Histopathological Changes Of Cerebral Vessels Secondary To Drug Abuse
Drug abuse has been associated with a number of cerebrovascular adverse effects, such as hemorrhagic and ischemic stroke. Heroin, cocaine and amphetamines are the most commonly abused substances but a systematic pathology study of their effects on human cerebral vessels has not been conducted to date. We present a post-mortem, comparative, pathology study on the brains of drug addicts and healthy controls. The aim of this study was to determine the pathological changes of the vascular lumen, vascular wall and perivascular areas observed in the post-mortem brain of drug addicts compared to those of non-drug addicts healthy controls.
Management of Post Bilateral Pontine Haemorrhage with Ayurveda
Background and Purpose. This case report documents the management of residual paralysis due to a rare and fatal disease – hemorrhagic leukoencephalitis with Ayurveda. The purpose of this report is to illustrate the role of Ayurvedic treatment methodology for management of such neurological disorders. Case Description: Mrs. PM was a 31 year old lady who suffered from an attack of acute hemorrhagic leukoencephalitis after her second delivery. She had left hemiplegia with right sided LMN facial palsy with nystagmus and loss of control of posture and whole-limb movements. Some residual ability to use the right hand and fingers remained, provided the trunk and right upper arm were stabilized. Her cognitive power remains undiminished. Computed tomographic scans verified acute bilateral paramedian pontine hemorrhage with intraventricular extension. It also showed chronic infarcts in bilateral external capsules. Discussion. 15 days treatment with Ayurvedic medicines and Panchakarma procedures including Nasya and Tarapan therapies showed significant improvement in nystagmus, postural abnormalities and whole – body movement.
