Music is a universal language. It influences all levels of human existence. It is a medium for communication, which can be both a pleasant and healing experience. Modern science and medicine are now rediscovering the healing powers of music. And various ragas in Hindustani & Karnataka treating persons with special needs in mental and physical health, rehabilitation and special education is gaining ground. It is a great ancient holistic medical science of India. The whole subject of music medical therapy is now getting attention from all across the world. In this paper we are presenting how a different raga affects the human body.