American Journal of Surgical Research and Reviews


RECONSTRUCTION OF ANTERIOR FRONTAL WALL AND CONTOURS DEFECTS USING BONE SUBSTITUTE

Research Article of American Journal of Surgical Research and Reviews Reconstruction of anterior frontal wall and contours defects using bone substitute Luigi Clauser, MD,DMD1, Antonio Lucchi, MD,DMD1, Riccardo Luoni Orsi, DMD1and Carolina Sannino MD1 1 Unit of Maxillo-Facial Surgery, Istituto Stomatologico Italiano, Via Pace, 21, 20122 MILANO, Italy Aim: The aim of this article is to report on the safety and long-term efficacy of Cerament® BoneVoid Filler bone substitute for repairing craniofacial bone defects. Post-traumatic cranioplasty is a complex and challenging procedure for all maxillo-craniofacial surgeons and neurosurgeons, especially when repairing large areas. The standard criterion  for repairing small cranial defects is the use autogenous bone from the iliac crest or split calvarial grafts. Autogenous grafts may result in donor-site morbidity, increased  surgical time, reabsorption, blood loss, and  longer recovery time . Alloplastic materials used for bone repair, such as methyl methacrylate,  hydroxyapatite, titanium, or porous polyethylene,  are expected to have optimal properties, including easy adaptation, biocompatibility,  ingrowth of new tissue, stability of shape, and low rate of reabsorption. A cranial implant  should be easily shaped and positioned, allowing  easy tissue  growth. In very wide cranium defects the new technology is a custom made cranial implant constructed three-dimensionally  with different types of materials. However, this procedure is very expensive with various infection rates depending on the  kind of material used and on the chemicophysical composition of the implant. Methods: The authors report the case of a 50-year-old man with a severe deformity of the forehead-supra orbital  area as a result of a previous complex fronto-facial trauma treated in an emergency Unit. Secondary correction and reconstruction of the residual deformities were performed by using Cerament® Bone Void Filler, an  alloplastic biphasic material, composed  of 40% hydroxyapatite, 60% calcium sulfate and the radio-contrast agent iohexol. The unique ratio of hydroxyapatite and calcium ...

TRANSLATIONAL MEDICINE AND AUTOLOGOUS FAT TRANSFER: FROM BENCH TO BEDSIDE. REGENERATIVE AND PROLIFERATIVE POTENTIAL OF ADIPOSE TISSUE

Research Article of American Journal of Surgical Research and Reviews Translational Medicine and Autologous Fat Transfer: From bench to bedside. Regenerative and proliferative potential of adipose tissue Andrea Edoardo Bianchi, MD1,2, Antonio Lucchi, MD1, Riccardo Luoni Orsi, DMD1, Luigi Clauser, MD1 1Unit of Maxillo-Facial Surgery, Istituto Stomatologico Italiano, Via Pace, 21, 20122 MILANO, Italy; 2University UniCamillus, Via di Sant’Alessandro, 8, 00131 ROME, Italy Aim: Autologous fat transfer (AFT) for the correction of maxillofacial defects was first reported at the end of the 19th century. AFT was introduced as a way of improving facial esthetics and in the last few years has expanded into applications in craniomaxillofacial reconstructive surgery and regenerative therapy. This protocol is part of translational medicine. The aim of translational medicine, or translational science, is to combine disciplines, resources, expertise, and techniques based on three main pillars: bench, bedside, and community. The primary goals to coalesce assets of various natures to significantly improve the global healthcare system. AFT is thus part of translational medicine in tissue healing, regeneration and augmentation. Methods: Several techniques have been suggested for harvesting and grafting the fat. The Authors follow Coleman’s technique with centrifugation and infiltration using different types and sizes of cannulas. Conclusion: This review provides a fairly comprehensive summary of the many exciting possibilities that exist in the field of facial fat grafting. Five clinical cases are presented and discussed. Translational medicine is the basis of this new reconstructive and regenerative field of science and research. Keywords: Regenerative medicine, translational medicine, lipofilling, fat grafting, adipose-derived-stem-cells, fat graft survival, fat graft processing, maxillofacial surgery, soft tissue reconstruction, stem cells, bench to bedside ...

SINGLE STITCH OPEN INTERVAL APPENDECTOMY; WHEN AND WHY

Case Report of American Journal of Surgical Research and Reviews Single stitch Open interval appendectomy; when and why Dr.jitendra kumar Saroj1, Dr santosh Gautam2 1Assistant professor, Department of general surgery Venkateshwara institute of medical sciences, Gajraula, INDIA; 2Assistant professor, Department of general surgery, Prasad institute of medical sciences,Sarojani Nagar Lucknow, Santosh Gautam Appendicitis is a very common cause of acute abdomen. Most of the patient admit in surgical emergency. Diagnosis usually made clinically, sonography sometimes may be helpful. Regarding management there is still controversy exists. Developed country usually performed laparoscopy appendectomy while in developing country surgical management is still in debate. Different surgeons have different opinion either emergency open or laparoscopy appendectomy or interval appendectomy. Even in open appendectomy there is still debate between classical procedure vs small incision. This study favors single stitch surgery rather than classical and laparoscopy appendectomy. this case study supports even better cosmetic and outcome than laparoscopy appendectomy. Keywords: single stitch, interval appendectomy, classical, laparoscopic ...

BLUE ROUND SMALL CELL TUMOR: A SURGICAL UPDATE OF DSRCT WITH REVIEW OF LITERATURE ‘A GRIM AFFAIR’

Research Article of American Journal of Surgical Research and Reviews Blue Round Small Cell tumor: A Surgical Update of DSRCT with review of literature ‘A Grim Affair’ Dr.UwaisRiazUlHasan3 M.Med, Dr.Khathija Hasan M.Med, Dr.Farooq Ahmed Qureshi MS, Dr. Victor Effiong Obong M.B.B.Ch, MWACS, Dr.Abdul Aziz Al Nami M.B.B.S, Dr.Ali Ibrahim AlShaqaqiq M.B.B.S, Dr.Mohammad AbdulMajeed Alghadeer M.B.B.S Dr. Marwan Ahmad AlRayhan M.B.B.S, Dr. Mohammed Ali AlJummah M.B.B.S, Dr.Baqer Ali Aldheen M.B.B.S, Dr. Ali Hussain AlRufayi MD, Dr.ShehlaRiazUlHasan Phd. Dr. Moath AbdulAziz AlMasoud2 M.D, Dr. Noura Al Dossary1 Department of General Surgery, Al Omran General Hospital, Al Hassa, Kingdom of Saudi Arabia. Hospital Director1,Head of department2, Assoc Consultant General Surgeon3 Desmoplastic small round cell tumor (DSRCT) is a tumor derived from the Greek desmos referring to knot and plasis to formation an uncommon soft tissue malignant tumor, mesenchymal in origin and aggressive with a prelidiction for males and advanced at presentation. It was first described as a distinct clinical entity by Gerald WL and Rosai J (7). There are fewer than 200 reported to date. Depending on the primary site of location the Clinical manifestations vary. As most arise from the abdomen and pelvis they remain asymptomatic till they attain a huge size. Other reported sites are the skull, thorax, and paratesticular region (10,13). We report the case of a 19 yr old male who had non specific abdominal discomfort with asthenia for a period of six months and was referred to us for evaluation of left supraclavicular nodes. The prognosis of Desmoplastic small round cell tumor (DSRCT) is poor with few surviving less than two years. Keywords: Blue round, Desmoplastic small round cell tumor, Radiology, Multimodal therapy ...

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American Journal of Surgical Research and Reviews

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