IJCR (2018), Volume 2

Primary cerebral lymphoma is a form of non-Hodgkin lymphoma with a solitary localization in the brain, excepting other localizations involving the central nervous system. This is a rare cancer but with increasing incidence, it was predominantly observed in immunodepressed HIV-positive patients but since the advent of effective antiretroviral treatments, it has essentially been observed in immunocompetent patients. We report two cases of primary cerebral lymphoma observed in immunocompetent patients.

Human echinococcosis is a zoonotic infection caused by larval forms (metacestodes) of tapeworms of the genus echinococcus found in the small intestine of carnivores. The eggs of these tapeworms excreted by carnivores may infect various species of natural intermediate host animals and humans. Hydatid cysts may be found in almost any part of the body, leading to many clinical presentations. The most common locations are the liver and lungs (2). In the heart, the left ventricle is the most common location (46%), followed by the right ventricle (21%), interventricular septum (19.3%), right atrium (9.7%), left atrium (1.6%), and sinus of valsalva (1.6%) .The treatment of intracardiac hidatid cyst is surgery (3).

Angiomatous meningioma (AM) is a rare subtype of meningioma characterized by highly vascular tumor tissue comprising predominantly variable sized hyalinized blood vessels. This manuscript describes a case of intracranial Angiomatous meningioma and reports briefly its clinical, radiological, histopathological and therapeutic characteristics through a literature review.

Colchicine is an anti-inflammatory alkaloid used for the treatment and prevention of gout, and more recently for the treatment of familial Mediterranean fever (FMF). It has a narrow therapeutic index, with no clear- cut distinction between nontoxic , toxic and lethal doses. Colchicine is rapidly absorbed from the gastrointestinal tract after ingestion, In patients with pre exciting renal and hepatic impairment the possibility of toxicity greatly increases.The clinical course of acute colchicine overdose is divided into three sequential and usually overlapping phases. The first phase is gastrointestinal and the second phase is multi organ failure and death will occur in this phase, the third phase is the recovery stage typically occurs after weeks. We present 38 years old patient who presented to our hospital Accident and Emergency after 8 hours of ingestion of 40 tablets of colchicine. Patient was complaining of nausea and vomiting with repeated watery diarrhea. After 24 hours, Patient was diaphoretic , orthopenic and tachycardic , fluid resuscitation was ongoing , but as patient hemodynamic was unstable requiring vasopressor support patient was shifted to ICU.As the patient had worsening lactic acidosis and acute kidney injury, elective intubation was done and patient was mechanically ventilated. During this stage patient was in multi organ failure (cardiogenic shock, coagulopathy, acute kidney injury, pancytopenia and electrolyte disturbance). After 10 days Patient was tracheostomized due to prolonged intubation , then gradually weaned from mechanically ventilation , pancytopenia resolved with rebound leukocytosis but with delayed in recovery of kidneys so CRRT was continued till renal recovery that was achieved after 3 weeks , Successfully the patient had his tracheostomy tube de-cannulated and discharged after full recovery.

Intrauterine device (IUD) is the commonest method of contraception used by women. Complete migration into the urinary bladder though rare, results in lower urinary tract symptoms and stone formation around the migrated IUD. We present a 53 year old woman with a missing IUD (Copper T) who presented with lower urinary tract symptoms and haematuria. Cystoscopy showed a bladder stone anchored to the anterior bladder wall by an intrauterine device. She had cystolithotomy and retrieval of oblong shaped stone measuring about 3cm and intact IUD (Copper T) after failed endoscopic procedure. Adequate counselling prior to insertion is important. This will reduce the incidence of missing IUD.