: Collision tumor, lung adenocarcinoma, lymphoma, combined tumor

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How to cite this article:
Vanessa Fonseca-Ferrer, Alba Rivera-Diaz, Luis-Gerena-Montano, Christian Castillo-Latorre, Sulimar Morales-Colon, Andres Velazquez-Garcia, William Rodriguez-Cintron. “Two in One”- A rare case of neoplastic collision tumor. American Journal of Histology and Cytology, 2022, 5:15. DOI: 10.28933/ajohc-2021-12-1305

References:

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